COPD and Asthma Flashcards

1
Q

Risk factors for asthma

A
Allergens 
Respiratory infections 
Occupational irritants 
Smoking
Air pollution
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2
Q

Risk factors for COPD

A

Smoking

Occupational dust and chemicals

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3
Q

DRAW the asthma ladder

A

Slide 11

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4
Q

COPD group A conditions

A

0-1 moderate exacerbations (not leading to hospital admission
mMRC 0-1, CAT<10

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5
Q

COPD group A treatment

A

SABA OR SAMA OR LABA OR LAMA

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6
Q

COPD group B conditions

A

0-1 moderate exacerbations (not leading to hospital admission)
mMRC greater than 2, CAT more than 10

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7
Q

COPD group B treatment

A

Lama or laba

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8
Q

COPD group C conditions

A

More than 2 moderate exacerbations or more than 1 leading to hospitalisation
mMRC more than 2, CAT more than 10

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9
Q

COPD group c treatment

A

LAMA

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10
Q

COPD group d conditions

A

More than 2 moderate exacerbations or 1 or more leading to hospitalisation
mMRC more than 2, CAT more than 10

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11
Q

COPD group d treatment

A

LAMA
Lama+laba
ICS+laba

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12
Q

Asthma COPD non Pharm

A
Avoid tobacco 
More physical activity
Avoid medications that make it worse (NSAIDs, BB) 
Allergen avoidance 
Vaccination (flu and pneumonia)
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13
Q

SABA SE

A

Trembling hands
Tachycardia
Headache (usually with oral)

SABA only treatment increase the risk of severe exacerbations compared to ICS add on

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14
Q

Salbutamol dosing

A

100mcg inhaler

1-2 puffs tds-qds prn

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15
Q

Salbutamol tablets and syrup 2-6 yo dosing

A

0.1-0.2mg/kg/dose tds

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16
Q

Salbutamol tablet and syrup 6-14 yo dosing

A

2mg tds-qds (max 24mg/day)

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17
Q

Salbutamol oral >14yo dosing

A

2-4mg tds-qds prn (max 32mg/day)

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18
Q

LABA SE

A

Tremor
Tachycardia
Headache

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19
Q

Which LABA can be used for exacerbations

A

Symbicort (formeterol)

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20
Q

ICS examples

A

Budesobide
Beckoned has one
Fluticasone

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21
Q

ICS SE

A

Mouth and throat irritation
Oral thrush
Hoarseness of voice

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22
Q

Counselling points for ICS

A

Rinse mouth after use

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23
Q

Beclomethadone dipropionate total daily ICS dose

A

Low: 200-500
Medium >500-1000
High: >1000

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24
Q

budesonide dosing

A

Low: 200-400
Medium: >200-400
Hugh: >400

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25
Q

Fluticasone furoate dosing

A

Low-medium 100

High 200

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26
Q

Fluticasone propionate dosing

A

Low 100-250
Medium 250-500
High 500

27
Q

Mometasone furoate dosing

A

Low medium 200-400

High 400

28
Q

Beclomethasone dipropionate children 6-11 yo dosing

A

Low 100-200
Medium 200-400
High 400

29
Q

Budesonide children 6-11 yo dosing

A

Low 100-200
Medium 200-400
High 400

30
Q

Fluticasone furoate children 6-11 yo dosing

A

Low medium 50

31
Q

Fluticasone propionate children 6-11 yo dosing

A

Low 50-100
Medium 100-200
High 200

32
Q

Mometasone furoate children 6-11 yo dosing

A

Low medium 100

High 200

33
Q

Seretide 25/50 composition

A

Fluticasone 50

Salmeterol 25

34
Q

Seretide evohaler general dosing

A

1-2 puffs OD-BD

35
Q

Seretide evohaler min age

A

25/50 4yo

25/125, 25/250 12yo

36
Q

Seretide accuhaler general dosing

A

1 puff OD-BD

37
Q

Seretide accuhaler min she

A

50/100 4yo

50/250 and 50/500 12yo

38
Q

Symbicort usual dose

A

1-2 puff BD

Max dose: 4 puff BD

39
Q

Symbicort rapihaler dosing

A

2-4 puffs BD

Max 8 puff BD

40
Q

Ipratropium SE

A

Dry mouth, metallic taste

Relieved by sipping water or sucking on candy

41
Q

Systemic effects of ipratropium

A

Blurred vision uncommon

Urinary retention

42
Q

Ipratropium dosing

A

20mcg

2 puffs tds-qds prn

43
Q

Berodual composition

A

Ipratropium 20mcg

Fenoterol 50 mcg

44
Q

Berodual N dosing

A

1-2 puffs

Max 8 a day

45
Q

Spirits dosing

A

2 inhalations (5mcg) OD

46
Q

Incruse dosing

A

1 inhalation OD

47
Q

Anoro Ellipta dosing

A

Umexlidinium 62.5mcg

Vilanterol 25mcg

48
Q

Anoro dosing

A

1 inhalation OD

49
Q

LTRA

A

Montelukast

50
Q

Montelukast MOA

A

Prevent airway smooth muscle contraction and inflammation caused by laukotrienes

51
Q

Montelukast SE

A

HA abdominal pain diarrhoea
Depression agitation
Attention and memory data am ex
Hallucinations suicidal behaviour

52
Q

Theophylline MOA

A

Relax airway muscles

53
Q

Theophylline SE

A
Difficulty sleeping 
Agitation palpitations 
Muscle tremors 
Restlessness 
N/v
54
Q

Theophylline antibiotic interactions

A

Clarithromucin
Erythromycin
Cipro
Ketoconazole

55
Q

Theophylline antidepressant interaction

A

Fluvoxamine

56
Q

Theophylline antiepileptic interaction

A

Phenytoin

Carbamazepine

57
Q

Theophylline CCB interaction

A

Diltiazem

Verapamil

58
Q

Theophylline h2 receptor antagonist interaction

A

Cimetidine

59
Q

Theophylline other interactions

A

Caffeine

60
Q

Prednisone adult dosing

A

Adults 1mg/kg/day
Usual 30 mg
Max 50mg
5-7 days

61
Q

prednisolone children dosing

A

1-2mg/kg/day
max 40mg (6-11 yo), 30mg (2-5yo)
3-5 days

62
Q

prednisolone short term use SE

A

sleep disturbances, mood changes, gastric irritation, hyperglycaemia

63
Q

prenisolone systemic SE

A

osteoporosis, cataracts, glaucoma, weight gain, worsening of sugar control in diabetic patients

64
Q

mucolytics usage in COPD

A

make mucus less viscous/ reduce exacerbation