Cyst of the jaw Flashcards
(47 cards)
what is a cyst
pathologicalcavity filled with fluid, semi fluid or gasous content. Not created by pus accumulation
how are cysts classified
- epithelial lined (most)
- odontogenic/non odontogenic
- inflam/developmental
appropriate further inv of a cyst
plain Rg - OPT/PA/occ
other views - occipitomental/PA mandible
CBCT
should a biopsy be taken - how
describe cystic fluid
wide bore needle - FNA
blood/cystic fluid/air/pus
-clear straw coloured fluid (crystals present)
what is the purpose of an incisional biopsy - when
- how
to take a sample of cyst lining for histological analysis
- during marsupilisation
- usually under L.A.; select place where “cyst” appears superficial; raise mucoperiosteal flap; remove bone as required – using rongeurs or a round bur; incise and remove a section of lining
name the types of cysts of the jaw
odontogenic
- radicular
- dentigerous
- keratocyst (keratocystic odontogenic tumour)
non odontogenic
- nasopalatine
- stafne cavity
- aneurysmal bone cyst
sources of epithelium for odontogenic cysts
- rests (debris)of malassez, hertwig’s root sheath
- rests of serres - lamina remnants
- reduced enamel ep
radicular cyst
- what
- synonyms
- aetiology
- features
periapical cyst attached to the apex of a NV tooth
inflammatory origin = pulpitis then PA granuloma then cyst
- periapical/dental cyst
-slow painless swelling, no symps until big enough to be noticed
-at first = hard and rounded, later eggshell thickness and cracking on pressure. Eventually wall resorbed leaving soft bluish swelling.
- originate from rests of malassez (hertwig’s root sheath)
radicular cyst - histology
epithelial lining (often incomplete), CT capsule,
plasma cells and macrophages - inflammation
-peripherally osteoclasts allow bony expansion, osteocblasts react to inflammation by depositing bone causing corticated margin.
name 2 variations of a radicuar cyst
residual cyst
inflamatory lateral periodontal cyst
what is a dentigerous cyst
a developmental cyst surrounding the crown of an unerupted tooth
who and where are dentigerous cysts most likely to occur
male>female
mandible>max
Lower 8’s and up 3’s
histology of a dentigerous cyst
thin non keratinised stratified squamous epithelium
- arises from separation of reduced enamel epithelium and fromation of follicular space - internal pressure causes expansion of this
clinical features of dentigerous cyst
Rg features
- grow by internal pressure - expansion and displacement of adjacent structures. Slow growing
- developmental but can be caused by inflammation of pericoronitis/adjacent NV teeth.
- Rg - circumscribed, rounded and unilocular. Contain crown of tooth.
what condition can appear with multiple dentigerous cysts
name one other feature of this condition
cleidocranial dysplasia
partly missing collarbones = hypermobility
prognathic mandible
hyperdontia - many supernumeraries
measurements of dentigerous cyst and follicle
-<2.5mm = follicle
-> 4.2mm = probable cyst
>10mm - definite cyst
asymmetrical radiolucency = cyst
what is an odontogenic keratocyst
who
clinical presentation
developmental cyst m>f mostly mandible -third molar and ramus multilocular - symptomless until infected recurrence issue
cyst aspirate of a keratocyst
histology
white keratin - contains sqaumes - low soluble protein content
-parakeratosis of cyst lining, basal palisading
why is recurrence likely to occur for a keratocyst
thin friable lining - left behind
many daughter cysts missed
cell nests
what syndrome is associated with multiple keratocysts
other features
gorlin-goltz syndrome (basal cell naevus)
autosomal dominant
skeletal abnormalities and basal cell carcinomas
-frontal & temporalparietal bossing hypertelorism
mild mandibular prognathism
Abnormalities of Ca & PO4 metabolism
appearance of a keratocyst on a Rg
growth pattern
well defined radiolucent area, scalloped margin , usually ramus/3rd molar, sharply demarcated
- pattern = extensive spread forwardand backward along medullary cavity. MINIMAL expansion
AP growth
pathogenesis of an odontogenic keratocyst
develop from rests of odontogenic epithelium left after tooth development - eg rests od serres
-Mutation/deletion/inactivation of ptch gene (tumour suppressor gene)
nasopalatine cyst
origin
where
presentation
found in midline - incisive canal
- epithelial reminants of nasopaltine duct
- dependant on canal affected - superficial soft tissue cyst, can grow primarily into nose - salty discharge
what differentiates odontogenic and non odontogenic cysts
distibution of cytokeratin in cyst epithelium