COPD Flashcards

1
Q

Symptoms of COPD

A

Shortness of breath

Chronic cough

Sputum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

COPD risk factors

A

Tobacco

Occupation

Indoors and outdoor pollution

Host-factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is required to establish diagnosis of COPD

A

Spirometry

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Dyspiea with COPD

A

Progressive over time

Worse during exercise

Persistent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Chronic cough with COPD

A

Maybe intermittent and unproductive

Presents with recurrent wheezing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Chronic sputum production and COPD

A

Any form may indicate COPD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Recurrent lower respiratory tract infection

A

Indicates COPD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

History of Risk factors

A

Genetic factors

Congenital or developmental abnormalities

Tobacco

Smoke from other source

Occupational dust, fumes, gases, vapors and other chemical

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Family history or childhood factors

A

Low birth weight

Childhood respiratory infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Mild severity of COPD

A

FEV1 ≥ 80% predicted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Moderate severity

A

50% ≤ FEV1 ≤ 80% predicted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Severe severity

A

30% ≤ FEV1 ≤ 50% predicted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Very severe severity

A

FEV1 < 30% predicted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

mMRC grade 0

A

Out of breath with strenuous exercise

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

mMRC grade 1

A

Speed walking on a leveled ground or walking up a slight hill

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

mMRC grade 2

A

Walker slower than age group because of breathlessness

Or

Stop to catch a breath when walking at pace on a leveled ground

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

mMRC grade 3

A

Catch breath after 100 meters or few minutes while walking on a leveled ground

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

mMRC grade 4

A

Too breathless to leave the house or depressing or undressing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

0 or 1 hospitalization

mMRC 0-1

CAT < 10

A

Group A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

0 or 1 hospitalization

mMRC ≥ 2

CAT ≥ 10

A

Group B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

≥ 2 or ≥ 1 hospitalization

mMRC 0-1

CAT < 10

A

Group C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

≥ 2 or ≥ 1 hospitalization

mMRC ≥ 2

CAT ≥ 10

A

Group D

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What are the non pharmacological therapy for COPD

A

Smoking cessation

Vaccination

Pulmonary rehabilitation

Physical activity

Appropriate inhaler technique and adherence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Group A initial treatment

A

Bronchodilator

25
Group B initial treatment
LAMA or LABA
26
Group C initial treatment
LAMA
27
Group D initial treatment
LAMA or LAMA + LABA or ICS + LABA
28
What immediate relief therapy should all COPD Patient be offered
short acting bronchodilator SAMA + SABA
29
Group A explained
Few symptom and low exacerbation risk Short or long acting bronchodilator offered and continued if benefit is observed
30
Group B explained
More symptoms and low risk of exacerbation LAMA or LABA
31
Group C explained
Few symptoms and high risk of exacerbation LAMA preferred
32
Group D explained
Frequent symptoms and high risk of exacerbation LAMA If CAT > 20 LAMA + LABA If eosinophils > 300 or history of asthma LABA + ICS
33
SABA: Albuterol dosing
90 mcg 2 inhalation q 4-6 hours prn Onset: 4-6 hours
34
SABA: Levalbuterol
45-90 mcg 2 inhalation q 4 hours prn Onset: 6-8 hours
35
12 hours or twice daily dosing LABA
Formoterol Arformoterol Salmeterol
36
24 hours or once daily dosing LABA
Indacaterol Olodaterol
37
SAMA
Ipatropium bromide 2 inhalation q 6 hours Duration: 6-8 hours
38
12 hours LAMA or twice daily dosing
Aclinidium Bromide 2 inhalation BID Glycopyrronium bromide 1 capsule inhaled BID
39
24 hours or once daily dosing LAMA
Tiotropium Umeclidinium
40
Antimuscarinic ADR
ANTI-SLUD
41
True/False: LAMA and SAMA can be administered together
False
42
Use of ICS-LABA has strong support for which group
Group D History of hospitalization and exacerbation ≥2 COPD moderate exacerbation per year Eosinophils > 300 cells/ul History of asthma
43
ICS-LABA should be considered for use in which patient group
1 moderate exacerbation per year Blood eosinophils 100-300 cells/ul
44
What patient group should not use ICS-LABA
Repeated pneumonia event Eosinophils < 100 cells/ul History of mycobacterial infection (TB)
45
12 hours or twice daily dosing LABA + ICS
Symbicort Dulera Advair
46
24 hours or once daily dosing LABA + ICS
Breo Ellipta
47
24 hours or once daily dosing LABA + LAMA + ICS
Trelegy Ellipta
48
Draw the follow up chart for COPD pharmacological treatment for exacerbation and dyspnea
On notability
49
When do you discontinue inhaled corticosteroids in patients with COPD
Active or risk of pneumonia
50
What is exacerbation
Acute worsening of respiratory symptoms that require an addition therapy
51
How is mild exacerbation managed
Short acting bronchodilator
52
How is moderate exacerbation managed
Short acting bronchodilator + antibiotic with or without oral corticosteroids
53
How is severe exacerbation managed
Hospitalization
54
What can trigger COPD exacerbation
Viral infection Bacterial infection Environmental factors Ambient temperature
55
Cord exacerbation characteristics
Increased sputum production ( Purulence and volume) Increased cough
56
Now Lang does exacerbation symptoms last
7-10 days
57
How can COPD exacerbation be managed pharmacologically
Bronchodilators • Increase doses/frequencies of SABD • Combine SABA and SAMA • Consider using LABD when patient is stable • Use spacers/nebulizers when appropriate • Use oral corticosteroids (5-7 days) • Consider oral antibiotics when signs of bacterial infection present (5-7 days) • Increased sputum production, increased sputum purulence, increased dyspnea • Consider non-invasive mechanical ventilation (CPAP/BiPAP/etc.)
58
What is Roflumilast
PDE-4 inhibitor Dose once daily by mouth 500 mcg
59
When is azithromycin used
Prevent COPD exacerbation 250mg daily or 250-500 mg 3x weekly