Cytochemistry Flashcards

1
Q

Specific esterase

What is it positive in

A

Positive in myeloid cells

In AMML myeloblasts are red with specific

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2
Q

Non specific esterase

A

Positive in monocytes

In AMML, monoblasts are blue with nonspecific

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3
Q

Periodic Acid Schiff (PAS)

What is positive, what is negative?

A

Positive in lymphoblasts (ALL) and erythroblasts (AEL, DiGuglielmo’s)

Normal erythroblasts will be negative

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4
Q

Leukocyte Alkaline Phosphatase (LAP)

A

Positive in leukemoid reactions

NOT in neoplasms, NOT in CML

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5
Q

Tartrate Resistant Acid Phosphatase (TRAP)

A

Positive in hairy cells

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6
Q

Terminal Deoxynucleotidal Transferase (TdT)

Method of interpretation?

A

Positive in most acute lymphocytic leukemia ALL
Interpreted with immunofluorescence

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