CT Disorders

Question 1

Rheumatoid arthritis

Answer 1

• chronic disease that causes inflammation of joints
• Autoimmune disorder causing joint pain, stiffness, decreased motility and fatigue
• Usually affects hands, feet, knees, and shoulder

Question 2

Lupus

Answer 2

• autoimmune disorder causing tissue damage
• Often affects heart, lungs, kidneys, brain
• Sx come and go with flare-ups and periods of remission
• No cure

Question 3

Marfan syndrome

Answer 3

• systemic inherited disorder affecting CT
• Pts tend to be tall and thin with long arms and legs
• Shows with extremely flexible joints and curved spines
• Complications may occur when cardiovascular tissue is affected leading to heart murmurs or aortic aneurysms

Question 4

Fibrodysplasia ossificans progressiva (FOP):

Answer 4

• rare condition turning muscle and CT to bone
• Autosomal dominant disorder caused by mutation in ACVR1 gene
• Children usually have malformed big toes
• Debilitating and leaves patients immobile