COPD and Asthma Flashcards

1
Q

Risk factors for asthma

A
Allergens 
Respiratory infections 
Occupational irritants 
Smoking
Air pollution
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2
Q

Risk factors for COPD

A

Smoking

Occupational dust and chemicals

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3
Q

DRAW the asthma ladder

A

Slide 11

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4
Q

COPD group A conditions

A

0-1 moderate exacerbations (not leading to hospital admission
mMRC 0-1, CAT<10

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5
Q

COPD group A treatment

A

SABA OR SAMA OR LABA OR LAMA

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6
Q

COPD group B conditions

A

0-1 moderate exacerbations (not leading to hospital admission)
mMRC greater than 2, CAT more than 10

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7
Q

COPD group B treatment

A

Lama or laba

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8
Q

COPD group C conditions

A

More than 2 moderate exacerbations or more than 1 leading to hospitalisation
mMRC more than 2, CAT more than 10

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9
Q

COPD group c treatment

A

LAMA

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10
Q

COPD group d conditions

A

More than 2 moderate exacerbations or 1 or more leading to hospitalisation
mMRC more than 2, CAT more than 10

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11
Q

COPD group d treatment

A

LAMA
Lama+laba
ICS+laba

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12
Q

Asthma COPD non Pharm

A
Avoid tobacco 
More physical activity
Avoid medications that make it worse (NSAIDs, BB) 
Allergen avoidance 
Vaccination (flu and pneumonia)
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13
Q

SABA SE

A

Trembling hands
Tachycardia
Headache (usually with oral)

SABA only treatment increase the risk of severe exacerbations compared to ICS add on

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14
Q

Salbutamol dosing

A

100mcg inhaler

1-2 puffs tds-qds prn

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15
Q

Salbutamol tablets and syrup 2-6 yo dosing

A

0.1-0.2mg/kg/dose tds

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16
Q

Salbutamol tablet and syrup 6-14 yo dosing

A

2mg tds-qds (max 24mg/day)

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17
Q

Salbutamol oral >14yo dosing

A

2-4mg tds-qds prn (max 32mg/day)

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18
Q

LABA SE

A

Tremor
Tachycardia
Headache

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19
Q

Which LABA can be used for exacerbations

A

Symbicort (formeterol)

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20
Q

ICS examples

A

Budesobide
Beckoned has one
Fluticasone

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21
Q

ICS SE

A

Mouth and throat irritation
Oral thrush
Hoarseness of voice

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22
Q

Counselling points for ICS

A

Rinse mouth after use

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23
Q

Beclomethadone dipropionate total daily ICS dose

A

Low: 200-500
Medium >500-1000
High: >1000

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24
Q

budesonide dosing

A

Low: 200-400
Medium: >200-400
Hugh: >400

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25
Fluticasone furoate dosing
Low-medium 100 | High 200
26
Fluticasone propionate dosing
Low 100-250 Medium 250-500 High 500
27
Mometasone furoate dosing
Low medium 200-400 | High 400
28
Beclomethasone dipropionate children 6-11 yo dosing
Low 100-200 Medium 200-400 High 400
29
Budesonide children 6-11 yo dosing
Low 100-200 Medium 200-400 High 400
30
Fluticasone furoate children 6-11 yo dosing
Low medium 50
31
Fluticasone propionate children 6-11 yo dosing
Low 50-100 Medium 100-200 High 200
32
Mometasone furoate children 6-11 yo dosing
Low medium 100 | High 200
33
Seretide 25/50 composition
Fluticasone 50 | Salmeterol 25
34
Seretide evohaler general dosing
1-2 puffs OD-BD
35
Seretide evohaler min age
25/50 4yo | 25/125, 25/250 12yo
36
Seretide accuhaler general dosing
1 puff OD-BD
37
Seretide accuhaler min she
50/100 4yo | 50/250 and 50/500 12yo
38
Symbicort usual dose
1-2 puff BD | Max dose: 4 puff BD
39
Symbicort rapihaler dosing
2-4 puffs BD | Max 8 puff BD
40
Ipratropium SE
Dry mouth, metallic taste | Relieved by sipping water or sucking on candy
41
Systemic effects of ipratropium
Blurred vision uncommon | Urinary retention
42
Ipratropium dosing
20mcg | 2 puffs tds-qds prn
43
Berodual composition
Ipratropium 20mcg | Fenoterol 50 mcg
44
Berodual N dosing
1-2 puffs | Max 8 a day
45
Spirits dosing
2 inhalations (5mcg) OD
46
Incruse dosing
1 inhalation OD
47
Anoro Ellipta dosing
Umexlidinium 62.5mcg | Vilanterol 25mcg
48
Anoro dosing
1 inhalation OD
49
LTRA
Montelukast
50
Montelukast MOA
Prevent airway smooth muscle contraction and inflammation caused by laukotrienes
51
Montelukast SE
HA abdominal pain diarrhoea Depression agitation Attention and memory data am ex Hallucinations suicidal behaviour
52
Theophylline MOA
Relax airway muscles
53
Theophylline SE
``` Difficulty sleeping Agitation palpitations Muscle tremors Restlessness N/v ```
54
Theophylline antibiotic interactions
Clarithromucin Erythromycin Cipro Ketoconazole
55
Theophylline antidepressant interaction
Fluvoxamine
56
Theophylline antiepileptic interaction
Phenytoin | Carbamazepine
57
Theophylline CCB interaction
Diltiazem | Verapamil
58
Theophylline h2 receptor antagonist interaction
Cimetidine
59
Theophylline other interactions
Caffeine
60
Prednisone adult dosing
Adults 1mg/kg/day Usual 30 mg Max 50mg 5-7 days
61
prednisolone children dosing
1-2mg/kg/day max 40mg (6-11 yo), 30mg (2-5yo) 3-5 days
62
prednisolone short term use SE
sleep disturbances, mood changes, gastric irritation, hyperglycaemia
63
prenisolone systemic SE
osteoporosis, cataracts, glaucoma, weight gain, worsening of sugar control in diabetic patients
64
mucolytics usage in COPD
make mucus less viscous/ reduce exacerbation