Cytoskeleton

Question 1

Cytoskeleton

Answer 1

Network of polymers in the cytoplasm

Question 2

Purpose of the cytoskeleton

Answer 2

Structural support and locomotion

Question 3

Microtubules

Answer 3

Largest structural elements of the cytoskeleton made of microtubules

Question 4

2 main functions of microtubules:

Answer 4

1. Long distance intracellular transport

2. Cellular locomotion

Question 5

Protein that makes up microtubules

Answer 5

Tubulin

• Alpha has a negative charge
• Beta has a positive charge

Question 6

Centrosome

Answer 6

Where microtubules are organized

basal bodies for flagella

Question 7

How do microtubules form?

Answer 7

Reversible polymerization of tubulin dimers

Question 8

Three basic types of cytoskeletal elements

Answer 8

1. Microtubules
2. Microfilaments
3. Intermediate filaments

Question 9

Why are microtubules dynamically unstable?

Answer 9

Because the assembly and disassembly at the ends of the microtubule

Question 10

GTP Hydrolysis

Answer 10

• Tubulin dimers bind GTP

- GTP hydrolyzed to GDP after polymerization

Question 11

Composition of microfilaments

Answer 11

Actin (abundant protein)

Question 12

Function of microfilaments

Answer 12

Control cell movement and shape

Question 13

ATP dependent motors

Answer 13

Move along actin fibres or use actin fibres to exert force

Question 14

Function of intermediate filaments

Answer 14

Bearing tension