Corticosteroids

Question 1

Alimentary canal mucosal protection

Answer 1

PGE2

Question 2

Maintenance of renal blood flow and sodium excretion in low volume or low output state

Answer 2

PGE2

Question 3

Regulation of platelet function

Answer 3

PGI2 and TXA2

Question 4

Oxytocin and pregnant uterus

Answer 4

PGE2 and PGF2a

Question 5

Vasodilation

Answer 5

PGE2, D2

Question 6

Vascular permeability

Answer 6

PGE2, LTs

Question 7

Hyperalgesia

Answer 7

All PGs

Question 8

Chemotaxis

Answer 8

5-HETE and LTB4

Question 9

Mobilization of bone Ca

Answer 9

PGE2 and PGI2

Question 10

Neutrophil activation

Answer 10

LTs

Question 11

Destabilization of basophils

Answer 11

PGD2

Question 12

Hypothalamic action to elevate normal body temp

Answer 12

PGE2

Question 13

Bronchoconstriction

Answer 13

PGD2, PGF2a, SRS-A

Question 14

Dysmenorrhea, contraction of uterine smooth muscle and vasculature

Answer 14

PGF2a

Question 15

Short-acting steroids

Answer 15

Cortisone

Hydrocortisone

Question 16

Intermediate-acting steroids

Answer 16

Prednisone
Prednisolone
Triamcinilone
Methylprednisolone

Question 17

Long-acting steroids

Answer 17

Dexamethasone

Bethamethasone

Question 18

Steroids adverse effects

Answer 18

1. Decreased Resistance to infection
2. Cataracts, Glaucoma
3. Electrolyte imbalance
4. Peptic ulcers
5. Adrenal suppression*
6. Loss of muscle mass
7. Osteoporosis*
8. Delayed Wound healing*
9. Hyperglycemia*
10. headoffemur necrosis
11. Incr. triglycerides
12. redistributed bodyfat
13. Diurnal rhythm upset*
14. Others