Cytokines Flashcards
(12 cards)
1
Q
IL-2
A
T-cell activation (CD4, CD8, and Treg)
2
Q
IL-3
A
Bone marrow growth & differentiation
3
Q
IL-4
A
IgE class switching
4
Q
IL-5
A
IgA class switching Eosinophil activation
5
Q
IL-6
A
Fever
Acute phase protein production
6
Q
IL-8
A
Neutrophil chemotaxis
7
Q
IL-12
A
NK cell activation
Differentiation of immature T-cells to Th1 cells
8
Q
IL-13
A
IgE class switching
9
Q
TNF-a
A
Activates endothelium
Leukocyte recruitment
Vascular leakage
(Septic shock)
10
Q
IFN-g
A
NK cell activation
Increase MHC expression on APCs
(Antiviral/antitumor)
11
Q
IL-10
A
Decreases inflammatory response
12
Q
IL-1
A
Fever Acute inflammation Osteoclast activation Leukocyte recruitment Endothelium adhesion molecule expression
