critical care concepts Flashcards
(58 cards)
What is the function of ventilation?
gas distribution into & out of the pulmonary airways
What is the function of pulmonary perfusion?
blood flow from the rt side of the heart, through the pulmonary circulation & into the lt side of the heart
What is diffusion?
gas movement from an area of greater to lesser concentration through semipermeable membrane
What is ventilation?
- gas distribution in & out of the airways
- assesses the status of CO2
How is blood oxygenated?
through perfusion
What is the perfusion rate of the body?
The alveoli receive O2 at ~ 4L/min and the capillaries supply blood at ~ 5L/min
- this makes the V/Q ratio 4:5 or .8 (NOT a 1:1 ratio)
- This is only an average because the VQ ratio varies based on the body position & regions of the lung
What happens when alveoli are less compliant?
we dont get as good of ventilation at the top of our lungs
What is shunting?
- problem with decreased ventilation
- alveoli perfused but not ventilated
- allows deoxygenated blood to go into the left side of the heart & into the body
What can cause shunting?
- congenital issues
- airway obstruction
- ARDS (acute resp distress syndrome)
- pneumonia
- atelectasis
- pulmonary edema
What is dead space?
- problem is decreased perfusion (think trachea)
- when there is NOT enough or is a problem with blood in the lung becoming oxygenated
What can cause dead space?
- pulmonary embolism
- pulmonary infarction
What is a silent unit (silent lung)?
- problem with ventilation & perfusion
- there is shunting & dead space
What can cause silent lung?
- ARDS (acute respiratory distress syndrome)
- pneumothorax
What is hypoxemia?
Low arterial oxygen tension (in the blood)
- adversely affects every tissue in the body
supply & demand mismatch
- poor perfusion such as in ischemia
- decreased arterial oxygen, such as anemia
How do tissues tolerate hypoxemia?
- skeletal muscle can recover after 30 minutes of hypoxemia
- brain cells can tolerate 4-6 min
- must provide oxygen until cause can be reversed
What does hypoxemia cause?
- depletion of ATP
- acidosis
- damage to cells from noxious stimuli (ie. poison)
- abnormal calcium from noxious stimuli → calcium is supposed to go in the cell & come right back out → if it stays in the cell it will cause problems (this can happen when the cells are damaged)
- inflammatory response
What is FiO2?
fraction of inspired oxygen (%); what is inhaled
- Room air is 21%
What is PaCO2?
The partial pressure of CO2 in arterial blood
- it is used to assess the adequacy of ventilation
What is PaO2?
The partial pressure of oxygen in arterial blood
- it is used to assess the adequacy of oxygenation
What is SaO2?
arterial oxygen saturation measured from blood speciment (an ABG)
What is SpO2?
arterial oxygenation saturation measured via pulse oximetry
What is hypercapnia?
increased amounts of carbon dioxide in the blood
What is hypoxia?
low oxygen level at the tissues
What is tidal volume?
The amount of gas moving in & out of the lungs with each breath, measured in milliliters (6-10 mL/kg)