Deck 2 Flashcards

(64 cards)

1
Q

Antimicrobial stewadship

A

If appropriate narrow spectrum antibiotic found on S/S - change from initial empiric broad spectrum

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2
Q

Vibrio vulnificus

A

eating raw shellfish or trauma associated with contaminated seawater - hemorrhagic bullae, necrotizing fascitis, worse with liver dz/hemochromatosis (inc iron, inc growth),

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3
Q

Babesia

A

deer tick (Iox), NE/mE US, flu like sx, intraerythrocytic parasite, maltese cross, no rash, splenic rupture

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4
Q

Capnocytophagia

A

dog or cat bite - GNR

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5
Q

Rickettsia

A

RMSF - rash - palm, soles, wrists/ankles first

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6
Q

Smallpox exposure

A

smallpox vacccine w/in 3 days - buccal/pharyngeal rash - same stage crops, respiratory spread - widespread outbreak - can tx with cidofovir

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7
Q

Tacrolimus toxicity

A

tacrolimus levels increased by macrolide drugs/azole agents - inc cr, BUN

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8
Q

West Nile Virus

A

Myelitis - asymmetric flaccid paralysis, weakness

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9
Q

Middle aged woman, chronic cough, MAC on culture, no pre-existing lung dz, no systemic sx, neg acid fast smear

A

repeat acid fast smear - need to confirm dx as don’t want to treat colonization

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10
Q

Cryptococcal Meningitis - HIV immune reconstitution syndrome

A

Meningitis after initial HIV therapy - dramatic inflammatory response after immune system comes back - cryptococcus likely, +crypto Ag in CSF, - amphot B + fluconazole (oral)

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11
Q

CMV meningitis

A

only if CD4<100

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12
Q

Toxoplasmosis

A

multiple ring enhancing lesions on MRI, CD4<100

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13
Q

Histoplasmosis

A

Ohio/Missippi River valley - acute pulmonary dz +- CNS

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14
Q

HSV 2 Aseptic Meningitis

A

fever, vomiting, h/a, photosensitivity, normal CSF glucose, CSF gram stain neg

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15
Q

Bechets

A

painful oral/apthous ulcers/gential ulcers, uveitis

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16
Q

Erythema Migrans

A

if no cardiac or neuro sx then oral doxycycline - don’t test for lyme with EM rash

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17
Q

Benign recurrent lymphocytic Meningitis/ Mollaret Meningitis

A

CSF PCR for HSV-2 - have 2-10 episodes of meningitis - recover without tx, h/a, fever, neck stiffness, lymphocytes on CSF analysis - transient neuro sx (sz, halluc, diplopia)

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18
Q

Cryptococcal Meningitis

A

conventional amphotericin B + flucytocine - skin lesions present - decreased leukocytes, +crypto titers - can also tx with amphotericin B + fluconazole, fluconaz + flucytocine - DO NOT tx with caspofungin - lipid form of amphotericin if CRI/AKI

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19
Q

PID - outpt

A

ceftriaxone single dose + doxy x 14 days - cervicitis + signs of PID - (cervical motion tenderness, adnexal tenderness, uterine tenderness) - if systemic then clinda + gentamycin

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20
Q

Genital Herpes simplex

A

Dx - PCR of fissure/lesion - recurrent genital itching, burning,

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21
Q

Lymphogranuluma Verenum (LGV)

A

genital ulcer with lymphadenopathy + fever/malise - PAINLESS ulcer - check Chlymdia serology L1,L2,L3

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22
Q

Candial vulvovaginitis

A

KOH Wetmount

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23
Q

Syphillus Cancre

A

PAINLESS - single nodule - raised border - homosexuals, - check RPR, darkfield,

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24
Q

Chancroid

A

single or multiple PAINFUL lesions, ragged border, purulent exudate

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25
DGI - disseminated gonnococcal infection
PCR for neisseria gonnorrhea - arthrtisis-dermatitis syndrome - assymetric joint involvement
26
Pulmonary histoplasmosis
mild PNA - no tx with healthy host - Ohio/Mississippi river valley - non-prod cough/fever - if needed use itraconazole, if severe amphotericin B (lipid)
27
Catheter associated UTI
maintain bag below level of bladder - prevent backflow/stagnation - DO NOT NEED cleaning, tx of asyptomatic bactiuria or antibx coated catheters, or routine changing of catheter
28
Dx of UTI (catheter associated)
>10^3 CFU, signs/sx UTI (new onset fever, dysuria, lethargy, malaise)
29
newly dx HIV
Start HAART without sx if CD4<500 -
30
CAP outpt
young pt with no risk factor for drug resistent S Pneumo - tx with azithro (macrolide)
31
Coccoidiomycosis
SW US - pulm dz and erythema nodosum - elev ESR - hilar lymphadenopathy
32
Blastomycosis
Ohio/Mississippi River valley - PNA+erythema nodosum - itraconazole
33
Histoplasmosis
Ohio/Mississippi River valley - PNA only itraconazole
34
Acute, uncomplicated cystitis
nitrofurantoin or bactrim (if no sulfa allergic)
35
Tuberculous Pericarditis
Pericardiocentesis - 4 drug regimen and PREDNISONE
36
Prevent hospital acquired infections
hand hygene
37
Osteomyelitis
can't get MRI 2/2 ICD - use CT scan if not 3 phase bone scan
38
Malaria P. Falciparum
most deadly form - only immature ring forms inside RBCs
39
P. Ovale/Vivax
Should see all forms (trophoids, schiffer dots and immature forms) in RBCs
40
P. Malariae
fever q72hr, + band form (trophozoite)
41
Active TB - pt d/c'd meds
if d/c'd >2 wks start tx all over
42
Extrapulm Blastomycosis (ie skin, genital lesions)
Itraconazole - see yeast/buds in microscopy
43
Influenza tx
only if started 2 days into sx - oseltamavir, zanamavir (DO NOT USE amantadine or rimandatine - resistance high)
44
Pyrazinamide side effects
acute gout - hyperuricemia - inhibit excretion of uric acid
45
Isonazid side effects
hepatitis, rash, peripheral neuropathy, lupus like syndrome
46
Rifampin
orange body fluids, hepatitis, rash, GI upset
47
Drug resistant Pseudomonas
Colistin IV - GN bacteria
48
Hospitalized patient with bacteremic pneumococcal PNA
d/c on 7 day oral abx after swithing to oral - no need to observe if stable already
49
Anthrax
bacillus anthracis - flu like syndrome, widened mediastinum - rapid septic state - mediastinal LN get infected from inhalational anthrax - hemorrhage - shows widended mediastinum
50
Asymptomatic patient with blasto in stool
diarrhea resolved w/in 24 hrs no further tx needed
51
Sporadic Creutzfeldt-Jakob Disease
prionosis - rapid dementia, myoclonus, bland CSF, nondx MRI, spongiform biopsy brain, period sharp wave on EEG, 14-3-3 protein on CSF
52
CA-MRSA PNA
no risk factors for HCAP (so no zosyn) - tx CAP + treat for MRSA (vanc) - see cavitary lesions - after flu - superinfxn - improved then suddenly worse
53
Botulism
Triad - symmetric descending paralysis, bulbar palsy (diplopia, dysarthria, dysphonia, dysphagia), normal temp, clear sensorium - ingestion of canned food with toxin or wound contamination
54
Guillain-Barre
antecedant infection - ocular palsy, ASCENDING paralysis, parathesia
55
Tick Paralysis
ASCENDING paralysis - large muscles,
56
paralytic shellfish poisoning
parathesia digits hands/feet, loss of control arms/legs
57
Oral candidiasis with esophageal involvement
oral fluconazole - can't use just swish and swallow nystatin
58
DM associated osteomyelitis
Pseudomonas (foul smelling) - vanc/meropenum (MRSA/pseudomonas)
59
HIV in pregnancy
DON'T use efavirenz (teratogenic) - use zidovudine, lamivudine, lopinavir-rotinavir to prevent vertical transmission
60
Dengue Fever
mosquito bite - fever with chills, severe h/a, retroorbital pain, MSK pain, non specific rash sparing palms/soles - SE Asia, tropics, abn LFTs,
61
Leptospirosis
contact with animal urine or tissues (rodents/small mammals) - high fever, myalgia, abd pain
62
CA-MRSA soft tissue infxn
Bactrim,
63
TB Skin testing
>5mm - contact with active TB, HIV, old fibrosis on cxr, | >10mm - IVDA, from endemic countries, employee/resident NH, prison, mycobacterial lab workers, pt with r/o TB (DM, CKD)
64
Post Tx infection (kidney)
CMV - fever, cytopenia, hepatitis, low plt, seropositive donor EBV - would have LAD Poly BK Virus - decoy(inclusion cells) in urine