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CPJE SECRETS Flashcards

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1
Q

Veetids

A

penicillin VK

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2
Q

counseling points for penicillin VK

A

take on an empty stomach

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3
Q

Timentin

A

ticarcillin/clavulanic

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4
Q

Zosyn

A

piperacillin/tazobactam

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5
Q

Principen

A

ampicillin

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6
Q

Unasyn

A

ampicillin/sulbactam

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7
Q

Amoxil

A

amoxiciilin

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8
Q

Augmentin

A

amoxicillin/sulbactam

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9
Q

dosing frequency for amoxicillin

A

Q8-12H PO WITHOUT food

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10
Q

counseling points about augmentin

A
  • REFRIGERATE suspension
  • ok for 14 days at room temperature
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11
Q

DOC for acute otitis media, H. pylori & endocarditis

A

augmentin or amoxicillin

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12
Q

which penicillins covers PSA

A

ticarcillin/clavulanic [Timentin]
piperacillin/tazobactam [Zosyn]

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13
Q

extended spectrum PCNs are used for SSTIs, endocarditis, bone & joint ifx

A

naficillin [Nafcil, Nallpen] IV
oxacillin [Bactocill] IV
dicloxacillin [Dynapen] PO

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14
Q

Nafcil

A

nafcillin

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15
Q

Nallpen

A

nafcillin

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16
Q

Bactobil

A

oxacillin

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17
Q

Dynapen

A

dicloxacillin

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18
Q

penicillins clinical pearls

A
  • renal metabolism/renal toxicity
  • pregnancy category B
  • ↓effectiveness birth control
  • penicillin G salts [K, procaine, benzathine] are given by deep IM injection
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19
Q

which peniciilin G salts are given by deep IM inj?

A

K, procaine, benzathine

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20
Q

1st gen cephalosporins

A
  • cefadroxil [Duricef]
  • cefazolin [Ancef, Kefzol]
  • cephalexin [Keflex]
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21
Q

what are 1st gen cephalosporins used for

A

gram(+), SSTIs

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22
Q

Duricef

A

cefadroxil

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23
Q

cefadroxil dosing

A
  • 1-2 g Q12-24H PO
  • CrCl 30-50: 500mg Q12H
  • CrCl 10-30: 500mg Q24H
  • CrCl <10: 500mg Q36H
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24
Q

Ancef

A

cefazolin

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25
Kefzol
cefazolin
26
cefazolin dosing
- 1-2g Q8H IV/IM - CrCl 10-30: Q12H - CrCl <10: Q24H
27
Keflex
cephalexin
28
cephalexin dosing
- 250-500mg PO Q6H - CrCl 10-30: Q8-12H - CrCl <10: Q12-24H
29
2nd gen cephalosporins
- cefoxitin [Mefoxin] - cefprozil [Cefzil] - cefaclor [Ceclor] - cefuroxime [Ceftin, Zinacef]
30
what 2nd gen cephalosporins cover
gram (+)/(-), respiratory
31
Mefoxin
cefoxitin
32
Cefzil
cefprozil
33
Ceclor
cefaclor
34
Ceftin
cefuroxime
35
Zinacef
cefuroxime
36
cefoxitin dosing
- 1-2g Q4-6H IV/IM - CrCl 30-50: Q8-12H - CrCl 10-30: Q12-24H - CrCl <10L Q24-48H
37
cefprozil dosing
- 250-500mg PO Q12-24H - CrCl <30: 1/2 dose
38
cefaclor dosing
- 250-500mg PO Q8H - CrCl <10: 1/2 dose
39
cefuroxime dosing
- 0.25-1.5g IV/IM/PO Q8-12H - CrCl 10-30: Q12H - CrCl <10: Q24H
40
3rd gen cephalosporins
- cefdinir [Omnicef] - ceftazidime [Fortaz] - ceftriaxone [Rocephin] - cefotaxime [Claforan] - cefixime [Suprax]
41
Omnicef
cefdinir
42
Fortaz
ceftazidime
43
Rocephin
ceftriaxone
44
Claforan
cefotaxime
45
Suprax
cefixime
46
cefdinir dosing
- 300-600mg PO Q12-24H - CrCl 10-30: Q24H - CrCl <10: QOD
47
ceftazidime dosing
- 1-2g IV/IM Q8H - CrCl 30-50: Q12H - CrCl 10-30: Q24H - CrCl <10: 500mg Q24H
48
ceftriaxone dosing
- 1-2g IV/IM Q12-24H * no renal adjustments
49
cefotaxime dosing
- 1-2g IV/IM Q6-8H - CrCl <10: Q24H
50
cefixime dosing
- 200-400mg PO Q12-24H - CrCl 30-50: decrease by 25% - CrCl <30: decrease by 50%
51
4th gen cephalosporins
cefepime [Maxipime]
52
Maxipime
cefepime
53
cefepime dosing
- 0.5-2g IV/IM Q8H - CrCl <50: Q24H
54
5th gen cephalosporin
ceftaroline [Teflaro]
55
Teflaro
ceftaroline
56
ceftaroline dosing
- 400-600mg IV Q12H - CrCl 10-30: 300mg - CrCl <10: 200mg
57
which cephalosporins cover PSA
ceftazidime & cefepime
58
cephalosporins clinical pearls
- renal metabolism/toxicity [except ctx] - C.diff colitis - preg cat B - 1% cross sensitivity w/ PCNs → use 3rd gen
59
Zerbaxa
ceftolozane/tazobactam
60
Avycaz
ceftazidime/avibactam
61
which cephalosporins can be used for IAIs & UTIs
zerbaxa & avycaz - given IV
62
Fetroja
cefiderocol
63
what dose Fetroja cover
- siderophore cephalosporin for complicated UTIs - gram(-) coverage
64
what do carbapenems cover
- gram +/- & anaerobes - PSA except ertapenem
65
Primaxin
imipenem/cilastatin
66
Merrem
meropenem
67
Invanz
ertapenem
68
Doribax
doripenem
69
imipenem/cilstatin dosing
1g Q6H IV
70
meropenem dosing
2g IV/IM Q8H
71
ertapenem dosing
1g IV/IM QD
72
doripenem dosing
500mg IV Q8H
73
carbapenem clinical pearls
- renal metabolism/toxicity - risk of seizures - preg cat B → cat C for imipenem - allergic rxn rare in pts w/ rxn to pcn
74
Recarbio
imipenem/cilastatin/relebactam
75
what does Recarbio cover
- complicated UTIs or IAIs - combo with renal dehydropeptidase inhibitor & beta-lactamase inhibitor
76
what do monobactams cover
gram (-) PSA
77
monobactams
aztreonam [Azactam]
78
Azactam
aztreonam
79
aztreonam dosing
2g IV Q8H
80
monobactam clinical pearls
- renal dosing - ok w/ PCN allergy → safe alternative for allergic pts w/ nosocomial ifx
81
macrolides
- azithromycin [Zithromax, Z-Pak] - clarithromycin [Biaxin] - erythromycin [EES, Ery-tab, Erythrocin] - telithromycin [Ketek]
82
what do macrolides cover
- gram +/- - URI, chlamydia, atypicals, CAP, anaeroves - P450 blockers except azithromycin
83
Zithromax, Z-Pak
azithromycin
84
Biaxin
clarithromycin
85
EES, Ery-Tab, Erythrocin
erythromycin
86
Ketek
telithromycin
87
azithromycin dosing
- 500mg day 1 + 250mg days 2-5 - 500mg x3 days - no renal adjustment - tk w/ or w/o food → ER susp on EMPTY STOMACH
88
clarithromycin dosing
- 1g QD WITH FOOD - CrCl <30: 1/2 dose - causes metallic taste
89
erythromycin dosing
- 400mg PO QID w/ or w/o food - REFRIGERATE SUSP
90
telithromycin dosing
- 800mg PO QD
91
macrolide clinical pearls
- azithro & clarithro susp: DO NOT REFRIGERATE - QT prolongation [not telithro] - preg cat B: azithro & erythro - preg cat C: clarithro - SE: GI, cholestatic hepatitis [rare], allergies are rare
92
telithromycin clinical pearls
- CI: allergy to macrolides - BBW: DNU in myasthenia gravis [respiratory failure] - MedGuide → preg cat C - monitor visual adverse effects & loss of consciousness
93
lincosamide abx
clindamycin [Cleocin] gram(+)
94
Cleocin
clindamycin
95
clindamycin dosing
- 450mg PO TID-QID w/ or w/o food - 600-900mg IV Q6-8H
96
clindamycin clinical pearls
- BBW: C.diff colitis - preg cat B - do NOT refrigerate
97
fluoroquinolones abx
- ofloxacin [Floxin] - ciprofloxacin [Cipro] - delafloxacin [Baxdela] - levofloxacin [Levaquin] - moxifloxacin [Avelox, Vigamox] - gemifloxacin [Factive]
98
fluoroquinolones coverage
- gram +/- - atypicals
99
fluoroquinolones clinical pearls
- no need to take food - do NOT refrigerate - BBW: tendon rupture, peripheral neuropathy, CNS effects - photosensitivity → avoid skin sun exposure - hypoglycemia → check sugars - crystalluria → hydrate - seizures → avoid if seizure hx - c.diff diarrhea - QT prolongation - preg cat C → cartilage damage - interacts w/ multivalent cations → antacids, didanosine [Videx], iron, Zn, sucralfate [Carafate], resins, MV, dairy - inhibit CYP450 → increase INR - renal dose adjustments [except moxi] - gatifloxacin for eye infections only
100
FQ risk of QT prolongation
moxi > levo > cipro
101
Floxin
ofloxacin
102
Cipro
ciprofloxacin
103
Baxdela
delafloxacin
104
Levaquin
levofloxacin
105
Avelox, Vigamox
moxifloxacinF
106
Factive
gemifloxacin
107
which are respiratory FQs
levo, moxi, gemi
108
ofloxacin dosing
400mg Q12H PO/otic
109
which FQ is the most potent CYP inhibitor
cipro
110
ciprofloxacin dosing
- 200-400mg IV/opth/otic Q8H - 250-750mg PO BID or QD
111
delafloxacin dosing
- 300mg IV - 450mg PO - for SSTIs
112
levofloxacin dosing
- 500-750mg IV/PO/opth QD CrCl <50L - 750mg Q24H → Q48H - 500mg Q24H → 500mg x1 then 250mg Q24H - 250mg Q24H → no dose adjustment
113
moxifloxacin dosing
- 400mg Q24H IV/PO/opth - no renal dosing
114
gemifloxacin
- 320mg Q24H IV/PO
115
tetracyclines coverage
- atypicals, rickettsial, VRE - anthrax, syphilis, MRSA, lyme, rocky mountain spotted fever, skin & urinary ifx
116
tetracyclines abx
- doxycycline [Vibramycin/Doryx] - minocycline [Minocin, Dynacin, Solodyn] - tetracyclin [Sumycin] - tigecycline [Tygacil] - omadacycline [Nuzrya] → CAP & SSTIs - eravacycline [Xerava] → complicated IAIs
117
tetracyclines clinical pearls
- doxy: tk w/ food to decrease GI SE - all: tk w/ water to decrease GI, upright 30 min - photosensitivity - CI: children ≤8 [tooth discoloration] - preg cat D → avoid!! - interacts w/ multivalent cations - inhibits CYP450 → increases INR
118
Vibramycin
doxycycline
119
Doryx
doxycycline
120
Minocin
minocycline
121
Dynacin
minocycline
122
Solodyn
minocycline
123
Sumycin
tetracycline
124
Tygacil
tetracycline
125
Nuzyra
omadacycline
126
Xerava
eravacycline
127
doxycycline dosing
100mg Q12H
128
minocycline dosing
100mg Q12H
129
tetracycline dosing
500mg Q6H
130
tigecycline
100mg x1, then 50mg Q12H IV
131
Synercid
quinupristin/dalfopristin
132
synercid coverage
gram(+), MRSA, VRE
133
Synercid dosing
7.5mg/kg IV Q8H - no renal dose adjustment
134
Synercid clinical pearls
- D5W only - SE: hyperbilirubinemia, phlebitis, myalgias - volume must be ≥250mL to be given peripherally - CYP3A4 inhibitor
135
Cubicin
daptomycin
136
daptomycin coverage
- gram (+), MRSA, VRE - no pneumonia
137
daptomycin dosing
- 6mg/kg IV QD - adjust in renal dysfunction
138
daptomycin clinical pearls
- NS only - SE: rhabdomyolysis → monitor CPK, careful if pt n statin
139
Vibativ
telavancin
140
telavancin coverage
gram (+), MRSA
141
telavancin dosing
10 mg/kg IV QD - adjust in renal dysfunction
142
telavancin clinical pearls
- BBW: preg cat C → need preg test prior - 3A4/5 inhibitor & additive QT prolongation effects
143
Zyvox
linezolid
144
linezolid coverage
gram (+), MRSA, VRE
145
linezolid dosing
- 600mg Q12H PO/IV - trough: <2 ug/mL - peak: 12-26 ug/mL
146
linezolid clinical pearls
- do NOT refrigerate - SE: myelosuppression - MAOI → avoid tyramine foods, serotonergic drugs & adrenergic drugs [HTN crisis]
147
Flagyl
metronidazole
148
Tindamax
tinidazole
149
metronidazole & tinidazole coverage
- anaerobic - bacterial vaginosis, amoebiasis, giardiasis, trichomoniasis [anaerobes, protozoa]
150
metronidazole & tinidazole dosing
- 500mg Q6H PO/IV - TAKE WITH FOOD to prevent stomach upset
151
metronidazole & tinidazole clinical pearls
- SE: leukopenia, neutropenia, metallic taste, furry tongue, darkened urine, disulfiram-like rxn w/ alcohol - most serious SE: CNS & convulsive seizures - monitor: CBC, WBC w/diff - preg cat B - CYP2C9 inhibitor → increase INR & decrease birth control effect - do NOT refrigerate IV form [crystals]
152
abx w/ narrow therapeutic window monitoring
- peak: 30 min after infusion [2-3 hour for vanco] - trough: before next dose
153
abx w/ narrow therapeutic window
- AMGs - vanco - chloramphenicol
154
aminoglycosides
- gentamicin - tobramycin - amikacin
155
AMG coverage
- gram(-) → PSA, E. coli, klebsiella
156
gentamicin & tobramycin dosing
2 mg/kg/dose IV Q8H
157
gentamicin & tobramycin peak & trough goals
peak: ≤10 mcg/mL trough: <2 mcg/mL
158
AMGs clinical pearls
- BBW: neuro/nephro/ototoxicity - nephro is reversible - oto is irreversible - preg cat C/D
159
amikacin dosing
7.5mg/kg/dose IV Q8H
160
amikacin peak & trough goals
peak: ≤30 mcg/mL trough: <5 mcg/mL
161
Zemdril
plazomicin
162
Vancocin
vancomycin
163
vancomycin coverage
PO for C.diff IV for MRSA
164
vancomycin dosing
- 15mg/kg or 500mg-2g/day divided Q6-12H - dilute to max 5mg/mL - CrCl 40-79: Q24H - CrCl 25-39: Q48H - CrCl <25: check trough
165
vancomycin peak & trough goals
peak: ≤40 mcg/mL [>80 mcg/mL is toxic] trough: <10 mcg/mL [20 for severe ifx]
166
vancomycin clinical pearls
- nephro/ototoxicity - DNU w/ other nephro/ototoxic drugs → MAGs, ampB - rates >15mg/min = red man syndrome - preg cat C
167
chloramphenicol clinical pearls
- BBW: blood dyscrasias → can induce rare and irreversible bone marrow suppression - must monitor CBC - SE: gray syndrome of neonates
168
UTI trx
1. fosfomycin [Monurol] 2. sulfamethoxazole & trimethoprim [Bactrim, Septra] 3. nitrofurantoin [Macrobid, Macrodantin] others: - fluoroquinolones → cipro or levo - beta-lactams [less efficacy] → amoxil, augmentin, keflex, rocephin - methenamine [UREX]
169
UTI ppx
- methenamine [UREX] → to prevent recurrent UTIs - cranberry juice may potentially prevent
170
UTI symptoms trx
phenazopyridine [Azo, Uristat, Pyridium] - urinary analgesic
171
UTI trx for pregnant pts
- treat for 7 days to prevent premature birth - beta-lactams & fosfomycin - nitrofurantoin ok before 37 weeks - phenazopyridine for symptoms
172
Monurol
fosfomycin
173
Bactrim/Septra
SMX/TMP
174
Macrobid
nitrofurantoin monohydrate macrocrystal
175
Macrodantin
nitrofurantoin macrocrystal
176
fosfomycin dosing
3g x1
177
fosfomycin clinical pearls
diarrhea
178
SMX/TMP dosing
- SS: 400mg SMX/80mg TMP - DS: 800mg SMX/160mg TMP [5:1 ratio] - adults: DS tab BID
179
SMX/TMP clinical pearls
- take with food - caution w/ sulfa allergy - preg cat C - do NOT refrigerate - short stability [6 H] - protect from light when undiluted - D5W only!! - crystalluria → hydrate to prevent kidney stones - photosensitivity - 2C8/9 inhibitors → increases INR - serious skin rashes - watch for blood dyscrasias - don't give in G6PD deficiency - adjust dose for CrCl <30 mL/min
180
nitrofurantoin clinical pearls
- take with food - interacts with Mg antacids - dark urine color - serious lung problems & C.diff - preg cat D near term
181
nitrofurantoin dosing
macrobid: 100mg BID macrodantin: 100mg QID
182
methanamine clinical pearls
- 1g BID - avoid alkalinizing foods/meds - urinary antiseptic - monitor liver function - preg cat C
183
phenazopyridine clinical pearls
- 200mg TID [Rx] - 100mg TID [OTC] x2 days - urinary analgesic - Azo dye → red-orange urine
184
latent TB trx
- INH + rifapentine once weekly x3 months - rifampin QD x4 months - INH + rifampin QD x3 months
185
active TB trx
- rifampin + INH + pyrazinamide + ethambutol x26 weeks [initial phase] - rifampin + pyrazinamide + ethambutol +/- FQ x6 months [if resistance to INH] - INH + ethambutol + FQ + pyrazinamide [x 2mo] x12-18 mo → if resistance to RIF
186
drug-resistant TB abx
pretomanid
187
isoniazid clinical pearls
- hepatoxic - tk on empty stomach - BBW: fatal hepatitis - neurotoxic → add Vit B6 [pyridoxine] to prevent neuropathy - lupud/flu-like symptoms - P-450 inhibitor
188
Rifadin
rifampin
189
Priftin
rifapentine
190
Myambutol
ethambutol
191
rifampin clinical pearls
- orange urine/body fluids - flu-like syndrome - CYP3A4 inducers → decreased bioavailability & increased clearance of coadministered meds [decrease efficacy of oral contraceptives]
192
rifapentine clinical pearls
- orange urine/body fluids - allergy rxn & flu-like syndrome - decreased WBC & RBC!! - CYP3A4 inducers → decreased bioavailability & increased clearance of coadministered meds [decrease efficacy of oral contraceptives]
193
ethambutol clinical pearls
- optic neuritis → monthly vision tests
194
Amphocin
amp B infusion - for life-threatening fungal ifx
195
Abelcet
ampB lipid complex
196
AmBisome
liposomal ampB
197
ampB clinical pearls
- preg cat B - decreased K+ → enhances digoxin toxicity - decreased Mg2+ - nephrotoxicity → DNU w/ cyclosporin, AMGs, flucytosine, cisplatin - D5W only - pre-medicate for infusion-related rxn
198
Ancobon, 5-FC
flucytosine
199
flucytosine clinical pearls
- converts to fluorouracil - causes bone marrow suppression - avoid monotherapy d/t rapid resistance
200
Cancidas
caspofungin
201
caspofungin dosing
500mg IV QD NS only!!!
202
Mycamine
micafungin
203
mycamine dosing
100mg IV QD
204
azole antifungals
- ketoconazole [Nizoral] - fluconazole [Diflucan] - itraconazole [Sporanox] - voriconazole [Vfend] - posaconazole [Noxafil] - isavuconazonium [Cresembra]
205
Nizoral
ketoconazole
206
Diflucan
fluconazole
207
Sporanox
itraconazole
208
Vfend
voriconazole
209
Noxafil
posaconazole
210
Cresemba
isavuconazonium
211
ketoconazole dosing
400mg QD
212
ketoconazole clinical pearls
- BBW: hepatotoxicity - need acidic pH for absorption → avoid using with antacids, H2RAs, PPIs
213
fluconazole dosing
400mg QD
214
fluconazole IV to PO
IV:PO = 1:1
215
fluconazole clinical pearls
- single dosing: 150mg tab x1 - if taken longer, counsel on possible hepatotoxicity or serious skin rash
216
itraconazole dosing
400mg QD
217
itraconazole clinical pearls
- BBW: heart failure - note: oral caps & oral sol → CANNOT use interchangeably - caps need food [gastric acidity] for absorption - sol can take on empty stomach - need acidic pH for absorption → avoid antacids, H2RAs, PPIs
218
Mycostatin
Nystatin
219
oral yeast ifx trx
- Rx only!! - TOP: nystatin susp 4-5x daily [swish & swallow] or clotrimazole lozenges - PO: fluconazole or itraconazole
220
Mycelex
clotrimazole
221
vaginal candida ifx trx
PO [Rx]: - fluconazole 150mg PO x1 [can repeat] and itraconazole → increased resistance from azoles - ibrexafungerp [Brexafemme] 150mg - 2 pills AM & 2 pills PM INTRAVAGINAL/TOP [OTC]: 1, 3, 7(14) day regimens - safe for pregnancy - clotrimazole [Gyne-Lotrimin-7, Mycelex-7]: 1% cream x7 days, supp 100mg x7 days - miconazole [Monistat-1, Monistat-3, Monistat-7]: supp 1.2g x1, 200mg x3 days or 100mg x7 days - nystatin vaginal insert [Mycostatin]: 100,000 units QD x14 days - butoconazole [Femstat-3, Gynazole-1]: 2% cream 5g x1-3 days - tioconazole [Vagistat-1]: 6.5% oint 5g x1 - terconazole cream [Terazol]: 0.4% cream x7 days, 0.8% cream x3 days, supp [Zazole] 80mg x3 days
222
Brexafemme
ibrexafungerp
223
Gyne-Lotrimin-7, Mycelex-7
clotrimazole
224
Monistat
miconazole
225
Mycostatin
nystatin vaginal insert
226
Femstat-3, Gynazole-1
butoconazole
227
Vagistat-1
tioconazole
228
Terazol
terconazole cream
229
Zazole
terconazole supp
230
HSV-1 vs HSV-2
HSV-1: oropharyngeal [cold sores or fever blisters] HSV-2: genital
231
HSV trx
- Rx: acyclovir [Zovirax], valacyclovir [Valtrex], penciclovir [Denavir] - works best taken at 1st sign of outbreak within 1st day - PO: 200mg 2-5 times QD [drink lots of fluid] - cream: 6 times/day x7 days - valacyclovir: 2g BID x1 day for herpes labialis - use foscarnet if resistant to acyclovir/valacyclovir/famciclovir
232
cytomegalovirus trx
- ganciclovir [Cytovene, Cymevene, Vitrasert ocular] - valganciclovir [Valcyte] - cidofovir [Vistide] - foscarnet [Foscavir]
233
which abx has been clinically shown to decrease effectiveness of birth control pills
rifampin
234
abx for PSA
- AMGs - beta-lactams: cefepime, ceftazidime, zosyn, ticarcillin-clavulanate - aztreonam - carbapenems: imi, mero, dori - FQ: cipro, levo
235
abx during pregnanct
- beta-lactams: PCNs, cephalosporins & carbapenems [no imi] - clindamycin - macrolides: azithro, erythro [NO claritho] - flagyl ok for bacterial vaginosis or vaginal trichomoniasis
236
oral abx susp that should not be refrigerated
- azithromycin - clarithromycin - clindamysin - FQs - voriconzole
237
C.diff ifx trx
- vanco PO [Firvanq] 125mg QID [500mg QID with flagyl IV if severe/complicated] AND/OR - fidaxomicin [Dificid] 200mg tab BID x10 days - alt: flagyl - bezlotoxumab [Zinplava]: human mAb that neutralized effect of C.diff → 10 mg/kg IV x1 w/ abx
238
abx ped dosing
- amox: 50mg/kg [max 2g]; susp = 50mg/mL PCN allergy: - clindamycin 20mg/kg [max 600mg] - azithromycin 15mg/kg [max 500mg] - clarithromycin 15mg/kg [max 500mg]
239
Zovirax
acyclovir
240
Valtrex
valacyclovir
241
Denavir
penciclovir
242
Famvir
famciclovir
243
Cytovene, Cymevene
ganciclovir
244
Vitrasert
ganciclovir ocular
245
Valcyte
valganciclovir
246
Vistide
cidofovir
247
Foscavir
foscarnet
248
Firvanq
vanco PO
249
Dificid
fidaxomicin
250
Zinplava
bezlotoxumab
251
malaria ppx regimen
start 1-2 days prior to travel & continue QD until 7 days after travel - atovaquone-proguanil [Malarone] - primaquine: CI w/ G6PD deficiency need to be taken for 4 weeks after travel: - chloroquine [weekly]: if on hydroxychloroquine, don't need additional meds - mefloquine [Lariam]: weekly; CI in neuro/psych disorders - doxycycline: daily
252
malaria trx regimen
chloroquine-resistant: - atovaquone-proguanil [Malarone] x3 days - artemether-lumefantrine [Coartem] x3 days - quinine x3-7 days PLUS doxy, tetra or clinda x7 days - mefloquine [Lariam] - sulfadoxine-pyrimethamine [Fansidar] chloroquine-sensitive: - chloroquine [Aralen]: 600mg base PO + 300mg base PO at 6, 24, 28 hours - hydroxychloroquine [Plaquenil] - primaquine severe malaria: - artesunate IV then malarone, doxy [clinda if preg] or mefloquine pregnant: - chloroquine phosphate OR hydroxychlorouine, quinine + clinda, OR mefloquine - tafenoquine [Krintafel] for prevention of relapse of p. vivax ifx
253
quinine clinical pearls
- SE: cinchonism - overdosage may lead to cardiotoxicity - monitor for hypoglycemia
254
sulfadoxine-pyrimethamine clinical pearls
- SE: bone marrow suppression, hemolysis with G6PD deficiency - sulfa allergy
255
hydroxychloroquine clinical pearls
- SE: toxicity in eye w/ chronic use
256
Malarone
atovaquone-proguanil
257
Lariam
mefloquine
258
Coartem
artemether-lumefantrine
259
Fansidar
sulfadoxine-pyrimethamine
260
Aralen
chloroquine
261
Plaquenil
hydroxychloroquine
262
Krintafel
tafenoquine
263
normal BP
<120/80 mmHg
264
elevated BP
SBP 120-129 AND DBP <80
265
stage 1 HTN
SBP 130-139 OR DBP 80-90
266
stage 2 HTN
SBP ≥140 OR DBP ≥90
267
thiazide diuretics clinical pearls
- diuretics of choice → if NO renal impairment - SULFA drugs → photosensitivity rash - metolazone ok if renal dysfunction
268
Diuril
chlorothiazide
269
Microzide
HCTZ
270
Hydrodiuril
HCTZ
271
Dyazide
HCTZ + triamterene
272
Maxzide
HCTZ + triamterene
273
Thalidone
chlorthalidone
274
Hygroton
chlorthalidone
275
Zaroxolyn
metolazone
276
Lozol
indapamide
277
chlorothiazide target dose
500mg
278
HCTZ target dose
50mg
279
chlorthalidone target dose
25mg
280
metolazone target dose
20mg
281
indapamide target dose
2.5mg
282
which diuretics cause metabolic alkalosis
thiazides & loops
283
which diuretics cause metabolic acidosis
K+ sparing & aldosterone antagonists
284
metabolic alkalosis
decrease: - K+ [hypokalemia] - Na+ [hyponatremia] - Mg2+ increase: - BG, TG, TC, UA monitor: diabetes & gout thiazides: increase Ca2+ loops: decrease Ca2+ [decrease bone density]
285
Lasix
furosemide
286
Demadex
torsemide
287
Bumex
bumetanide
288
Edecrin
ethacrynic acid
289
loop diuretics clinical pearls
- SULFA drugs → photosensitivity, rash - diuretics of choice if renal disease - increase fluid depletion → for edema in HR & need K+ supp - IV is light sensitivity & can cause ototoxicity - Edecrin: avoid with AMGs
290
furosemide target dose
40mg BID
291
bumetanide target dose
1mg BID
291
torsemide target dose
10mg QD
292
ethacrynic acid target dose
25-50mg ok for sulfa allergy
293
oral loop dose equivalency
furo 40mg = tor 20mg = bume 1mg
294
Dyrenium
triamterene
295
triamterene target dose
300mg
296
Midamor
amiloride
297
amiloride target dose
20mg
298
aldosterone antagonists clinical pearls
- SE: gynecomastia [spironolactone only] - for HF & HTN - CI in pregnancy - tk spironolactone w/ food
299
Aldactone
spironolactone
300
Carospir
spironolactone
301
Inspra
eplerenone
302
spironolactone target dose
25-50mg
303
eplerenone target dose
25-50mg
304
metabolic acidosis
- monitor: increased K+, decreased Ca2+, gout - CI if CrCl <30 mL/min
305
ACE-I & ARB clinical pearls
- BBW: CI in pregnancy & bilateral renal artery stenosis [drops glomerular perfusion pressure] - metabolic acidosis - can increase K+ - AE: dry cough [mainly ACE-I], HA, dizziness, angioedema [esp black pts] - well tolerated, no need to take w/ food - monitor renal function → 1st line in CKD bc antihypertensive & anti-inflammatory - avoid combo w/ NSAIDs
306
why can't lithium be given with diuretics
diuretics decrease lithium's renal clearance & increase toxicity
307
what can licorice cause in large amounts
increase BP, salt and water retention, & decrease K+ levels
308
Lotensin
benazepril
309
Capoten
captopril
310
Vasotec
enalapril
311
Enalaprilat
injectable enalapril
312
Monopril
fosinopril
313
Zestril
lisinopril
314
Prinivil
lisinopril
315
Prinzide
lisinopril + HCTZ
316
Zestorectic
lisinopril + HCTZ
317
Univasc
moexipril
318
Accupril
quinapril
319
Altace
ramipril
320
Mavik
trandolapril
321
target dose of benazepril
40mg
322
target dose of captopril
50mg TID
323
target dose of enalapril
40mg
324
target dose of fosinopril
40mg
325
target dose of lisinopril
40mg
326
target dose of moexipril
30mg
327
target dose of quinapril
40mg
328
target dose of ramipril
10mg
329
trandolapril
4mg
330
Atacand
candesartan
331
Teveten
eprosartan
332
Avapro
irbesartan
333
Avalide
irbesartan + HCTZ
334
Cozaar
losartan
335
Hyzaar
losartan + HCTZ
336
Diovan
valsartan
337
Benicar
olmesartan
338
Micardis
telmisartan
339
Edarbi
azilsartan
340
candesartan target dose
32mg
341
eprosartan target dose
800mg
342
irbesartan target dose
300mg
343
losartan target dose
100mg
344
valsartan target dose
320mg
345
olmesartan target dose
40mg
346
telmisartan target dose
80mg
347
azilsartan target dose
80mg
348
what are beta-blockers CI in
- diabetes - asthma & COPD - bradycardia - heart block - caution in unstable F & peripheral vascular disease
349
beta-blockers side effects
- dyslipidemia & weight gain - fluid retention - fatigue, depression, decreased libido - dizziness → tk w/ food - don't d/c abruptly
350
beta-blocker indications
- HTN → 2nd line - post-MI - angina - tachyarrhythmias - stable HF - migraine & glaucoma
351
cardioselective beta-blockers
beta-1 selective [excitatory heart] BE A MAN
352
Tenormin
atenolol
353
Tenoretic
atenolol + chlorthalidone
354
Lopressor
metoprolol tartrate IR
355
Toprol
metoprolol succinate ER
356
Brevibloc
esmolol → IV for HTN emergency
357
Zebeta
bisoprolol
358
Ziac
bisoprolol + HCTZ
359
Kerlone
betaxolol
360
Betoptic
betaxolol for glaucoma
361
Sectral
acebutolol
362
Bystolic
nebivolol → increases nitric oxide production
363
max dose of atenolol
100mg
364
max dose of metoprolol
- 25-200mg - HTN: 400mg/d - HF: HF 200mg/d
365
max dose of bisoprolol
10mg
366
max dose of betaxolol
40mg
367
max dose of acebutolol
400mg BID
368
max dose of nebivolol
40mg
369
non-selective beta-blockers
- b-1 & b-2 blockers - b-2: bronchodilators
370
Inderal LA, InnoPran
propranolol → tk w/ food
371
propranolol max dose
IR 80mg BID ER QD
372
Blocadren
timolol
373
Timoptic
timolol → glaucoma
374
timolol max dose
40mg BID
375
Visken
pindolol
376
pindolol max dose
40mg BID
377
Corgard
nadalol
378
nadalol max dose
320mg
379
Levatol
penbutolol
380
penbutolol max dose
80mg
381
Cartrol
carteolol
382
carteolol max dose
10mg
383
Ocupress
carteolol → glaucoma
384
Normodyne
labetalol → tk w/ food
385
Trandate
labetalol → tk w/ food
386
labetalol max dose
800mg BID [2400mg/d]
387
Coreg
carvedilol → tk w/ food
388
carvedilol max dose
IR: 50mg BID ER: 80mg QD 3.125-6.25-12.5-25mg tabs
389
Cardizem
diltiazem
390
Calan
verapamil
391
Isoptin
verapamil
392
Verelan
verapamil
393
Covera
verapamil
394
non-DHP CCB clinical pearls
- more negative inotropic effects → BRADYCARDIA - CI in 2-3rd AV block, acute MI, BB use - effective for arrhythmias - preferred for CKD & diabetic nephropathy - SE: gingival hyperplasia, constipation - CYP3A4 DDIs
395
DHP CCB clinical pearls
- more potent vasodilators → reflex TACHYCARDIA - ok with BBs but CI if acute mI - ineffective for arrhythmias - SE: HA, flushing, edema of ankle - no significant DDIs
396
Norvasc
amlodipine
397
Katerzia
amlodipine PO susp
398
Lotrel
amlodipine + benazepril
399
Exforge
amlodipine + valsartan
400
Azor
amlodipine + olmesartan
401
Plendil
felodipine ER
402
DynaCirc
isradipine CR
403
Cardene
nicardipine
404
Adalat CC
nifedipine ER
405
Procardia XL
nifedipine ER
406
Sular
nisoldipine
407
alpha-1 blockers clinical pearls
- syncope d/t orthostatic HoTN after initial dose, dizziness, fatigue - titrate - mainly for BPH - for HTN: doxazosin, terazosin, prazosin
408
Cardura
doxazosin
409
Hytrin
terazosin
410
Minipress
prazosin
411
Flomax
tamsulosin
412
Uroxatral
alfuzosin
413
Rapaflo
Silodosin
414
alpha-2 agonist clinical pearls
- caution: bradycardia, dry mouth, fatigure, depression, psychotic rxn, impotence, rebound HTN - clonidine for resistance HTN & pts who can't swallow - clonidine off-label for opioid withdrawal, anxiety & sleep - methyldopa SE: lupus-like symptoms, hepatitis, myocarditis, hemolytic anemia
415
Catapres
clonidine
416
clonidine dosing
- 0.1-0.3mg BID - patch is weekly
417
Aldomet
methyldopa
418
methyldopa dosing
500mg BID [max 3000mg/day]
419
Wytensin
guanabenz
420
Tenex
guanfacine
421
direct vasodilators clinical pearls
- caution: reflex tachycardia - hydralazine: lupus like symptoms - minoxidil: hair growth
422
adrenergic neuron blockers clinical pearls
- caution: bradycardia, depression
423
Apresoline
hydralazine
424
Loniten
minoxidil
425
Serpasil
Reserpine
426
reserpine dosing
0.05-0.25mg
427
IV agents for hypertensive crisis
- hydralazine - NTG [Tridil] → absorbs into plastic, DNU PVC - labetalol, esmolol - enalaprilat - clonidine - phentolamine [Regitine] - nitroprusside [Nipride] → most effective - nicardipine
428
HTN in pregnancy
- 1st line: methyldopa & labetalol - 2nd line: hydralazine, nifedipine & BBs
429
STEMI trx
- fibrinolysis [<30 min or when can't do PCI within 90 min] - primary PCI [<90 min] → angioplasty or stent - LD: P2Y12-i
430
NSTEMI & UA trx
- MONA - IV anti-thrombotics → GPIIb/IIIa-i, antiplatelets [P2Y12-i], anticoagulants [heparin, LMWH]
431
t-PA, Activase
alteplase
432
r-RA, Retavase
reteplase
433
TNK-tPA
tenecteplase
434
Streptase
streptokinase
435
Abbokinase
urokinase
436
Reopro
abciximab
437
conversion between carvedilol IR and ER
Coreg CR 10mg QD = Coreg 3.125mg BID Coreg CR 20mg QD = Coreg 6.25mg BID Coreg CR 40mg QD = Coreg 12.5mg BID Coreg CR 80mg QD = Coreg 25mg BID
438
ACS discharge meds
- aspirin 81mg indefinitely - DAPT w/ P2Y12-i for ≥1 year - + warfarin if persistent AF - ACE-I/ARB if LVEF <40% - beta-blocker - statin is LDL >100 - NTG
439
Aggrastat
tirofiban
440
Integrilin
eptifibatide
440
Ticlid
ticlopidine
440
Plavix
clopidogrel
440
Effient
prasugrel
441
Kengreal IV
cangrelor
442
IV antithrombotics
- abciximab [Reopro] - tirofiban [Aggrastat] - eptifibatide [Integrilin]
443
abciximab clinical pearls
- PCI only - NOT reversible - dose: 0.25mg/kg bolus before PCI Then 0.125mcg/kg/min x12 hours - ADE: thrombocytopenia, bleeding & HoTN - monitor: Hct/hgb, platelets, PT/aPTT, ACT - not renally adusted
443
Brilinta
ticagrelor
444
tirofiban clinical pearls
- ACS - reversible - dose: 0.4 mcg/kg/min x30 min then 0.1mcg/kg/min x24 H after PCI - ADE: thrombocytopenia, bleeding & HoTN - monitor: Hct/hgb, platelets, PT/aPTT, ACT - renally adjust
444
which P2Y12-i is only indicated for PCI
prasugrel
444
eptifibatide clinical pearls
- ACS + PCI - reversible - dose: 180 mcg/kg bolus then 2mcg/kg/min x24H - protect from light, refrigerate - ADE: thrombocytopenia, bleeding & HoTN - monitor: Hct/hgb, platelets, PT/aPTT, ACT - renally adjusted
444
irreversible P2Y12-is
- clopidogrel - ticlopidine - prasugrel
445
clopidogrel dosing
LD: 300-600mg MD: 75mg QD
445
reversible P2Y12-is
- cangrelor - ticagrelor
445
prasugrel dosing
LD: 60mg MD: 10mg QD
445
when do antithrombotics have to be d/c'ed before surgery
5-7 days
445
ticagrelor dosing
LD: 180mg LD MD: 90mg BID
446
Jantoven
warfarin
446
Coumadin
warfarin
447
Pradaxa
dabigatran DTI
447
Bevyxxa
betrixaban Factor Xa inhibitor
448
Innohep
Tinzaparin LMWH
448
warfarin clinical pearls
- BBW: fatal bleeding, skin necrosis, purple toe, DDIs - hepatically cleared - preg cat X - reversal: vit K, PCC, frozen plasma
448
Eliquis
apixaban Factor Xa inhibitor
449
heparin clinical pearls
- SC for ppx - IV for trx - no renal adjustment - reversal: protamine
449
Andexxa
Andexanet-alfa
449
LMWH clinical pearls
- no routine monitoring - lovenox trx: 1mg/kg SC BID - lovenox ppx: 40mg SC QD - renally adjusted - reversal: protamine
449
fondaparinux clinical pearls
- ppx: 2.5mg SC - trx: 5-10mg SC - no routine monitoring - renal adjustment → CI if CrCl <30 - reversal: Andexxa
450
Praxbind
idarucizumab
451
edoxaban clinical pearls
- 60mg PO QD - no routine monitoring - renal adjust → 30mg QD - stroke ppx in NVAF, DVT/PE - reversal: andexxa
451
warfarin colors
1mg - pink 2mg - lavender 2.5mg - green 3mg - brown 4mg - blue 5mg - peach 6mg - teal 7.5mg - yellow 10mg - white
451
xarelto clinical pearls
- dose: 20mg PO QD - renal adjust → 15mg QD - for stroke ppx in nonvalvular AFib, DVT/PE, surgical ppx
451
what can increase INR
- ginger - gingko - garlic - anti-inflammatory agents - antibiotics - antidepressants - antiplatelets - azoles - CYP2C9 inhibitors
452
what can decrease INR
- ginseng - green tea - soya - SJW - vit K - CYP2C9 inducers
453
class I antiarrhythmias
*PROLONG QT INTERVAL - quinidine - procainamide - disopyramide
453
antithrombotic for Afib
- dabigatran - rivaroxaban - apixaban - warfarin
453
rate controllers for afib
- beta-blockers - non-DHP CCBs - digoxin
453
Norpace
disopyramide
453
quinidine clinical pearls
- tk w/ food to decrease GI upset - BBW: increased mortality. thrombocytopenia [monitor CBC] - SE: diarrhea, strong anticholinergic → cinchonism - DDIs: digoxin [decrease digoxin 50%], warfarin [increase INR]
454
Fragmin
dalteparin LMWH
454
Lovenox
enoxaparin LMWH
454
Arixtra
fondaparinux Factor Xa inhibitor
454
Xarelto
rivaroxaban Factor Xa inhibitor
455
Savaysa
edoxaban Factor Xa inhibitor
456
class II antiarrhythmics
beta-blockers - esmolol - propranolol
457
Cordarone
amiodarone
457
Tikosyn
dofetilide
457
class III antiarrhythmics
*INCREASE QT INTERVAL - amiodarone - dofetilide - dronedarone - ibutilide - sotalol
457
Multaq
dronedarone
458
Corvert
ibutilide
459
amiodarone clinical pearls
- broad spectrum antiarrhythmic, safe in HR & post MI - only for life-threatening arrhythmias - D5W only - SE: vision changes/corneal microdeposits, photosensitivity, HoTN, bradycardia, dizziness, tremor, slate blue skin - monitor thyroid, liver, lungs - use lower doses of digoxin, warfarin, quinidine, procainamide, simvastatin, lovastatin, atorvastatin
459
class IV antiarrhythmics
non-DHP CCBs - verapamil - diltiazem
459
Adenocard
adenosine
459
Betapace
sotalol
460
Lanoxin
digoxin
461
digoxin therapeutic range for AF
0.5-2 ng/mL
461
Digitek
digoxin
461
digoxin therapeutic range for HF
0.5-0.9 ng/mL
461
drugs that increase QT
- class Ia antiarrhythmics - class III antiarrhythmics - quinolones - macrolides - amantadine - foscarnet - azoles - PIs - APs, SSRIs, TCAs, SNRIs, trazodone - 5-HT3 inhibitors & droperidol - alfuzosin - apomorphine - chloroquine - galantamine - methadone - pentamidine
462
angina trx
- aspirin - antianginal: beta-blockers, CCBs [Prinzmetal], nitrates, ranolazine
463
Nitro-Bid
NTG ointment 2%
463
Nitro-Dur
NTG patch
463
Minitran
NTG patch
464
Tridil
NTG IV → D5W
464
NitroMist
NTG spray
465
Nitrostat
NTG sublingual tab
465
Monoket
isosorbide mononitrate IR
465
Nitrolingual
NTS spray
465
Ismo
isosorbide mononitrate IR
465
Nitro-Time
NTG extended release
466
Dilatrate-SR
isosorbide dinitrate - decrease mortality in HF
466
Imdur ER
isosorbide mononitrate ER
466
Ranexa
ranolazine
466
Isordil
isosorbide ditrate - decreases mortality in HF
467
HF trx
- 1st line: ARNI/ACE-I/ARB + beta-blocker + MRA + SGLT2-i - hydralazine + isosorbide dinitrate 1st line in african americans - diuretics as needed - additional: ivabradine, vericiguat, digoxin, potassium binder, digoxin
468
procainamide clinical pearls
- tk on empty stomach - BBW: agranulocytosis
468
disopyramide clinical pearls
- tk on empty stomach - SE: HF, anticholinergic effects
468
class Ib antiarrhythmics
- lidocaine - mexiletine
468
Xylocaine
lidocaine
468
class Ic antiarrhythmics
- flecainide - propafenone *not in use
469
which statins do you take at bedtime
fluva, lova ER & simva
470
lipophilic statins
atorva, lova, simva, fluva, pitava - higher risk for muscle pain
470
Mevacor IR
lovastatin IR → tk with dinner
470
Lescol
fluvastatin
471
Altoprev ER
lovastatin ER → tk QHS
471
hydrophilic statins
rosu, prava - lower risk for muscular side effects
472
Lipitor
atorvastatin
472
Pravachol
pravastatin
472
Zocor
simvastatin → tk QHS
472
Crestor
rosuvastatin
472
Livalo
Pitavastatin
473
Niacor
niacin OTC → tk w/ food
473
Niaspan ER
niacin ER → tk QHS after low-fat snack
473
Nexletol
bempedoic acid ATP citrate lyase inhibitor
473
Juxtapid
lomitapide MTTP inhibitor
473
Evkeeza
evinacumab-dgnb angiopoietin-like 3 inhibitor
474
Nexlizet
bempedoic acid/ezetimibe ATP citrate lyase inhibitor
474
Zetia
ezetimibe
474
Colestid
colestipol bile-acid binding resins
474
Vytorin
ezetimibe + simvastatin
474
Welchol
colesevelam bile-acid binding resins
474
Questran, Prevalite, LoCholest
cholestyramine bind-acid binding resins
475
Tricor
fenofibrate
475
Lopid
gemfibrozil → better not w/ statins
475
Lipofen
fenofibrate
475
Trilipix
fenofibrate
476
Repatha
evolocumab PCSK9-i mAb
476
Leqvio
inclisiran siRNA
476
Praluent
alirocumab PCSK9-i mAb
476
Antara
fenofibrate
477
Humalog
insulin lispro rapid-acting
477
Triglide
fenofibrate
478
Corlanor
ivabradine
478
Verquvo
vericiguat
478
antidote for digoxin
Digibind or Digifab
478
what is tafamadis indicated for
transthyretin amyloid → reduce CV morbidity & mortality
479
lipid panel goals
LDL <100 TG <15 HDL ≥60 TC <200
480
cholesterol guidelines
- statins 1st line - pts w/ clinical ASCVD: high-intensity statin - high-intensity statin: lipitor 40-80mg & crestor 20-40mg
481
Lyumjev
insulin lispro rapid-acting
481
Novolog
insulin aspart rapid-acting
481
Fiasp
insulin aspart rapid-acting *has niacinamide
482
Admelog
insulin lispro rapid-acting
483
Apidra
insulin glulisine rapid acting
483
Humulin R
insulin regular short-acting
484
Ozempic
semaglutide GLP-1 agonist
484
Rybelsus
semaglutide PO GLP-1 agonust
484
Novolin R
insulin regular short-acting
485
Januvia
sitagliptin DPP4-i
485
Onglyza
saxagliptin DPP4-i
486
Tradjenta
linagliptin DPP4-i
486
Micronase
glyburide SU
486
Diabeta
Glyburide SU
486
Glucotrol
glipizide SU
486
Amaryl
glimepiride SU
487
Prandin
repaglinide meglitinide
488
Starlix
nateglinide meglitinide
488
Actose
pioglitazone TZD
488
Fortamet
metformin
488
Avandia
rosiglitazone TZD
488
Glucophage
metformin
489
Precose
acarbose alpha-glucosidase inhibitor
489
Glumetza
metformin
489
Farxiga
dapagliflozin SGLT2-i
489
Invokana
canagliflozin SGLT2-i
489
Glyset
miglitol alpha-glucosidase inhibitor
490
Steglatro
ertugliflozin SGLT2-i
491
Xigduo XR
dapagliflozin + metformin
491
Segluromet
ertugliflozin + metformin
491
Invokamet
canagliflozin + metformin
491
Jardiance
empagliflozin SGLT2-i
491
Kazano
alogliptin + metformin
492
Glyxambi
empagliflozin + linagliptin
492
Kerendia
finerenone nonsteroidal MRA
492
Oseni
alogliptin + pioglitazone
492
Lyxumia
lixisenatide
493
Trijardy XR
empagliflozin + linagliptin + metformin
493
Steglujan
sitagliptin + ertugliflozin
494
Humulin N
insulin NPH intermediate acting
494
Toujeo
insulin glargine long acting
495
Semglee
insulin glargine long acting
496
Lantus
insulin glargine long-acting
496
Novolin N
insulin NPH intermediate acting
497
NovoLog Mix 70/30, 50/50
aspart protamine susp/aspart
497
Humulin 70/30, 50/50
NPH/regular
497
Novolin 70/30
NPH/regular
498
Symlin
pramlintide amylin analog
499
Levemir
insulin detemir long acting
499
Humalog Mix 75/25, 50/50
lispro protamine susp/lispro
500
insulin secretagogues
sulfonylureas [longer-acting] meglitinides [rapid-acting]
500
Victoza
liraglutide GLP-1 agonist
501
Byetta, Bydureon
exenatide GLP-1 agonist
501
peptide analogs
GLP-1 agonists DPP4-i pramlintide
502
insulin sensitizers
glitazones biguanides
503
Tanzeum
albiglutide
504
Juvisync
sitagliptin + simvastatin
504
Trulicity
dulaglutide
504
Cycloset
bromocriptine
504
Neupogen
filgrastim +granulocytes
504
Nyvepria
pegfilgrastim + granulocytes
504
Neulasta
pegfilgrastim + granulocytes
504
Ziextenzo
pegfilgrastim + granulocytes
505
Fulphila
pegfilgrastim + granulocytes
505
Procrit
epoetin + RBC
506
Epogen
epoetin + RBC
507
Retacrit
epoetin + RBC
507
Aranesp
darbepoetin + RBC
507
Neumega
oprelvekin + platelets
507
Leukine
sargramostim + macrophages
507
trx for macrocytic anemia
- vit B12 - folic acid
507
trx for microcyctic anemia
iron
508
trx for normocytic anemia
ESAs
508
Intron A
interferon alpha-2b HCV
509
Mavyret
glecaprevir + pibrentasvir
509
Daklinza
daclatasvir
509
NS3 protease inhibitors for HCV3
- simeprevir - paritaprevir - grazoprevir
509
Harvoni
sofosbuvir + ledipasvir
510
Epclusa
sofosbuvir + velpatasvir
510
Sovaldi
sofosbuvir
511
NS5A inhibitors for HCV
- ledipasvir - ombitasvir - daclatasvir [Daklinza] - elbasvir - velpatasvir [Epclusa, Sofosvel, Velpanat] - glecaprevir
512
Vosevi
sofosbuvir + velpatasvir + voxilaprevir
512
Retrovir
zidovudine NRTI
512
Ziagen
abacavir NRTI
512
Epivir
lamivudine NRTI
512
Exviera
dasabuvir NS5B NNI inhibitor
512
Rubokia
fostemsavir NRTI
513
Combivir
zidovudine + lamivudine NRTI + NRTI
514
Pegasys
PEG-IFN alfa-2a HCV
514
Rebetol
ribavirin
514
Peg-Intron
PEG-IFN alfa-2b HCV
514
Copegus
ribavirin
514
ribavirin clinical pearls
- BBW: hemolyti anemia - preg cat X [2 forms birth control + pregnancy test]
514
Zepatier
grazoprevir + elbasvir NS3 PI
514
Olysio
simeprevir NS3 PI - tk with food - combo with PEGIFN-RBV or sofosbuvir
515
Epzicom
abacavir + lamivudine NRTI + NRTI
516
Trizivir
abacavir + zidovudine + lamivudine NRTI + NRTI + NRTI
516
Cimduo
TDF + lamivudine NRTI + NRTI
516
Viread
TDF - oral powder: tk w/ food NRTI
516
Truvada
TDF + emtricitabine NRTI + NRTI
516
Videx EC
didanosine *on empty stomach NRTI
516
Descovy
TAF + emtricitabine NRTI + NRTI
516
Emtriva
emtricitabine NRTI
517
Tybost
cobicistat PK enhancer
517
Kaletra
ritonavir + lopinavir PI
517
Invirase
saquinavir *take with Norvir [ritonavir] *take w/ food PI
517
Norvir
ritonavir *take w/ food PI booster
517
Prezista
darunavir *sulfa allergy *take w/ food PI
517
Reyataz
atazanavir *take w/ food PI
517
Evotaz
atazanavir + cobicistat
517
Crixivan
indinavir *empty stomach PI
517
Aptivus
tipranavir *sulfa allergy *take w/ food PI
518
Zerit
stavudine NRTI
518
Cabenuva
cabotegravir + rilpivirine INSTI + NNRTI
518
Viracept
nelfinavir *take w/ food PI
518
Lexiva
fosamprenavir *sulfa allergy PI
519
Rescriptor
delavirdine NNRTI
519
Pifeltro
doravirine NNRTI
519
Edurant
rilpivirine *take w/ food NNRTI
520
Intelence
etravirine *take w/ food NNRTI
520
Viramune
nevirapine NNRTI
520
Sustiva
efavirenz *empty stomach NNRTI
521
Fuzeon
enfuvirtide entry inhibitor
522
Tivicay
dolutegravir INSTI
522
Isentress
raltegrevir INSTI
522
Atripla
efavirenz + TDF + emtricitabine *empty stomach NNRTI + NRTI + NRTI
522
Symfi
efavirenz + TDF + lamivudine *empty stomach NNRTI + NRTI + NRTI
522
Selzentry
maraviroc entry inhibitor
522
Vitekta
elvitegravir *take with food *take with other PIs INSTI
522
Complera
rilpivirine + TDF + emtricitabine *take w/ food NNRTI + NRTI + NRTI
523
Stribild
elvitagrevir/cobicistat + TDF + emtricitabine *take w/ food INSTI + NRTI + NRTI
524
Triumeq
dolutegravir + abacavir + lamivudine INSTI + NRTI + NRTI
524
Dovato
dolutegravir + lamivudine INSTI + NRTI
524
Symtuza
darunavir/cobicistat + emtricitabine + TAF *take w/ food PI + NRTI + NRTI
525
Delstrigo
doravirine + lamivudine + TDF NNRTI + NRTI + NRTI
525
Odefsey
emtricitabine + rilpivirine + TAF *take w/ food NRTI + NNRTI + NRTI
526
Genvoya
elvitegravir/cobicistat + emtricitabine + TAF *take w/ food INSTI + NRTI + NRTI
526
Biktarvy
bictegravir + emtricitabine + TAF INSTI + NRTI + NRTI
527
Celexa
citalopram SSRI max 40mg/d bc QT
527
PEP regimen
Truvada QD + raltegravir [Isentress] BID or Tivicay [dolutegravir] QD Truvada QD + darunavir [Prezista] QD and ritonavir [Norvir] QD
527
PrEP regimen
Descovy Truvada
527
Paxlovid
nirmatrelvir/ritonavir
527
Veklury
remsdesivir
527
Lagevrio
molnupiravir
527
antidepressants line of therapy
1st line: SSRI 2nd line: SNRI 3rd line: TCAs, MAOI
528
Lexapro
escitalopram SSRI
529
Zoloft
sertraline SSRI
529
Paxil
paroxetine SSRI
529
Prozac
fluoxetine QAM SSRI
530
Sarafem
fluoxetine *for premenstrual dysphoric disorder
531
Cymbalta
duloxetine DR SNRI
532
Drizalma Sprinkle
duloxetine DR SNRI
533
Effexor
venlafaxine SNRI
534
Trintellix
vortioxetine SNRI
535
Pristiq
desvenlafaxine SNRI
536
Viibryd
vilazodone * with food
537
Wellbutrin
bupropion
538
Zyban
bupropion → for smoking cessation
539
Remeron
mirtazapine
540
Norpramin
desipramine secondary TCA
540
Pamelor
nortripyline secondary TCA
540
Asendin
amoxapine secondary TCA
540
Elavil
amitriptyline tertiary TCA
541
Tofranil
imipramine tertiary TCA
541
Sinequan
doxepin tertiary TCA
541
Silenor
doxepin for insomnia tertiary TCA
541
Anafranil
clomipramine; also for OCD tertiary TCA
542
Marplan
isocarboxazid MAOI
542
Nardil
phenelzine MAOI
542
Parnate
tranylcypromine MAOI
542
Eldepryl
selegiline patch for PD MAOI
542
Emsam
selegiline patch MAOI
542
SJW
MAOI
542
Serzone
nefazodone
542
Desyrel
trazodone
543
Vistaril
hydroxyzine sedating AH
543
anxiety trx
1st line: SSRI, SNRI, TCA alt: hydroxyzine, pregabalin, quetiapine, propranolol
543
LOT BZDs
*safer in elderly lorazepam, oxazepam, temazepam
543
Seroquel
quetiappine
543
Buspar
buspirone 5-HT partial agonist
544
Ambien
zolpidem C-IV BZD receptor agonist
544
Roszerem
ramelteon melatonin receptor agonist
544
Sonata
Zaleplon C-IV BZD receptor agonist
544
Eszopicloneunesta
eszopiclone C-IV BZD receptor agonist
545
Benadryl
diphenhydramine AH
545
Belsomra
suvorexant orexin-receptor antagonist
545
Thorazine
chlorpromazine low potency 1st gen AP
545
Mellaril
thioridazine low potency 1st gen AP
545
Trilafon
perphenazine med potency 1st gen AP
545
Unisom
doxylamine AH
545
Loxitane
loxapine med potency 1st gen AP
545
Moban
molindone med potency 1st gen AP
546
Stelazine
trifluoperazine high potency 1st gen AP
547
Prolixin
fluphenazine high potency 1st gen AP
547
2nd gen AP clinical pearls
- atypical - SE: sedation and metabolic side effects [weight gain, increased BG & TG\ - clozapine BBW: agranulocytosis - clozapine is most effective but reserve for resistant cases; serum >350 ng/mL - ziprasidone has risk of QT prolongation
547
1st gen AP clinical pearls
- typical - SE: EPS, orthostasis, QT prolongation, anticholingeric, skin rxn - DA agonist
547
Haldol
haloperidol high potency 1st gen AP
547
FazaClo ODT
clozapine 2nd gen AP
548
Navane
thiothixene high potency 1st gen AP
548
Zyprexa
olanzapine 2nd gen AP
548
Clozaril
clozapine 2nd gen AP
548
Compazine
prochlorperazine *mainly used as antiemetic high potency 1st gen AP
549
Abilify
aripiprazole 2nd gen AP
549
Geodon
ziprasidone *tk with food 2nd gen AP
549
Seroquel
quetiapine
549
Zydis ODT
olanzapine 2nd gen AP
549
Risperdal
risperidone 2nd gen AP
549
Saphris
asenapine * SL only 2nd gen AP
549
Lybalvi
olanzapine/samidorphan 2nd gen AP
550
which 2nd gen APs are weight neutral
aripiprazole & ziprasidone
551
short-acting 1st gen AP inj
- haloperidol lactate - fluphenazine - chlorpromazine
552
long-acting 1st gen AP
- fluphenazine decanoate - haloperidol decanoate
552
short-acting 2nd gen AP inj
- olanzapine - ziprasidone
552
Aristada
aripiprazole q6wk
552
Perseris
risperidone Q1month
552
long-acting 2nd gen AP inj
- aripiprazole → Maintena [4wk], Aristada [6wk] - olanzapine → Relprevv [2-4wk]; REMS - risperidone → Risperdal Consta [2wk], Perseris [1month] - paliperidone → Sustenna [4wk], Trinza [3 month] - iloperidone
552
Relprevv
olanzapine Q2-4wk
553
Maintena
aripipraole Q4wk
553
Risperdal Consta
risperidone Q2wk
553
Sustenna
paliperidone Q4wk
553
Trinza
paliperidone Q3months
554
Cogentin
benztropine anticholinergic for tremors in PD
554
PD drugs
- anticholinergics - amantadine - MAO-B inhibitors - dopaminergic agents - COMT-i [must use with levodopa] - DA agonists [1st choice]
554
Artane
trihexyphenidyl anticholinergic for initial trx of tremors
554
Eldepryl
selegiline *irreversible MAO-B inhibitor
554
Osmolex ER
amantadine ER decreases DA reuptake for initial trx of tremors & dyskinesias in advanced disease
554
Xadago
safinamide *reversible MAO-B inhibitors can use in renal impairment
554
Symmetrel
amantadine decreases DA reuptake for initial trx of tremors & dyskinesias in advanced disease
554
Azilect
rasagiline *irreversible MAO-B inhibitor
555
Duopa
carbidopa/levodopa enteral susp
555
Rytary
carbidopa/levodopa ER cap
555
Sinemet
carbidopa/levodopa SR tab
555
Ongentys
opicapone COMT inhibitor for off episodes
555
Inbrija
inhaled levodopa
555
Stalevo
carbidopa/levodopa + entacapone
555
Tasmar
tolcapone COMT inhibitor
555
Comtan
entacapone COMT inhibitor
556
Cycloset
bromocriptine *adjunct therapy in diabetes DA agonist
556
Mirapex
pramipexole DA agonist
557
Kynmobi SL
apomorphine SL
557
Requip
ropinirole DA agonist
557
Apokyn SC
apomorphine SC * for advanced disease DA agonist
557
Aricept
donepezil acetylcholinesterase inhibitor
557
Exelon
rivastigmine patch *tk w/food acetylcholinesterase inhibitor
557
Razadyne
galantamine acetylcholinesterase inhibitor
557
Neupro
rotigotine patch DA agonist
557
Alzheimer's trx
- acetylcholinesterase inhibitors - NMDA agonists
558
Namenda
memantine NMDA receptor antagonist
559
Namzaric
mementine ER + donepezil NMDA receptor antagonist + acetylcholinesterase inhibitor
559
Aduhelm
aducanumab monthly IV infusion
559
1st line for atypical absence myoclonic, atonic
- valproate - lamotrigine - levetiracetam
559
1st line for absence seizures
- valproate - ethosuximide
559
Dilantin
phenytoin
559
1st line for partial seizures
- carbamazepine - oxcarbazepine - lamotrigine - levetiracetam
559
1st line for generalized tonic-clonic
- valproate - lamotrigine - levetiracetam
559
Tegretol
carbamazepine
560
Cerebyx
fosphenytoin
561
Trileptal
oxcarbazepine
561
Carbatrol
carbamazepine
561
Topamax
topiramate
561
Epitol
carbamazepine
561
Stavzor
valproate
561
Depakene
valproate
561
Depakote
divalproex
561
Lamictal
lamotrigine
562
Zarontin
ethosuximide
562
Klonopin
clonazepam
563
Keppra
levetiracetam
564
Gabitril
tiagabine
564
Vimpat
lacosamide C-V
564
Neurontin
gabapentin
564
phenytoin clinical pearls
- mix in ND only - max 50mg/min - IV:PO = 1:1 - BBW: teratogenic, skin rash - supplement w/ folic acid, calcium & vit D
564
Sabril
Vigabatrin
564
fosphenytoin clinical pearls
- prodrug of phenytoin - IV:PO= 1:1 - NS/D5W ok - BBW: teratogenic, skin rash
564
Lyrica
pregabalin C-V
564
Barbital
phenobarbital
565
carbamazepine clinical pearls
- therapeutic range: 4-12 mcg/mL - BBW: serious skin rxn, aplastic anemia & agranulocytosis
565
valproate clinical pearls
- therapeutic range: 50-100mcg/mL - BBW: hepatotoxicity, fatal pancreatitis - SE: weight gain
566
topiramate clinical pearls
- CI if sulfa allergy - teratogenic - causes weight loss - oligohydrosis
566
zonisamide clinical pearls
- CI if sulfa allergy - weight loss
566
bipolar depression trx
- quetiapine - quetiapine/fluoxetine - lurasidone
566
levetiracetam clinical pearls
- weight loss *no significant drug interactions
566
Xcopri
cenobamate for partial onset seizures
566
ethosuximide clinical pearls
blood dyscrasias
566
lamotrigine clinical pearls
- max 400mg/day - BBW: skin rash, aseptic meningitis
566
felbamate clinical pearls
- BBW: hepatotoxicity, aplastic anemia
566
bipolar disorder trx
- lithium - anticonvulsants - antipsychotics [off-label]
567
which AP is the only one FDA-approved for bipolar disorder
quetiapine
567
therapeutic range for lithium
0.6-1.2 mEq/L *can still be toxic at therapeutic dose
567
relationship between lithium & salt
decreased salt intake, dehydration = increased lithium increased salt intake, caffeine = decreased lithium
568
Ritalin
methylphenidate
568
therapeutic range of lamotrigine
1-4 ug/mL
568
therapeutic range of valproate
50-125 ug/mL
568
Methylin
methylphenidate
568
Methyl ER
methylphenidate
569
therapeutic range of carbamazepine
4-12 ug/mL
569
ADHD trx
1. stimulants 2. atomoxetine 3. adjunctive trx
569
lithium clinical pearls
- can be toxic at therapeutic dose - ADE: cognitive effects, hand tremor, weight gain, polyuria, polydipsia, hypothyroidism, sedation - DDIs w/ NSAIDs, diuretics, ACE-I/ARB, SSRIs, SNRIs - monitor: BMP, renal, thyroid - drink water & take with meals
569
Aptensio XR
methylphenidate
570
Daytrana
methylphenidate patch
570
Adhansia XR
methylphenidate
570
Jornay PM
methylphenidate
570
Concerta OROS
methylphenidate = TID dosing
570
Azstarys
serdexmethylphenidate/dexmethylphenidate
571
Vyvanse
lisdexamphetamine
571
Focalin
dexmethylphenidate
571
Cotempla XR
methylphenidate ODT
571
Dextrostat
dextroamphetamine
571
Dexedrine
dextroamphetamine
572
Adderall
amphetamine mixed salts
572
Strattera
atomoxetine SNRI - no abuse potential
572
Intuniv
guanfacine ER alpha2 adrenergic agonist
572
Kapvay
clonidine ER alpha2 adrenergic agonist
572
Provigil
modafinil C-IV stimulant for narcolepsy
572
Sunosi
solriamfetol C-IV stimulants for narcolepsy
572
Qelbree
viloxazine for ADHD
572
Nuvigil
armodafinil C-IV stimulant for narcolepsy
573
gout ppx
1. lifestyle modifications 2. anti-inflammatory → colchicine 0.6mg or naproxen 250mg BID, prednisolone/prednisone
574
Uloric
febuxostat decrease UA production
574
gout acute attack trx
- NSAIDs: indomethacin - colchicine - steroids: prednisone, methylprednisolone, triamcinolone
574
Benemid
probenecid increase UA excretion
574
Aloprim
allopurinol IV decrease UA production
574
gout management trx
decrease UA production: - allopurinol w/ meal - febuxostat increase UA excretion - probenecid [Benemid] - other agents: losartan, fenofibrate
574
AlternaGel
aluminum hydroxide aluminum-based phosphate binder
574
Zyloprim
allopurinol PO decrease UA production
574
Phoslyra
calcium acetate calcium based phosphate binder
574
Amphojel
aluminum hydroxide aluminum based phosphate binder
574
PhosLo
calcium acetate calcium based phosphate binder
575
TUMS
calcium carbonate calcium based phosphate binder
575
Fosrenol
lanthanum carbonate Al/Ca-free phosphate binder
575
Renvela
sevelamer Al/Ca-free phosphate binder
576
Drisdol
ergocalciferol Vit D2 inactive vit D
576
Antivert
meclizine AH
576
Compazine
prochlorperazine
576
Rocatrol
calcitriol Vit D3 active vit D
576
Renagel
sevelamer Al/Ca-free phosphate binder
576
N/V trx for pregnancy
1st line: - vit B6 [pyridoxine] - AH: doxylamine [Unisom], diphenhydramine, meclizine [Antivert, Dramamine] 2nd line: - DA antagonist: promethazine [Phenergan], prochlorperazine [Compazine], metoclopramide [Reglan] 3rd line: - 5HT antagonist: ondansetron [Zofran] - corticosteroids [avoid 1st trimester]: methylprednisolone, dexamethasone, prednisolone
576
Unisom
doxylamine AH
577
Phenergan
promethazine
577
Dramamine
meclizine AH
577
Reglan
metoclopramide
577
motion sickness trx
scopolamine 3-day patch
577
Zofran
ondansetron
578
Transderm Scop
scopolamine 3-day patch
579
nicotine lozenge dosing
4mg if smoke 30 min of awakening 2mg if smoking 30 min or later of awakening - use at least 9 pieces/day for first 6 weeks - 3 month regimen
579
nicotine gum dosing
2mg if <25 cigs/day 4mg if >25 cigs/day - at least 9 pieces/day for first 6 weeks - 3 month regimen
579
nicotine nasal spray dosing
1-2 doses per hour for 3 months 1 dose = 2 sprays = 1 spray in each nostril = 1mg nicotine - max 5 doses/hr or 40 doses/day
579
nicotine patch dosing
1. 21mg/day 2. 14mg/day 3. 7mg/day - duration 8-10 weeks - wear for 16 hours
579
nicotine inhaler dosing
continuous puffing for 20 min max 16 cartridges/day
579
bupropion dosing for smoking cessation
SR 150mg QD x3 days → 150mg BID x7-12 weeks - stop smoking after 1-2 weeks of treatment
579
oral agents for smoking cessation
- bupropion SR [Zyban 150 SR} - varenicline [Chantix]
580
varenicline dosing for smoking cessation
0.5mg QD → 0.5mg BID → 1mg BID - start 1 week before quit day
580
Chantix
varenicline
581
Zomig
zolmitriptan 5HT1 agonist
581
Reyvow
lasmiditan serotonin 1F agonist for acute trx of migraine
581
Fioricet
APAP + butalbital + caffeine for migraines
581
Maxalt
rizatriptan 5HT1 agonist
581
Fiorinal
ASA + butalbital + caffeine C-III for migraine trx
582
Migranal
dihydroergotamine ergot alkaloids preg cat X
582
Relpax
eletriptan 5HT1 agonist
582
Imitrex
sumatriptan 5HT1 agonist
582
migraine ppx
- topiramate - propranolol - timolol - amitriptyline - divalproex
583
Nurtec ODT
remegepant calcitonin gene-related peptide receptor antagonist for acute trx of migraine
583
FROVA
frovatriptan succinate for acute trx of migraines
583
Ajovy
fremanezumab for migraine ppx
583
Aimovig
erenumab for migraine ppx
583
estrogen CI
- breast cancer - DVT/PE/stroke/MI - liver dysfunction - pregnancy
583
Qulipta
atogepant calcitonin gene-related peptide receptor antagonist for migraine prevention
583
Emgality
galcanezumab for migraine ppx
584
Vyepti
eptinezumab for migraine ppx
585
progestin HRT
- medroxyprogesterone [Provera PO & Depo-Provera IM/SC] - HRT/amenorrhea/endometriosis: lower dose - contraception: 150mg IM or 104mg SC Q3months - POP/mini-pill for birth control - MIRENA: IUD
585
estrogen HRT
*only for women w/ no uterus* tab: Estrace, Premarin, Cenestin patch: Alora, Climara, Estraderm/Vivelle Dot vag ring: Estring, Femring top: Estrasorb
585
testosterone formulations
oral: Androxy, Android, Methitest, Testred, Jatenzo IM: Depo-Testosterone, Delatestryl, Xyosted, Aveed top gel: AndroGel 1%, AndroGel 1.62%, Fortesta 2%, Testim 1% top sol: Axiron 2% nasal gel: Natesto buccal tabs: Striant SC pellets: Testopel transdermal: Androderm 24H
586
Delatestryl
testosterone enanthate IM
586
Xyosted
testosterone enanthate SC
586
monophasic COC
YASMIN Apri Femcon Fe Loestrin Low-Ogestrel Desogen Demulen Ortho-Cyclen Ovcon Ortho-Novum Necon
587
estrogen + progestin HRT
*women with a uterus* tab: Activella, Femhrt, Estratest [w/ testosterone] and Premphase or Prempro [w/ medroxyprogesterone] patch: Climara Pro, CombiPatch
587
Aveed
long-acting undecanoate REMS
587
Depo-Testosterone
testosterone cypionate
588
four-phasic COC
NATAZIA for heavy menstrual bleeding
588
which COCs have drospirenone
Yasmin, Nextstellis, Yaz, Beyaz
588
bi-phasic COC
Kariva Mircette Ortho-Novum 10/11
588
tri-phasic
Ortho Tri-Cyclen Cyclessa EstroStep Triphasil Tri-Norinyl Ortho-Novum 7/7/7
589
extended-cycle COC
- 24 days: Nextstellis, YAZ, Beyaz - 3 months: Seasonale & Seasonique - 12 months: Amethyst
589
Nextstellis
drospirenone/estetrol
589
combined hormonal patches
Xulane Twirla
589
combined hormonal vaginal ring
NuvaRIng Qmonth Annovera reuse up to 1 year
589
norethindrone POPs
Ortho Micronor Camila Errin Jencycla Nor-QD
590
drospirenone POP
Slynd
591
progestin only IUD
levonorgestrel → Mirena, Skyla
591
Plan B Next Choice
two 0.75mg tabs of levonorgestrel Q12H
591
Ella
ulipristal
591
progestin only implant
etonogestrel
591
which drugs do you need back up contraception for
- rifampin - ABXs - AEDs - SJW - antiretrovirals
591
Plan B One-Step
one 1.5mg tab of levonorgestrel
591
progestin only shot
medroxyprogesterone acetate
592
hypothyroidism description
- low T4 - Hashimoto's, Cretinism, Myxedema - fatigue, weight gain, cold intolerance, hoarseness, dry skin, constipation, puffy face, muscle weakness - due to lithium, amiodarone, interferons
592
hyperthyroidism descriptoin
- high T4 - Graves', Plummer's , thyrotoxicosis - heat intolerance, exopthalmos, sweating, weight loss, irritability, insomnia, tachycardia - due to iodide, amiodarone, interferons
593
levothyroxine IV:PO
IV:PO = 0.75:1
593
Cytomel, Triostate
liothyronine; T3 thyroid supplement
593
Tapazole
methimazole DOC thionamide
593
levothyroxine colors
Orangutans Will Vomit On You Right Before They Become Large, Proud Giants 25 mcg - orange 50 mcg - white [no dye] 75 mcg - violet 88 mcg - olive 100 mcg - yellow 112 mcg - rose 125 mcg - brown 137 mcg - turquoise 150 mcg - blue 175 mcg - lilac 200 mcg - pink 300 mcg - green
593
Armour Thyroid
thyroid desiccated; T4 + T3 thyroid supplement
593
Thyrolar
Liotrix; T4 + T3 thyroid supplement
593
Levothroid, Levoxyl, Synthroid, Unithroid
levothyroxine; T4 thyroid supplement
594
PTU
propylthiouracil thionamide
595
hyperthyroid in pregnancy
1st trimester: PTU 2nd & 3rd: methimazole
596
Zonegran
zonisamide
596
Luminal
phenobarbital
597
Mysoline
primidone
598
SSKI, Lugol's solution
iodide for thyroid storm
599
Citracal
calcium citrate
600
osteoporosis trx
- bisphosphonates - denosumab - raloxifene - estrogen-progestin replacement therapy - calcitonin - teriparatide
601
Boniva
ibandronate Q3 mo bisphosphonate PO or IV
602
Reclast
zoledronic acid Qyear bisphosphonate
603
Actonel
risendronate bisphosphonate
604
Atelvia
risedronate DR bisphosphonate
605
Fosamax
alendronate bisphosphonate
606
Prolia
denosumab for osteoporosis
606
Xgeva
denosumab for malignancy
606
Evista
raloxifene estrogen rec. modulator
606
Miacalcin
calcitonin inj
606
Fortical
calcitonin nasal
606
Forteo
teriparatide parathyroid hormone analog
606
Taxotene
docetaxel taxane M phase antimicrotubule
606
Taxol, Onxol, Paxene
paclitaxel taxane M phase antimicrotubule
607
Navelbine
vinorelbine vinca alkaloid M phase specific antimicrotubule
607
Velban, Velbe
vinblastine vinca alkaloid M phase specific antimicrotubule
607
Vincasar, Oncovin, Vincrex
vincristine vinca alkaloid M phase specific antimicrotubule
607
chemo antimicrotubule agents
epothilones halicondrin B analogues taxanes vinca alkaloids
608
M topo II inhibitors
anthracemedione anthracyclines epipodophyllotoxins
609
Cerubidine
daunorubicin anthracycline M topo II inhibitor
609
Adriamycin, Doxil, Rubex, Caelyx, Myocet
doxorubicin anthracycline M topo II inhibitor
609
Ellence
epirubicin anthracycline M topo II inhibitor
609
Idamycin
idarubicin anthracycline tM opo II inhibitor
609
Novantrone
mitoxantrone anthracycline M topo II inhibitor
609
Zinecard
dexrazoxane prevents heart damage from anthracyclines
609
Totect
dexrazoxane treats extravasation
610
Paraplatin
carboplatin platinum-based compound
610
Platinol
cisplatin platinum-based compound
610
Eloxatin
oxaliplatin platinum-based compound
610
S topo II inhibitors
anthracemedione anthracyclines
610
Camptosar
irinotecan S topo II inhibitor S phase specific
611
VePesid, Etopophos, Toposar
etoposide S topo II inhibitor S phase specific
612
Hycamtin
topotecan S topo II inhibitor S phase specific
612
antimetabolites
folate antagonists purine analogues pyrimidine analogues hydroxyurea
612
Imuran
azathioprine purine analog metabolite S phase specific
612
Fludara
fludarabine purine analog metabolite S phase specific
612
Purinethol
6-mercaptopurine purine analog metabolite S phase specific
612
Lanvis, Tabloid
6-thioguanine purine analog metabolite S phase specific
612
Alimta
pemetrexed folate metabolite S phase specificolate
612
Rheumatrex, Trexall, Mexate
methotrexate folate metabolite S phase specificolate
612
methotrexate antidotes
leucovorin [folic acid]
612
Xeloda
capecitabine [5-FU prodrug] pyrimidine analog s phase specific
612
Adrucil, Carac, Efudex
5-FU pyrimidine analog s phase specific
613
Cytosar-U
cytarabine pyrimidine analog s phase specific
613
Gemzar
gemcitabine pyrimidine analog s phase specific
613
Treanda
bendamustine alkylator
614
Busulfex inj, Myleran
busulfan alkylator
614
Thioplex
thiotepa alkylator
614
BiCNU, Gliadel
carmustine alkylator
614
Leukeran
chlorambucil alkylator
614
Cytoxan, Neosar, Procytox
cyclophosphamide alkylator
614
Ifex
ifosfamide alkylator
614
CeeNU
lomustine alkylator
614
Zytiga
abiraterone prostate cancer
614
Casodex
bicalutamide prostate cancer
614
Zoladex
goserelin prostate cancer
614
Eulexin
flutamide prostate cancer
614
Lupron
leuprolide prostate cancer
615
Gleevec, Glivec
imatinib TKI
615
Tarceva
erlotinib TKI
615
Afinitor
everolimus TKI
615
Sprycel
dasatinib TKI
616
Tasigna
nilotinib TKI
616
Sutent
sunitinib TKI
616
Nexavar
sorafenib TKI
617
Iressa
gefitinib TKI
617
Tykerb
lapatinib TKI
617
Aliqopa
copanlisib TKI
618
Alunbrig
brigatinib TKI
618
Calquenbce
acalabrutinib TKI
618
Kisqali
ribociclib TKI
618
Nerlynx
neratinib TKI
618
Rydapt
midostaurin TKI
618
Verzenio
abemaciclib TKI
618
Revimid
lenalidomide immunomodulator
618
Proleukin
aldesleukin, IL-2 immunomodulator
618
Aldara
imiquimod immunomodulator
618
Thalomid
thalidomide immunomodulator REMS
618
Rituxan
rituximab mAb
618
Avastin
bevacizumab mAb
618
Herceptin
trastuzumab mAb
618
Erbitux
cetuximab mAb
619
Yervoy
ipilimumab mAb
620
Campath
alemtuzumab mAb
620
Mylotarg
gemtuzumab mAb
620
Zevalin
irbritumomab mAb
620
Bexxar
tositumomab mAb
621
Velcade
bortezomib
621
Elspar
asparaginase
621
Blenoxane
bleomycin
621
Cosmegen
dactinomycin
621
Targretin
bexarotene
621
Alkeran
melphalan
622
Emcyt
estramustine
622
Hydrea
hydroxyurea
622
Mutamycin
mitomycin
622
Mustargen
mechlorethamine
623
Zanosar
streptozocin
623
Idhifa
enasidenib
623
Zejula
niraparib
623
Arimidex
anazstrole oral aromatase inhibitors [after menopause] for breast cancer
623
Aromasin
exemestane oral aromatase inhibitors [after menopause] for breast cancer
624
Femara
letrozole oral aromatase inhibitors [after menopause] for breast cancer
624
Faslodex
fulvestrant oral aromatase inhibitors [after menopause] for breast cancer
625
Fareston
toremifene oral estrogen blocker for breast cancer
625
Nolvadex
tamoxifen oral estrogen blocker for breast cancer
625
Megace
megestrol for breast & uterine cancer
625
Metamucil
psyllium fiber/bulk forming laxative
625
Citrucel
methylcellulose fiber/bulk forming laxative
625
FiberCon
polycarbophil fiber/bulk forming laxative
625
Colace
docusate sodium stool softener [emolient]
625
Kaopectate Liqui-Gel
docusate calcium stol softener [emollient]
625
Nujol
mineral oil lubricant
625
Dulcolax
bisacodyl stimulant
625
Senokot, Ex-lax
senna stimulant
625
Citroma
magnesium citrate saline cathartic osmotic laxative
626
Epsom salt
magnesium sulfate saline cathartic osmotic laxative
626
Milk of Magnesia
magnesium hydroxide saline cathartic osmotic laxative
626
Fleets Phospho-Soda
sodium phosphate saline cathartic osmotic laxative
626
Duphalac, Chronulac
lactulose hyperosmotic osmotic laxative
626
Miralax, Carbowax, Golytely
polyethylene glycol hyperosmotic osmotic laxative
626
Relistor
methylnaltrexone gut opioid blocker only for pts on opioids & failed docusate + senna or bisacodyl
626
Trulance
plecanatide chronic idiopathic constipation
626
Linzess
linaclotide chronic idiopathic constipation
627
Amitiza
lubiprostone chronic idiopathic constipation
627
Imodium
loperamide diarrhea
627
Lomotil
diphenoxylate + atropine C-V diarrhea
628
Pepto-Bismol, Kaopectate
bismuth subsalicylate
628
Lotronex
alosetron for women w/ IBD + diarrhea as main symptom
628
Bentyl
dicyclomine antispasmodic [anticholinergic]
628
Azulfidine, Sulfazine
sulfasalazine aminosalicylate
628
Asacol, Pentasa, Lialda, Canada supp, Rowasa enema
mesalamine aminosalicylate for IBD
628
IBD maintenance
1. aminosalicylates - sulfasalazine - mesalamine 2. immunosuppressives - azathioprine - 6-mercaptopurine - methotrexate 3. mAbs - infliximab - adalimumab - certolizumab - natalizumab
628
Remicade
infliximab
628
Humira, Cyltezo, Abrildad, Hadlima
adalimumab
629
Cimzia
certolizumab
629
Tysabri
natalizumab
629
Avonex
interferon beta-1a 1x weekly SC immune modulator for MS
629
Rebif
interferon beta-1a 3x/weekly SC immune modulator for MS
629
Betaseron
interferon beta-1b QOD SC immune modulator for MS
629
Extavia
interferon beta-1b QOD SC immune modulator for MS
630
Copaxone
glatiramer acetate SC immune modulator for MS
630
Plegridy
peginterferon beta-1a SC immune modulator for MS
630
Kesimpta
ofatumumab SC immune modulator for MS
630
GIlenya
fingolimod oral immune modulator for MS
630
Aubagio
teriflunomide SC immune modulator for MS
631
Tecfidera
dimethyl fumarate SC immune modulator for MS
631
Mayzent
siponimod SC immune modulator for MS
631
Vumerity
diroximel fumarate SC immune modulator for MS
631
Zeposia
ozsanimod SC immune modulator for MS
631
Ponvory
ponesimod SC immune modulator for MS
632
Tysabri
natalizumab mAb for MS
632
Lemtrada
alentuzumab mAb for MS
632
Ocrevus
ocrelizumab mAb for MS
632
Rituxan
rituximab mAb for MS
633
Ampyra
dalfampridine to help improve walking in MS
634
Pepcid
famotidine H2RA
634
Axid
nizatidine H2RA
634
Tagamet
cimetidine H2RA
634
Prilosec
omeprazole PPI
634
Zegerid
omeprazole/Na bicarb PPI
634
Nexium
esomeprazole PO or IV PPI
634
Prevacid
lansoprazole PPI
635
Dexilant
dexlansoprazole PPI
635
Aciphex
rabeprazole
635
Protonix
pantoprazole PO or IV PPI
635
Reglan
metoclopramide
635
Carafate
sucralfate cytoprotective agent
635
Cytotec
misoprostol cytoprotective agent
635
Pepto-Bismol
bismuth subsalicylate cytoprotective agent antidiarrheal
636
triple therapy LAC regimen
lansoprazole amoxicillin BID clarithromycin BID x10-14 day
637
triple therapy BMT
bismuth metronidazole tetracycline x14 days
637
triple therapy PrevPac
lansoprazole amoxicllin clarithromycin BID x14 days
637
quadruple therapy Pylera
bismuth metronidazole tetracycline QID PPI BID x10 days
637
quadruple therapy Helidac
bismuth metronidazole tetracycline QID x14 days H2RA x28 days
637
NSAID BBW
COX-2 selective: CV thrombotic events COX-1 selective: GI bleeding
637
Bayer, Ascriptin, Bufferin, Ecotrin
aspirin cardioprotection
637
Aleve
naproxen OTC 220mg BID
638
Naprosyn, Naprelan, Anaprox
naproxen Rx
638
Vimovo
naproxen + esomeprazole
638
Indocin
indomethacin for gout
638
Feldene
piroxicam most GI toxic
638
Toradol
ketorolac most GI toxic 5 days max trx
638
Ultracet
APAP + tramadol
639
antidote for APAP
NAC
640
Motrin, Advil
ibuprofen
641
Cataflam, Voltaren
diclofenac
642
Celebrex
celecoxib COX-2 selective
643
Arthrotec
diclofenac + misoprostol
644
Mobic
meloxicam COX-2 selective
645
Lodine
etodolac COX-2 selective
646
Dolobid
diflunisal COX-2 selective
647
Ofirmev
IV APAP
648
Caldolor
IV ibuprofen
649
Clinoril
sulindac
650
Daypro
oxaprozin
651
Disalcid
salsalate
652
Orudis
ketoprofen
653
Embeda
morphine + naltrexone
654
Vantrela ER
hydrocodone abuse deterrent
655
Narcan
naloxone
656
Suboxone
buprenorphine + naloxone
657
Subutex
buprenorphine SL
657
Cassipa
buprenorphine + naloxone higher strength
658
Sublocade
buprenorphine SC Qmon
659
Buprenex, Butrans, Probuphine, Belbuca
buprenorphine implant
660
Stadol
butorphanol C-IV opioid agonist
660
Nubain
nalbuphine opioid agonist
660
Talwin
pentazocine C-IV opioid agonist
660
Robaxin
methocarbamol muscle relaxant
660
Zanaflex
tizanidine muscle relaxant
660
Lucemyra
lofexidine opioid agonist
660
Soma
carisoprodol C-IV muscle relaxant
660
Savella
milnacipran for fibromyalgia
660
Proventil HFA
albuterol MDI SABA
661
Lioresal
baclofen muscle relaxant
661
Flexeril
cyclobenzaprine muscle relaxant
661
Skelaxin
metaxalone muscle relaxant
662
ProAri HFA
albuterol MDI SABA
662
Volmax
albuterol sol SABA
662
Maxair Autohaler
pirbuterol MDI SABA
662
Alvesco
Ciclesonide ICS
662
QVAR
beclomethasone ICS
662
AccuNeb
albuterol nebulized SABA
663
Xopenex HFA
levalbuterol MDI SABA
663
Azmacort
triamcinolone ICS
663
Flovent
fluticasone ICS
663
Asmanex
mometasone ICS
664
Ventolin HFA
albuterol MDI SABA
664
Proventil
albuterol tabs SABA
664
asthma initial therapy
1. ICS +/- LTRA 2. ICS/LABA 3. ICS/LABA + LAMA advanced therapy: anti-IgE or anti-IL-5
664
Aerospan, Aerobid
Flunisolide ICS
664
Advair
fluticasone + salmeterol ICS + LABA
665
24 hour acting LAMAs
tiotropium glycopyrronium umeclidinium
665
Dulera
mometasone + formoterol ICS + LABA
665
Serevent Diskus
salmeterol 12 hour LABA
665
Symbicort
budesonide + formoterol ICS + LABA
665
12 hour acting LAMAs
aclidinium darotropium
665
Foradil Aerolizer
formoterol 12 hour LABA
665
Accolate
zafirlukast LTRA
665
Intal
cromolyn sodium mast cell stabilizer
665
Singulair
montelukast LTRA
665
Zyflo CR
zileuton LTRA
666
Pulmicort
budesonide ICS
666
24 hour duration LABAs
indacaterol vilanterol olodaterol abediterol carmoterol
666
Elixophyllin, Theo-24, TheoCap, Uniphyl, Theochron
theophylline bronchodilator
667
Xolair
omalizumab anti-IgE
667
Fasenra
benralizumab anti IL-5 for eosinophilic disease
667
Nucala
mepolizumab anti IL-5
667
Cinqair
reslizumab anti IL-5
667
Flonase, Veramyst
fluticasone nasal
667
MDI instructions
1. prime 2. shake well [except QVAR & Alvesco] 3. use spacer or rinse mouth 4. slowly breath out, hold & breathe normally 5. clean weekly
667
DPI instructions
1. no priming 2. don't shake 3. use mouthpiece [no spacers] 4. inhaled dose fast & deep 5. don't inhale into device 6. rinse mouth 7. don't clean, keep dry
668
Rhinocort Aqua
budesonide nasal
668
Nasarel
flunisolide nasal
668
Beconase AQ
beclomethasone nasal
668
Omnaris
ciclesonide nasal
668
NasalCrom
cromolyn sodium nasal
668
Nasonex
mometasone nasal
668
COPD initial therapy
1. LAMA or LABA 2. LAMA/LABA 3. LAMA/LABA + ICS advanced therapy - chronic macrolides - roflumilast
669
Lonhala
glycopyrrolate inhalation sol
669
Hytrin
terazosin alpha-1 blocker BPH
669
Avodart
dutasteride 5-alpha reductase inhibitor for BPH
669
Cardura
doxazosin alpha-1 blocker BPH
669
Flomax
tamsulosin alpha-1 blocker BPH
669
Uroxatral
alfuzosin alpha-1 blocker BPH
669
Daliresp
roflumilast PDE 4 inhibitor
669
Proscar
finasteride 5-alpha reductase inhibitor for BPH
669
Minioress
prazosin alpha-1 blocker BPH
669
Rapaflo
silodosin alpha-1 blocker BPH
669
Propecia
finasteride for male pattern baldness
669
Levitra
vardenafil PDE-5 inhibitor for ED
670
Revatio
sildenafil PDE-5 inhibitor for PAH
670
Viagra
sildenafil PDE-5 inhibitor for ED
670
Adcirca
tadalafil PDE-5 inhibitor for PAH
670
Caverject
alprostadil inj for ED
670
Tracleer
bosentan PAH
670
Detrol
tolterodine anticholinergic for urinary incontinence/overactive bladder
670
Vesicare
solifenacin anticholinergic for urinary incontinence/overactive bladder
670
Prostacyclin, Flolan
epoprostenol PAH
670
Staxyn ODT
vardenafil ODT PDE-5 inhibitor for ED
670
Cialis
tadalafil PDE-5 inhibitor for ED & BPH
670
Ventavis
Iloprost PAH
671
Ditropan, Oxytrol
oxybutynin anticholinergic for urinary incontinence/overactive bladder
671
Enablex
darifenacin anticholinergic for urinary incontinence/overactive bladder
672
Myrbetriq
mirabegron anticholinergic for urinary incontinence/overactive bladder
672
Tavist
clemastine 1st AH
672
Toviaz
fesoterodine anticholinergic for urinary incontinence/overactive bladder
672
Sanctura
trospium anticholinergic for urinary incontinence/overactive bladder
672
Chlor-Trimeton
chlorpheniramine 1st AH
672
Unisom
doxylamine 1st AH
672
Benadryl
diphenhydramine 1st AH
672
Zyrtec
cetirizine 2nd gen AH
672
Phenergan
promethazine 1st AH
672
Claritin
loratadine 2nd gen AH
672
Allegra
fexofenadine 2nd gen AH
672
Xyzal
levocetirizine 2nd gen AH
673
Clarinex
desloratadine 2nd gen AH
673
Coricidin HBP
chlorpheniramine + dextromethorphan + guaifenesin + APAP alpha-adrenergic agonist
673
Privine
naphazoline decongestant nasal
673
Astelin, Astepro
azelastine 2nd gen AH nasal
673
Patanase
olopatadine 2nd gen AH nasal
673
Sudafed
pseudoephedrine decongestant
673
Otrivin
xylometazoline decongestant nasal
673
Neo-Synephrine 4-hour
phenylephrine decongestant nasal
673
Delsym
dextromethorphan antitussive
673
Sudafed PE
phenylephrine decongestant
673
Afrin, Neo-Synephrine 12-Hr
oxymetazoline decongestant nasal
673
Travatan 2
travoprost prostaglandin analog glaucoma
673
Mucinex
guaifenesin expectorant
674
Xelpros
latanoprost w/o preservative prostaglandin analog glaucoma
674
Lumigan, Durysta Implant
bimatoprost prostaglandin analog glaucoma
674
Betoptic S
betaxolol beta-blocker glaucoma
674
Timoptic
timolol beta-blocker glaucoma
674
Zioptan
tafluprost prostaglandin analog glaucoma
674
Betagan
levobunolol beta-blocker glaucoma
674
Trusopt
dorzolamide carbonic anhydrase inhibitor glaucoma
674
Xalatan
latanoprost w/ preservative prostaglandin analog glaucoma
674
Vyzulta
latanoprostene bunod prostaglandin analog glaucoma
674
Ocupress
carteolol beta-blocker glaucoma
674
Cosopt
dorzolamide/timolol carbonic anhydrase inhibitor glaucoma
674
OptiPranolol
metipranolol beta-blocker glaucoma
675
Azopt
brinzolamide carbonic anhydrase inhibitor glaucoma
676
Diamox
acetazolamide diuretic glaucoma
676
Alphagan 0.1%, 0.15%, 0.2%
brimonidine alpha-agonist/adrenergic glaucoma
676
Combigan
brimonidine/timolol alpha agonist/adrenergic
676
Emadine
emedastine AH allergic conjunctivitis
676
Lumify 0.025%
brimonidine alpha-agonist/adrenergic OTC low-dose ocular redness
676
Rhopressa
netarsudil rho kinase inhibitor glaucoma
676
Zaditor, Alaway
ketotifen AH allergic conjunctivitis
676
Naphcon-A, Opcon-A, Visine-A
naphazoline/pheniramine AH/decongestant allergic conjunctivitis
676
Alocril
nedocromil mast cell stabilizer allergic conjunctivitis
676
Acular
ketorolac NSAID allergic conjunctivitis
676
Lotemax
loteprednol allergic conjunctivitis
676
Restasis
cyclosporine 0.05% ophth dry eyes
676
Optivar
azelastine AH allergic conjunctivitis
677
Azasite
azithromycin bacterial conjunctivitis
677
Vigamox
moxifloxacin bacterial conjunctivitis
677
Ciloxan
ciprofloxacin bacterial conjunctivitis
677
Tobrex
tobramycin bacterial conjunctivitis
677
Garamycin
gentamicin bacterial conjunctivitis
677
Polytrim
trimethoprim/polymyxin bacterial conjunctivitis
677
Neosporin
neomycin/bacitracin/polymyxin bacterial conjunctivitis
678
Besivance
besifloxacin bacterial conjunctivitis
678
Cequa
cyclosporine 0.09% ophth dry eyes
678
Ocuflox
ofloxacin bacterial conjunctivitis
678
A/B Otic, Auralgan
antipyrine/benzocaine otitis media
678
Americaine Otic
benzocaine otitis media
679
Cerumenex
triethanolamine ear wax removal
679
Topicort
desocimetasone 0.05-0.25% high potency top steroid
679
Floxin Otic
ciprofloxacin otitis media
679
Cipro HC
ciprofloxacin/hydrocortisone otitis media
679
Debrox
carbamide peroxide ear way removal
679
Vanos cream, Lidex
fluocinonide 0.05-0.1% high potency top steroid
679
Ciprodex
ciprofloxacin/dexamethasone otitis media
679
Ultravate
halobetasol 0.05% high potency top steroid
679
Cortisporin
neomycin/hydrocortisone otitis media
679
Kenalog
triamcinolone 0.1% med potency top steroid
679
Clobex, Cormax, Olux, Temovate
clobetasol 0.05% high potency top steroid
680
Psorcon
diflorasone 0.05% high potency top steroid
680
Elocon
mometasone 0.1% med potency top steroid
681
Benoxyl, Benzac, Clearsil, BenzaClin, Duac
topical benozyl peroxide acne
681
DermAtop
prednicarbate 0.1% med potency top steroid
681
Differin
adapalene top retinoid acne
681
Tazorac
tazarotene top retinoid acne
681
Hytone
hydrocortisone 0.5-2.5% low potency top steroid
681
Retin-A, Avita
tretinoin top retinoid acne
681
Cultivate
fluticasone 0.005% med potency top steroid
681
Aczone
dapsone gel top retinoid acne
681
DesOwen
desonide 0.05% low potency top steroid
681
Lamisil
terbinafine 1%
681
Nizoral A-D
ketoconazole
681
Accutane, Claravis, Absorica, Amnesteem, Sotret
PO isotretinoin acne
681
Lotrimin
clotrimazole 1%
682
Nizoral
ketoconazole cream
682
Diflucan
fluconazole
682
Sporanox
itraconazole onychomycosis
682
Eucrisa
crisaborole atopic dermatitis
682
Elidel
pimecrolimus atopic dermatitis
682
Elimite
permethrin 5% Rx lice
682
Natroba
spinosad lice
682
RID
pyrethrin lice
683
Protopic
tacrolimus atopic dermatitis
683
Penlac
ciclopirox
683
NIX
permethrin 1% OTC lice
683
Xeglyze
Abametapir lice
683
Dupixent
dupilumab atopic dermatitis
684
Aldara
imiquimod genital warts
684
Abreva
docosanol HSV1 cold sores
684
Ivy Block
bentoquatam poison ivy
684
Bactroban
mupirocin
684
Dovonex
calcipotriene psoriasis
684
Neosporin
polymyxin + bacitracin + neomycin
684
Aveeno
colloidal oatmeal poison ivy
684
Taclonex
calcipotriene + betamethasone psoriasis
684
Polysporin
bacitracin + polymyxin
684
Caladryl
calamine poison ivy
684
Burrows
Zanfel, aluminum sol poison ivy
685
Tazorac
tazarotene psoriasis
685
Anthranol, Psoriatec
anthralin psoriasis
686
Atrovent
ipratropium LAMA
686
Spiriva
tiotropium LAMA
686
Combivent
ipratropium + albuterol LAMA + SABA
686
Breztri Aerosphere
budesonide + glycopyrrolate + formoterol corticosteroid + anticholinergic + LABA
686
Stiolto Respimat
tiotropium/olodaterol LAMA/LABA
687
Tudorza
aclidinium LAMA
687
Duaklir Pressair
aclidinium/formoterol LAMA/LABA
687
Brovana
arformoterol 12 hour LABA for COPD
687
Arcapta
indacaterol LABA
687
Breo Ellipta
fluticasone + vilanterol ICS + LABA
687
Anoro Ellpita
umeclidinium + vilanterol anticholinergic + LABA
687
Trelegy Ellipta
umeclidinium + fluticasone + vilanterol LAMA + ICS + LABA
687
Seebri Neohaler
glycopyrrolate DPI
688
Neoral, Sandimmune
cyclosporie psoriasis
688
Soriatane
acitretin psoriasis
688
Xofluza
baloxavir influenza
688
Rogaine
minoxidil
688
influenza vaccines w/o eggs
flublock
688
FluMist, MedImmune
influenza nasal vaccine
688
what is calcium chloride incompatible with
- mag sulfate - propofol - sodium bicarbonate
688
which drugs must be protected from light
- ampB → D5W - linezolid - NTG - NE → D5W or NS - nitroprusside
688
Tamiflu
oseltamivir x5 day influenza
688
Rapivab
peramivir x1 influenza
688
what is sodium bicarb incompatible with
- amiodarone - calcium chloride - dobutamine - epi/NE - isoproterenol
688
Relenza
zanamivir x5 days oral inh influenza
688
which drugs to dilute in NS
- fluconazole - daptomycin - flagyl → don't refrigerate - amp, unasyn - ertapenem - primaxin - erythromycin - insulin
688
short stability drugs
- bactrim → D5W, don't refrigerate, 4-6 hours - phenytoin → NS, don't refrigerate, 2 hours - levothyroxine → NS, mix on floor - infliximab → NS, 3 hours - filgrastim → NS, 6 hours
688
which drugs to dilute in D5W
- amiodarone - synercid - cipro
689
patches 12 on 12 off
NTG lidocaine → can cut
690
twice a week patches
- alora, estraderm, vivelle dot - oxybutynine
690
sulfa drugs
- sulfa ABX - dapsone - HIV PI: darunavir, fosamprenavir, tipranavir - HCV PI: simeprevir generally tolerated: - loop & thiazide diuretics - SUs - carbonic anhydrase inhibitors - HIV & HCV Pis - celecoxib, diazoxide, ibutilide, probenecid, sotalol, sumatriptan, tipranavir, topiramate, zonisamide
690
daily patches
selegiline [Emsam] methylphenidate [Daytrana] rivastigmine [Exelon] testosterone [Androderm] nicotine patch [NicoDerm, Habitrol]
690
Q72H patches
- fentanyl - scopolamine
690
weekly patches
- climara, menostar [HRT] - clonidine - buprenorphine - anticonceptive patch

CPJE (3 decks)

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