COPD Flashcards
(49 cards)
What are some obstructive airway diseases ?
- asthma
- cystic fibrosis
- COPD
What is COPD ?
progressive lung disease characterized by persistent airflow limitation
- associated with chronic inflammatory response in lungs and airway
What can cause COPD ?
- primarily caused by cigarette smoking and other particles and gas
- may have genetic deficiency of alpha-1 antitrypsin (A1AD)
What is chronic bronchitis ?
the presence of cough and sputum production for at least 3 months in each of two consecutive years
What is emphysema ?
loss of lung elasticity and hyperinflation of lung tissue
- causes the destruction of alveoli
What other conditions are included within a COPD diagnosis ?
chronic bronchitis & emphysema
What is the pathophysiology of COPD ?
chronic inflammation of airways, lung parenchyma and pulmonary blood vessels which leads to increased mucus production and a structural change in the lungs leading to airway constriction
What is the defining feature of COPD
airflow limitation during forced exhalation
- inability to expire air
- the air becomes trapped so the pt’s is having to inhale when the lungs are already in a “over-inflated” state
What is bullae and blebs ?
- Bullae: large air spaces
- Blebs: air spaces next to pleurae
What does having COPD lead to ?
- airflow limitations
- air trapping
- poor gas exchange
- wall of alveoli destroyed
- formation or bullae and blebs
- will eventually lead to hypoxia and retained CO2
What are some clinical manifestations of COPD ?
- chronic intermittent cough
- wheezing on auscultation, in late stages may be more diminished
- barrel chested and purse lipped
- clubbing and polycythemia vera
- fatigue and decrease activity tolerance
- use of accessory muscles to breathe
- prolonged expiratory phase
- thin in appearance
- cor pulmonale
- hypercapnia
What are some diagnostic studies ?
- history and physical: smoking history and functional ability
- chest x-ray
- O2 sats: with COPD normal is usually 88-92%
- 6-minute walk index
- COPD assessment test (CAT)
- pulmonary function test
- ABGs
What does a pulmonary function test measure ?
tests FEV1 (forced expiratory volumes) calculates the amount of air that a person can force out of their lungs in 1 sec
What is the primary cause of COPD exacerbations ?
bacterial and viral infections
What are some S&S of a COPD exacerbation ?
- increased wheezing
- acute change in usual patterns of dyspnea, cough, or sputum
- malaise, fatigue, confusion, depression, anxiety
- severe: accessory muscle use, central cyanosis, altered LOC, edema in lower extremities/signs of rt sided HF, unstable BP
What can happen if someone has a severe COPD exacerbation ?
- acute respiratory failure
- need to be intubated
What is the first complications of COPD ?
pulmonary hypertension
What causes pulmonary hypertension ?
- alveolar hypoxia causes constriction of pulmonary vessels
- chronic hypoxia stimulates RBC production which causes polycythemia which increases the viscosity of blood
- this leads to increased pulmonary vascular resistance which causes the pulmonary hypertension
What causes Cor Pulmonae ?
pulmonary hypertension pressure increases within the lungs
- the pressures on the Rt side of the heart must increase to push blood into the lungs
- leads to S&S of Rt sided HF
- late manifestation, worse prognosis, may need to be on palliative care
How do bronchodilators help with COPD ?
opens up the airways
How do anticholinergic bronchodilators help with COPD ?
relax muscles around bronchi to bronchodilate
How do steroids help with COPD ?
reduce inflammation
- prednisone/prednisolone
How do antibiotics help with COPD ?
will treat the bacterial infection if there is one
- test sputum to find the bacteria
What is a bullectomy ?
removal of large air spaces to improve lung function
- thru a thorascope