Crude Drugs, Preparation And Its Evaluation Flashcards
(22 cards)
Are vegetable or animal drug that contains natural substances
Crude drugs
Crude drugs natural substances have undergone what process
Collection and drying
They are used as medicine for human being and animals internally and externally
Crude drugs
What is the importance of evaluation of crude drugs
To ensure identity of drugs and determine the quality and purity of drugs
It refers to the identification of biological source of drug
Identity
It refers to the quantity of active constituent present
Quality
It refers to the extent of foreign organic materials present in crude drugs
Purity
Main reasons of evaluation of crude drugs
•Biochemical variation
•Effect of treatment and storage
•Adulteration and substitution
Five methods of evaluation of crude drugs
•organoleptic evaluation
•microscopical evaluation
•chemical evaluation
•physical evaluation
•biological evaluation
Evaluation by means of organ of senses knowing the color odor taste size shape and special features like texture
Organoleptic evaluation
It refers to the study of form of drugs
Morphology
It refers to the study of description of form
Morphography
Evaluation for identification of pure powdered drug
Microscopic evaluation
It allows more detail examination of a drug and their identification by their known histological character
Microscopical evaluation
It is used to confirm the structural detail of drugs from plant origin
Microscope
Three types of microscopical evaluation methods
•Microscopic linear measurements
•determination of leaf constant
•quantitative microscope
A method of microscopical evaluation which includes size of starch grains, length and width of fibers and trichomes
Linear measurements
Two first scientists to investigate leave drugs for stomatal number and stomatal index
Timmerman and rowson
Is the average number of stomata per square millimeter of epidermis of the leaf
Stomatal number
Is the percentage which the numbers of stomach form to the total number of epidermal cells
Stomatal index