DATA INTERPRETATION

Question 1

Microcytic anaemia causes

Answer 1

Iron deficiency
Thalassaemia
Sideroblastic anaemia

Question 2

Macrocytic anaemia causes

Answer 2

B12/folate deficiency
Excess alcohol
Liver disease
Hypothyroidism
Haematological diseases beginning with ‘M’ - myeloproliferative, myelodysplastic, multiple myeloma

Question 2

Normocytic anaemia causes

Answer 2

Anaemia of chronic disease
Acute blood loss
Haemolytic anaemia
Renal failure (chronic)

Question 3

What drugs cause neutropenia and neutrophilia?

Answer 3

Neutrophilia - steroids

Neutropenia - clozapine and carbamezapine

Question 4

What drugs cause thrombocytopenia (low platelets)?

Answer 4

Penicillamine
Heparin

Question 5

Warfarin + major bleed management

Answer 5

Stop warfarin
Give 5-10mg IV vit K
Give prothrombin complex

Question 6

Target INR on warfarin for most people

Answer 6

2.5-3.5

Question 7

INR 5-8
- no bleeding
- minor bleeding

Answer 7

INR 5-8
- no bleeding: omit warfarin for 2 days then reduce dose
- minor bleeding: omit warfarin and give 1-5mg of vitamin K IV

Question 8

INR >8
- no bleeding
- minor bleeding

Answer 8

INR >8
- no bleeding: omit warfarin and give 1-5mg PO vitamin K
- minor bleeding: omit warfarin and give 1-5mg of vitamin K IV

Question 9

Hyponatraemia causes

Answer 9

Carbamezapine
Thiazide-like diuretics e.g. furesomide
Loop diuretics