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Flashcards in Corynebacteria Deck (17)
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1
Q

Corynebacterium is gram _____ with a _____ shape and ______ arrangements

A

gram positive, pleomorphic rods with Palisade arrangements.

2
Q

Corynebacterium contains _____ bacteria which carries virulence genes

A

contains lysogenic bacteriophage

3
Q

Corynebacterium causes what type of infections?

A

Respiratory infection and also skin infections.

4
Q

Complications of Corynebacterium includes what?

A

throat swelling, constriction of airway (pseudomembrane).

5
Q

Diptheria is caused by what?

A

Corynebacterium diptheriae

6
Q

Death caused by Corynebacterium is _____% of respiratory cases

A

5-10% of respiratory cases

7
Q

How common is Corynebacterium diptheriae?

A

very rare now; about 0.001 cases per 100,000.

8
Q

How is Corynebacterium diptheriae spread?

A

direct physical contact of breathing the aerosolized secretions of infecte individuals.

9
Q

Is there an endemic of Corynebacterium?

A

yes in developing countries with low vaccination

10
Q

Prior to vaccinations in the 1920’s how many cases of corynebacterium diptheriae were there?

A

100-200 cases per 100,000 (mainly in children)

11
Q

What is the main virulence factor of corynebactrium?

A

AB type toxin is main virulence factor.

12
Q

What induces the toxin production of corynebacterium

A

Low iron

13
Q

Toxin AB can cause what?

A

myocarditis, polyneuritis (affects the peripheral nerves)

14
Q

What is used for treatment of Corynebacterium?

A

antitoxin

15
Q

What is the vaccine for corynebacterium?

A

DPT

16
Q

What is the test used for the diagnosis of Corynebacterium?

A

Elek test

17
Q

A fragment of toxin causes ____ and does what?

A

causes ADP- ribosylation in Elongation factor 2 dipthamide and halts the protein synthesis of host cell.