Deck 3: CENTRAL NERVOUS SYSTEM DRUGS

Question 1

Neuropharmacology

Answer 1

Is the study of substances that have the ability to change processes that are regulated by the neurological system.

Question 2

Axonal Conduction

Answer 2

The transmission of an action potential up the axon of a neuron, which is analogous to the transmission of real electricity to the body.

Question 3

Synaptic Transmission

Answer 3

The transfer of information from one neuron to the next at a postsynaptic cell is referred to as the synaptic process.

Question 4

Central Nervous System Drugs

Answer 4

Used for the treatment of mental disorders, the alleviation of pain, the induction of sedation, and the suppression of convulsions.

Question 5

Amphetamines

Answer 5

Stimulates the release of NE and DA from the brain and SNS.

Question 6

2 Major Types of Seizures

Answer 6

1. Partial Seizures
2. Generalized Seizures

Question 7

Anti-Epileptic Drugs Mechanism

Answer 7

• Suppression of sodium influx
• Suppression of calcium influx
• Antagonism of glutamate
• Potentation of GABA

Question 8

Hydantoins

Answer 8

Phenytoin - anticonvulsant drug

Question 9

Barbituarates

Answer 9

Phenobarbital - daytime sedative

Question 10

Iminostilbenes

Answer 10

Carbamazepine - epilepsy theraphy

Question 11

Benzodiazepines

Answer 11

1. Diazepam
2. Clonazepam
3. Clorazepate
4. Lorazepam

Question 12

IV Lorazepam

Answer 12

DOC for acute management of status epilepticus.

Question 13

Clonazepam

Answer 13

Treatment for absence, atypical absence seizures.

Question 14

Carboxylix Acid Derivatives

Answer 14

• Valproate
• Valproic Acid
• Divalproex
  – Suppression of neuronal firing

Question 15

Gabapentin

Answer 15

Increased levels of GABA in the brain are the consequence of molecules that bind to a carrier protein and then act on a receptor.

Question 16

Muscle Spam

Answer 16

Involuntary muscle or muscle group contraction that is painful and reduces function.

Question 17

Neuromuscular Blocking Drugs

Answer 17

Disrupt nerve signals at the neuromuscular junction to relax muscle contractions.

Question 18

Non-Depolarizing Blocking Drugs

Answer 18

Stabilizing drugs

Question 19

Non-Depolarizing Agents

Answer 19

• Ease of passage of an endotracheal tube
• Decrease the amount fo anesthetic required during surgery
• Facilitate realigning broken bones and dislocated joints
• Prevent muscle injury during ECT

Question 20

Depolarizing Blocking Drugs

Answer 20

Succinylcholine- acts like acetylcholine but not inactivated by ACHe.