cours 2 Bourdineaud Flashcards

1
Q

définition stress oxydant

A

génération in vivo d’espèces réactives de l’oxygène (ERO)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

donner 4 EROS

A
  • O2-° = radical superoxyde
  • HO° = radical hydroxyde
  • HOOH = peroxyde d’hydrogène
  • ROOH = hydroperoxyde
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

donner 3 enzymes de neutralisation du stress oxydant (+ réaction)

A
  • superoxyde dismutase
  • catalase
  • gluthation peroxydase (indépendante et dépendante au sélénium)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

quelles sont les 3 types de super-oxyde dismutase

A
  • SOD1 = cytoplasmique (coeur catalytique Cu/Zn)
  • SOD2 = matrice mitochondriale (coeur catalytique Mn)
  • SOD3 = extracellulaire (coeur catalytique Cu/Zn)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

donner les deux sources de radicaux superoxyde

A
  • xanthine oxydase

- respiration mitochondriale ( ubiquinone réduite peut donner un radical semiquinone °QH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

peroxydation lipidique

A

malonaldéhyde

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

peroxydase réaction

A

2 schéma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

super oxyde dismutase réaction

A

schéma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

catalase réaction

A

schéma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

voie keap 1- NRF2

A

schéma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

ARE

A

antioxydant response element

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

structure tertiaire des MT

A

schéma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly