Deck 1 Flashcards
(104 cards)
Behcet Disease
typically presents with multiple oral and genital ulcers that are painful and recurrent. Uveitis commonly occurs
Felty syndrome
this is advanced RA that is associated with neutropenia and splenomegaly
What may present with arthritis that is symmetric, migratory and non-erosive, with a very brief period of morning stiffness (shorter than morning stiffness of RA)?
SLE
FATRN
thrombotic thrombocytopenic purpura – decreased ADAMTS13 activity. F-fever, A -hemolytic anemia, T-thrombocytopenia (non-palpable purpura), R-renal injury, N-neurologic findings (confusion, stroke)
Mixed cryoglobulinemia syndrome – what is it associated with? how does it present (5)? labs show?
caused by immune complex deposition in small- to medium-size blood vessels.
Associated with chronic Hepatitis C.
Presents w/ fatigue, PALPABLE purpura, arthralgias, renal disease (hematuria, proteinuria, glomerulonephritis), and peripheral neuropathies.
Lab studies show serum cryoglobulins, hypocomplementemia, +RF, elevated transaminases, and kidney injury
acute massive PE, what will pulmonary artery catheterization show?
elevated RA pressure, elevated Pulmonary artery pressure, NORMAL pulmonary capillary wedge pressure
hypovolemic vs cardiogenic shock, pulm artery catheterization will show?
hypovolemic: decreased RA pressure, PA pressure, and PCWP. cardiogenic: INCREASED RA pressure, PA pressure, and PCWP.
what conditions can you see pulsus paradoxus in?
exaggerated fall in systemic BP > 10 mm Hg during inspiration. frequently seen in cardiac tamponade, may also be seen in severe asthma or COPD
Benzo overdose
slurred speech, unsteady gait, and drowsiness. pupil size is normal (2-4mm bright light, 4-8mm dark light) and there is only mild respiratory depression
Lithium toxicity
tremor and hyperreflexia, ataxia and seizures
Presbycusis
age-related hearing loss! progressive b/l symmetric hearing loss - it’s predominantly high-frequency sensorineural hearing loss that occurs over years. Pts hear well in one-on-one convos, but competing noise causes a decline. overtime subjective bilateral tinnitus can develop too
ototoxic meds?
aminoglycosides (streptomycin) and loop diuretics (furosemide, bumetanide)
Seborrheic dermatitis
causes pruritic, erythematous plaques with fine, loose, yellow, and GREASY-looking plaques, that predominantly affect the scalp (dandruff) and face (primarily affects areas w/ many sebaceous glands). common at age 1 and 30-60 yo. associated w/ Parkinson dz and HIV. Tx = Topical antifungals (selinium blue shampoo 1st).
Reversible causes of asystole/pulseless electrical activity (5 Hs & 5 Ts)
5 Hs: Hypovolemia, Hypoxia, Hydrogen ions (acidosis), Hypokalemia or hyperkalemia, Hypothermia. 5 Ts: Tension pneumothorax, Tamponade or cardiac, Toxins (narcotics, benzos), Thrombosis (pulmonary or coronary), Trauma.
Electrical alternans (varying amplitude of the QRS complexes) is a pathognomonic ECG finding for??
Pericardial effusion!! -it is due to the swinging motion of the heart in the pericardial cavity that causes a beat-to-beat variation in QRS axis and amplitude
PDE-5 inhibitors (sildenafil) used to tx erectile dysfunction can cause hypotension, especially in patients taking what?
alpha blockers (doxazosin) or nitrates
Rectangular, envelope-shaped calcium oxalate crystals in the urine are classically seen in pts who have ingested what?
Ethylene glycol! (antifreeze ingestion) – acute renal failure is the major complication
Hemodynamically stable pts with new onset A Fib can receive rate control with what meds?
beta blockers, Diltiazem (CCB), or digoxin
Tx for polycythemia vera?
serial Phlebotomy
What is the most common cause of symptomatic hyperoxaluria and oxalate stone formation?
Increased absorption of oxalate – Ca normally binds oxalate in the gut and prevents its absorption. in pts w/ Crohn’s or other conditions resulting in fat malabsorption, Ca is preferentially bound by fat and oxalate is left unbound and is free to be absorbed into the bloodstream
What meds are recommended to reduce the risk of stent thrombosis after intracoronary drug-eluting stent placement?
long-term dual antiplatelet therapy with ASPIRIN and Platelet P2Y12 receptor blocker (CLOPIDOGREL, prasugrel, ticagrelor)
For a normal distribution, 95% of all values are within __ standard deviations from the mean.
2 standard deviations
What tx for hyperthyroidism (Grave’s disease) can worsen the ophthalmopathy?
Radioactive iodine tx! Grave’s ophthalmopathy is due to the effects of activated T cells and thyrotropin receptor Abs (TRAB) on TSH receptors that are located on retro-orbital fibroblasts and adipocytes. Radioactive iodine tx can raise titers of TRAB and worsen the ophthalmopathy.
How do superior pulmonary sulcus tumors (Pancoast tumors) present?
Referred Shoulder pain! other common findings include Horner syndrome (ipsilateral ptosis and miosis) and radicular pain, paresthesias, or weakness of the ipsilateral arm due to invasion of the brachial plexus.