Critical Appraisal Flashcards

1
Q

What is critical appraisal of research?

A

Assessing validity of research and techniques employed in a study

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2
Q

What is internal validity?

A

How likely the results are to be true and free from bias when considering methodology

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3
Q

What is external validity?

A

Whether results can be generalised to a population

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4
Q

Name the 6 steps of critical appraisal

A

a. Are aims and question clearly defined?
b. Is methodology appropriate?
c. Is sample size determined?
d. Is statistical analysis appropriate?
e. Are conclusions based on results?
f. Can I apply to my own patients?

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5
Q

Describe how the aims should be stated during critical appraisal

A

Clearly stated and focused, suggesting hypothesis has been stated in advance, and using PICO

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6
Q

Name 2 types of research methodology

A

Descriptive and analytic

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7
Q

Name 2 types of descriptive research methodology

A

Survey and Cross Sectional

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8
Q

Name 2 types of analytic research methodology

A

Experimental and Analytic

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9
Q

Describe selection bias and how it is minimised

A

Difference in baseline characteristics
Randomization

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10
Q

Describe performance bias and how it is minimised

A

Difference in care provided
Blinding

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11
Q

Describe detection bias and how it is minimised

A

Difference in outcome determination
Blinding

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12
Q

Describe attrition bias and how it is minimised

A

Differences caused by withdrawals from study
Statistical methods

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13
Q

Describe 4 ways to control confounding factors

A
  1. Restriction
  2. Matching
  3. Randomisation
  4. Regression analysis
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14
Q

Describe sample size with regards to critical analysis

A

Larger usually is better

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15
Q

What should the power value be of a sample size?

A

80%

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16
Q

Describe why appropriate analysis is essential with regards to critical appraisal

A

Right tests for the data ensure the correct interpretation of results

17
Q

What is the major component of deciding whether research is applicable to your own patients?

A

External validity of the study

18
Q

Describe 4 ways external validity affects application of research to patients

A
  1. Similar populations
  2. Similar settings
  3. Have all outcomes been accounted for
  4. Pt values and beliefs