Current Institutional Commitments

Question 1

Center for Multiple Myeloma Nanotherapy (CMMN) Pilot and Supplement

Answer 1

Achilefu, Sam (8 - OIP)

Innovative approaches to multiple myeloma and bone metastasis.

Question 2

Leukemia SPORE

Answer 2

Link, Daniel (4 - HDMP)

Translational science SPORE to create clinical practices which have resulted in several first-in-human therapeutic clinical trials for leukemia.

Question 3

Pancreatic SPORE

Answer 3

Hawkins, William (3 - TIP)

Key projects in pancreas cancer imaging, immunotherapy, and small molecule drug development. Significant SPORE-to-SPORE interactions.

Question 4

U54 PDX

Answer 4

Fields, Ryan (11 - STTP)

Project to create a network of academic cancer centers that are capable of testing PDX (tumor tissue on mouse) models to match best treatments with individual patients.

Question 5

U2C Human Tumor Atlas Network (HTAN)

Answer 5

Fields, Ryan (11 - STTP)

Project to create comprehensive tumor atlases for pancreatic, triple negative breast, and glioblastoma cancers for the purpose of examination at the time of diagnosis and throughout treatment to uncover treatment response, resistance, and metastatic progression.

Question 6

Evans Myelodysplastic Syndromes (MDS)

Answer 6

Walter, Matthew (4 - HDMP)

Project to support clinical and research initiatives for MDS (preleukemia) as our understanding evolves over time.

Question 7

CDC Prevention

Answer 7

Brownson, Ross (6 - PCP)

Collaborative project with the CDC, WU Schools of Social Work, WUSM, SCC, local health departments, state and national orgs addressing health equity.

Question 8

P50 Implementation for Cancer Control

Answer 8

Colditz, Graham (6 - PCP; 9 - BCRP)

Washington University Implementation Science Center for Cancer Control (WU-ISCCC) is aimed at addressing cancer disparities by increasing appropriate screenings in areas of highly impoverished and underserved populations.

Question 9

UM1 Experimental Therapeutics Clinical Trials Network (ETCTN)

Answer 9

Park, Haesong (11 - STTP)

Project to allow WUSM to continue enrolling patients to innovative early phase trials, developing investigator-initiated trials using CTEP (Cancer Therapy Evolution Program) agents, and monitoring junior faculty on clinical research.

Question 10

U24 Imaging

Answer 10

Shoghi, Kooresh (8 - OIP)

This initiative bridges the gap in preclinical and clinical studies of triple negative breast cancer (TNBC) and has the potential to serve as a launchpad for similar initiatives at WUSM.