Day 1: Anatomy, morphology, pathophysiology Flashcards
(56 cards)
What is the major barrier of the skin
Epidermis
What are the 3 major nerve fibers in the skin
Ab fibers- large, heavily myelanated, tactile sensation
Adelta fibers- thin, myelinated nerve fibers, transmission of short and fast stimuli
C- unmyelinated, transmit pain and itch
Normal cell division occurs in which layer
Basal cell layer
How long does skin live? Where does it start/end?
Starts in basal layer, take 2 weeks to migrate to granular, 2 weeks to shed across stratum corneum
Which layer is just superficial to the basal layer
Stratum spinosum
Composed of keratinocytes
What cells produce karatin and what is keratin
Keratinocytes produce keratin
Fibrous protein that is a component of stratum corneum
What gives the stratum spinosum its name
Spines (bridges) that connect keratinocytes in stratum spinosum
Granular cells contain what
keratohyalin
What is the major physical barrier of the skin
Stratum corneum
Which cells protect the skin from UV light
Melanocytes (in epidermis)
Describe blood flow to the epidermis
Epidermis does not have an intrensic blood supply, so depends on diffusion of nutrients and o2 from vessels in the papillary dermis
Apocrine vs Eccrine glands
IN DERMIS
Apocrine- sweat glands depend on androgens for their development (Wake up at puberty). Sebaceous glands are also under androgen control (Oil).
Eccrine glands- Help regulate body temperature (sweat glands)
Describe tonicity of eccrine sweat glands
Sweat is isotonic to plasma, but becomes hypotonic by the time it exits the skin because of reabsorption of electrolytes (dont want to loose all of the electrolytes)
Which muscle gives the goose pump apperance on the skin
arrector pilli muscle
Hyponychium
where nail meets tip of finger, junction at end of nail/finger
Where is matrix
Under skin, proximal to proximal nail fold
Macule if small, patch if bigger. Not raised
Papule
Plaque
Wheal– papule or plaque- uticaria
Nodule
Vesicle <.5, Bulla if >.5
pemphigus vulgaris
Cyst- filled with pus or keratin, >.5
Staph boil
Scale– flake composed of stratum corneum, hyperkeratotic (Psoriasis)
