Cytochrome p450

Question 1

What is the acronym for drugs that are metabolised by cytochrome p450?

Answer 1

5COW P(2)A(2)T(2)S PTSDD

Question 2

What are the anti convulsant drugs that are metabolised by cytochrome p450?

Answer 2

Carbamazepine and phenytoin

Question 3

What anticoagulant drug is metabolised by p450?

Answer 3

Warfarin

Question 4

What contraceptive drug is metabolised by p450?

Answer 4

oral contraceptive

Question 5

What immunosuppression drugs are metabolised by p450?

Answer 5

Ciclosporin

Tacrolimus

Question 6

What is the acronym for drugs that induce p450?

Answer 6

CRAP GPS

Question 7

What is the anti convulsant drugs that induce p450?

Answer 7

Carbamazepine and phenytoin

Question 8

What antiviral drug is metabolised by p450?

Answer 8

Protease inhibitor

Question 9

What antibiotic induce p450?

Answer 9

Rifmapicin

Question 10

What is the action of alcohol on p450?

Answer 10

Chronic alcohol induces p450

Acute bing alcohol inhibits p450

Question 11

What flowering part induces p450?

Answer 11

St jon Wart

Question 12

What antihypertensive medication is metabolised and inhibitor of p450?

Answer 12

Diltiazem (calcium channel blocker)

Question 13

What pain medication is metabolised by p450?

Answer 13

Painkiller/paracetamol

Question 14

What abx is metabolised by p450?

Answer 14

Metronidazole

Question 15

What is the acronym for inhibitors of p450?

Answer 15

SICK FACES. COM GROUP

Question 16

What anticonvulsant inhibit p450?

Answer 16

Sodium valproate

Question 17

What cholesterol controlling is metabolised by p450?

Answer 17

Statin

Question 18

What non drug substances induce p450?

Answer 18

Put in your mouth= Charcoal meat and cigarettes

Question 19

What respiratory drug is metabolised by p450?

Answer 19

Theophylline

Question 20

What are the antibiotics that are inhibit of p450?

Answer 20

Ciprofloxacin 
Sulphonamides
Chloramphenicol
Isoniazid
Metronidazole 
Erythromycin

Question 21

What anti depressants are metabolised by p450?

Answer 21

Citalopram= SSRI

TCA

Question 22

What alzheimer drug is metabolised by p450?

Answer 22

Acetylcholine inhibitor = donepezil

Question 23

What type of steroids is metabolised by p450?

Answer 23

Corticosteroids

Question 24

Give example of a drug given for alcohol withdrawal that is metabolised by p450?

Answer 24

Diazepam (BZDP)

Question 25

What diabetic drug induces p450?

Answer 25

Sulphonylureas

Question 26

What anti fungal drug induces p450?

Answer 26

Griseolfine

Question 27

What drugs that regulate stomach acid production is metabolised by p450?

Answer 27

PPI

Question 28

What drugs that regulate stomach acid production inhibits p450?

Answer 28

``` Cimetidine = H2 antagonist Omeprazole= PPI ```

Question 29

What antifungals inhibits p450?

Answer 29

Ketoconazole | Fluconazole

Question 30

Juice of what fruit inhibits p450?

Answer 30

Grape fruit juice

Question 31

What anticoagulant drug is activated by p450?

Answer 31

Clopidogrel

Question 32

What potassium channel blocker drug is metabolised by p450 and inhibits p450?

Answer 32

Amiodarone

Question 33

What vitamins are metabolised by p450?

Answer 33

Vitamin D/ca

Question 34

What thyroid drug is inhibitory of p450?

Answer 34

Thyroxine

Question 35

What rate rhythm drug is metabolised by p450?

Answer 35

digoxin

Question 36

What old school epileptic drug is inducer of p450?

Answer 36

Phenobarbitone