cyps Flashcards

1
Q

CYP1A2 substrate (4)

A

tricyclics

olanzapine, clozapine, haldol

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2
Q

CYP1A2 inhibitor (2)

A

fluvoxamine

duloxetine

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3
Q

CYP1A2 inducer (1)

A

tobacco

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4
Q

CYP 2D6 substrate(9)

A

tricyclics, thioridazine
venlafaxine, duloxetine, wellbutrin
haldol, clozapine, olanzapine, risperidone

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5
Q

CYP2D6 inhibitor (4)

A

fluxoetine, paroxetine, duloxetine, sertraline, citalopram, lexapro

TCAs

methadone

perphenazine

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6
Q

CYP2D6 inducer (2)

A

dexamethasone, rifampin

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7
Q

CYP2C9 substrate (2)

A

warfarin, phenytoin

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8
Q

CYP2C9 inhibitor (2)

A

fluoxetine, fluvoxamine

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9
Q

CYP2C19 substrate (4)

A

tricyclics, propranolol, omeprazole, diazepam

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10
Q

CYP2C19 inhibitors (3)

A

fluvoxamine
fluoxetine
venlafaxine

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11
Q

CYP2C19 inducers (1)

A

carbamazepine

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12
Q

CYP3A4 substrate (10)

A
OCP
Z drugs
benzos
haldol, abilify
dilt, nefedipine
tamoxifen
erithryomycin
statin
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13
Q

CYP3A4 inhibitors (6)

A
fluoxetine, fluvoxamine
grapefruit juice
antifungals
ca channel blockers
cimetidine
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14
Q

CYPA3A4 inducers (4)

A

phenytoin
rifampin
oxcarb
carbamazepine

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