Deck 1

Question 1

Inhalant intoxication causes what symptoms and what is “glue sniffers rash” ?

Answer 1

Ataxia,euphoria,lethargy and loss of consciousness which resolves within 45 mins.
It also presents with perinasal and perioral rash which is glue sniffers rash.

Question 2

Methadone is metabolized by CYP3A4
Which drug class causes sedation,bradynea, and miosis and inhibits CYP3A4 leading to methadone toxicity?

Answer 2

Azoles (fluconazole,ketoconazole)
Ciprofloxacin
Clarithromycin
Cimetidine

Question 3

Features of learning disorder?

Answer 3

Problems in reading,writing and mathematics

Question 4

REM sleep behavior disorder causes accumulation of which protein resulting in which disease?

Answer 4

Alpha-synuclein protein resulting in Parkinson’s disease.
Occurs in men over 50.

Question 5

What is first line treatment for specific phobia and give examples of it?

Answer 5

CBT (cognitive behavioral therapy) is first line treatment
Examples are fear of flying,heights,blood,injections,animals

Question 6

Which drug class causes urinary retention,constipation,(anti-cholinergic properties) ?

Answer 6

TCA eg (amitryptaline)

Question 7

MDD with psychotic features treated with what 1st line treatment?

Answer 7

ECT

Question 9

TCA mechanism of action?

Answer 9

1.Dopamine and norepinephrine reuptake inhibition
2.Sodium channel inhibition

Question 10

Features of obstructive sleep apnea?

Answer 10

Obesity
Daytime sleepiness/somnolence
Repetitive awakenings
Snoring

Question 11

How many weeks are adequate for anti-depressants to take effect?

Answer 11

4-6 weeks