CPTP 3.12 - Choosing the Right Antibiotic Flashcards Preview

Clinical Pharmacology Therapeutics and Prescribing > CPTP 3.12 - Choosing the Right Antibiotic > Flashcards

Flashcards in CPTP 3.12 - Choosing the Right Antibiotic Deck (12)
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1
Q

Name the three major bacteria causing meningitis in infants?

A

Group.B streptococcus
Listeria monocytogenes
E.coli

2
Q

Name the three major bacteria causing meningitis in childhood?

A

Haemophilus influenza
Neisseria meningitidis
Strep pnuemoniae

3
Q

Name the major bacteria causing meningitis is adults?

A

Neisseria meningitidis

4
Q

Name the three major bacteria causing meningitis in the elderly?

A

Neisseria meningitidis
Listeria monocytogenes
Strep pneumoniae

5
Q

What is the antibiotic of choice in a presentation of bacterial meningitis?

A

Cefotaxime (cephalosporin) = inhibits penicillin binding protein and hence prevents bacterial cell wall formation

6
Q

Name two classes of antibiotics effective against gram positive bacteria?

A

Penicillins - Amoxycillin//benzylpenicillin//fluclocaxacillin
Vancomycin

7
Q

Name two classes of antibiotics effective against gram negative bacteria?

A

Aminoglycoside - Gentamycin

Quinilone - ciprofloxacin

8
Q

What are the limitations of rifampicin?

A

Young females on the oral contraceptive pill will be at danger - Rifampicin induced the cytochrome P450 and therefore leads to the metabolism of oral contraceptives

9
Q

Which particular meningitis inducing bacteria is NOT sensitive to cefotaxine?

A

Listeria monocytogenes

10
Q

Late-onset syndrome of meningitis of a newborn is usually caused by what?

A

Bacteria transmitted from vaginal flora during parturition

11
Q

Early-onset syndrome of meningitis of a newborn is usually caused by what?

A

Passed in utero via placenta

12
Q

Which particular meningitis inducing bacteria in neonates are sensitive to cefotaxine?

A

Group.B streptococcus

E.coli