Crystalloids

Question 1

Isotonic Crystalloids

Answer 1

NS (Normal Saline 0.9%)
LR (Lactated Ringers)
Plasma-Lyte

Question 2

Isotonic Fluid Shift per 1L

Answer 2

Intracellular (ICF): 0mL
Extracellular (ECF): 1,000mL

Interstitial fluid: ~750mL (75%)
Intravascular fluid (Plasma): ~250mL (25%)

Question 3

Hypotonic Crystalloids

Answer 3

0.45% Normal Saline
D5W

Question 4

Hypotonic Fluid Shift per 1L

Answer 4

1 Liter of 0.45% NS distributes as:

Intracellular (ICF): 666mL (>/= 2/3)
Extracellular (ECF): 333mL (>/= 1/3)

of this 333mL:
Interstitial fluid: ~250mL
Intravascular (plasma): ~ 83mL
Only ~ 8% stays in the vascular space.

Question 5

Hypertonic Crystalloids

Answer 5

3% NaCl
D10 Dextrose

Question 6

Fluid Shift for Hypertonic Crystalloids per 1L

Answer 6

Fluid compartment approximate volume shift:
Intracellular (ICF): -250mL to-500mL (fluid pulled out of cells)

Extracellular (ECF): +1250mL to 1500mL total
-interstitial fluid ~750-900mL
-intravascular (plasma)~500-600mL