Cytoskeleton Flashcards

1
Q

Cytoskeleton components

A

1) microfilaments
2) intermediate filaments
3) microtubules

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2
Q

Microfilaments

A

Maintain cell shape

Made of actin

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3
Q

Intermediate filaments

A
More permanent structures 
Variable composition (keratin, Lamin)
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4
Q

Cytoskeleton

A
  • structural support
  • locomotion
  • intercellular anchor
  • involved in mitosis
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5
Q

Microtubules

A
  • Motility (cilia,flagella), cell division

- made of Tubulin

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6
Q

The structural role of microfilaments

A

Bear tension, resisting pulling forced within the cell

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7
Q

What is the cortex

A

A 3D network inside the plasma membrane to help support the cells shape made out of microfilaments

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8
Q

Core of Microvilli of intestinal cells is made of

A

Made up of bundles of microfilaments

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9
Q

Microfilaments that function in cellular motility contain ?

A

The protein myosin in addition to actin

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10
Q

Amoeboid movement

A

Produced by the localized contraction brought about by actin and myosin

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11
Q

Pseudopodia (Cellular extensions )

A

Extend and contract through the reversible assembly and contraction of actin subunits into microfilaments

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12
Q

Cytoplasmic streaming

A

Circular flow of cytoplasm within cells, speed distribution of materials within the cell.

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13
Q

Function of intermediate filaments

A

Support cell shape and fix organelles in place

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14
Q

Hollow rods of 25 in diameter and 200nm to 25 microns long

A

Microtubules

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15
Q

Microtubules functions

A

Shaping cell
Guiding movement of organelles
Separating chromosomes during cell division

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16
Q

Types of Tubulin

A

B-Tubulin

Alpha-Tubulin

17
Q

Centrosome

A

Microtubules-organizing center.

In animal cells the centrosome has a pair of centrioles each with nine triplets of microtubules arranged in a ring

18
Q

What controls the beating of Cilia and flagella

A

Microtubules

19
Q

Common structure of cilia and flagella ?

A

A core of microtubules sheathed by the plasma membrane

  • basal body that anchors cilium or flagellum.
  • motor protein called dynein which drives the bending movements of a cilium or flagellum.
20
Q

Microfilaments structure

A

Two intertwined strands of actin, each a polymer of actin subunit

21
Q

Microfilaments diamer and subunit

A

7 nm diameter and subunit is actin

22
Q

Microfilaments (actin filaments) functions

A
  • maintenance of cell shape.
  • changes in cell shape
  • muscle contraction
  • cytoplasmic streaming
  • cell motility ( as in pseudopodia)
  • cell division (cleavage furrow formation)
23
Q

Intermediate filaments structure

A

Fibrous proteins supercoiled into ticker cables

24
Q

Intermediate filaments diameter ? Subunits?

A

8-12nm

Protein subunit: several different proteins depending on cell type example : keratins

25
Q

Main functions of intermediate Filaments ?

A
  • Maintenance of cell shape (tension bearing elements)
  • anchorage of nucleus and certain other organelles
  • formation of nuclear lamina
26
Q

Microtubules (Tubulin polymers) structure ?

A

Hollow tubes; walls consist of 13 columns of Tubulin molecules.

27
Q

Microtubules diameter and protein subunit?

A

25 nm w/ 15nm lumen

Subunits: Tubulin a dimer consisting of alpha-Tubulin and B-Tubulin

28
Q

Microtubules functions ?

A

Maintenance cell shape
-cell motility as in cilia or flagella
-chromosome movements in cell division
Organelles movements