COPD

Question 1

COPS most common symp

Answer 1

Main-
Dyspnea
Cough
Sputum

and also-
Wheezing
Chest tightness
Fatigue
Weight loss
Syncope

Question 2

What is required to make COPD diagnosis

Answer 2

Spirometry

Question 3

Spirometry values to determine COPD

Answer 3

FEV1/FVC < 0.7

Confirms persistant airflow limitation

Question 4

Key indicators for considering COPD diagnosis

Answer 4

Dyspnea that progresses in time
Chronic cough
Chronic sputum
Recurrent LRTI
Risk factors (smoking...)
Family history of COPD

Question 5

DD of COPD

Answer 5

Asthma
Lung cancer
TB
Bronchiectasis
LHF
CF

Question 6

Which one goes down in COPD patients?

FEV1
FVC

Answer 6

Both, But FEV1 goes even lower

Question 7

GOLD1

Answer 7

Mild

FEV1 > 80% Predicted

Question 8

GOLD2

Answer 8

Moderate

FEV1 50-80% Predicted

Question 9

GOLD3

Answer 9

Severe

FEV1 30-50% Predicted

Question 10

GOLD4

Answer 10

Very severe

FEV1 < 30% Predicted

Question 11

COPD exacerbation classified as

Answer 11

Mild
Moderate
Severe

Question 12

How do we treat Mild COPD exacerbation?

Answer 12

Slow Acting Broncho-Dilators

Question 13

How do we treat Moderate COPD exacerbation?

Answer 13

SABD
Oral AB
Oral corticosteroids

Question 14

How do we treat Severe COPD exacerbation?

Answer 14

Hospetalization

Question 15

Prevention and Maintenance therapy

Answer 15

Smoking cessation
Influenza vaccination
Pneumococcal vaccine
Rehabilitatio
Oxygen therapy

Question 16

Which adrenergic R are prsent in the lungs

Answer 16

B-2

Question 17

Example for short acting B2-agonists

Answer 17

Salbutamol (Albuterol)

Fenoterol

Question 18

Example for long acting B2-agonists

Answer 18

Formoterol

Salmeterol

Question 19

Muscarinic antagonists long acting examples

Answer 19

Tiotropium

Aclidinium bromide

Question 20

Muscarinic antagonists short acting examples

Answer 20

Ipratropium

Oxitropium

Question 21

Goals for treatment of stabe COPD

Answer 21

Reduce symp.

Reduce risk

Question 22

Describe the management cycle

Answer 22

Review
Assess
Adjust

Question 23

Stable COPD treatment choice-

We choose group A or B options when the patient-

Answer 23

Had 0-1 moderate exacerbations

Question 24

Stable COPD treatment choice-

We choose group C or D options when the patient-

Answer 24

Had > 2 moderate exacerbation

or

1 leading to hospitalization

Question 25

Group A is treated with

Answer 25

Bronchodilator

Question 26

Group B is treated with

Answer 26

LABA or LAMA

Question 27

Group C is treated with

Answer 27

LAMA

Question 28

Group D is treated with

Answer 28

``` LAMA or LAMA+LABA or ICS+LABA ```

Question 29

Most common cause for COPD exacerbation

Answer 29

Respiratory tract infections

Question 30

COPD patients with acute respiratory failure should be given

Answer 30

Non-Invasive mechanical ventilation

Question 31

2 Symptoms assessment tests:

Answer 31

CAT (COPD Asse. Test) | mMRC (modified Medical Research Council)

Question 32

CAT test- What does it contain?

Answer 32

8 questions Answers 0-5 Score 0-40

Question 33

mMRC test- What does it contain?

Answer 33

Tick 1 box only that applies to you | Grade 0-4

Question 34

What blood count can predict exacerbation rate?

Answer 34

Eosinophils count in patients treated with LABA without ICS

Question 35

Group A and C when assesment test is

Answer 35

mMRC 0-1 | CAT < 10

Question 36

Group B and D when assesment test is

Answer 36

mMRC > 2 | CAT > 10

Question 37

Define what is COPD exacerbation-

Answer 37

Acute worsening of respiratory symptoms that results in additional therapy

Question 38

How do you usually treat acute exacerbation?

Answer 38

SABA with or without SAMA