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Question 1

• absence of melanocytes

* causes depigmentation

Answer 1

Vitiligo

Question 2

• associated with defects in collagen support structure of dermis

Answer 2

Ehlers-Danlos Syndrome

Question 3

• location: flexor surfaces in adults
• etiology: filaggrin mutation
• associated with asthma and allergic rhinitis
• staph aureus is suggested to exacerbate this disorder
• in children, is on cheecks and extensor surfaces
• eczema is type of atopic dermatitis

Answer 3

Atopic Dermatitis

Question 4

• type of atopic dermatitis

Answer 4

Eczema

Question 5

• etiology: common irritants

Answer 5

Irritant Contact Dermatitis

Question 6

• etiology: common allergens
• delayed type hypersensitiviey reaction (type 4)
• diagnosis confirmed with patch testing
• skin biopsy would reveal spongiotic dermatitis

Answer 6

Contact Dermatitis

Question 7

• location: lower legs

* etiology: lower extremity edema

Answer 7

Stasis Dermatitis

Question 8

• same as nummular eczema
• round, annular, scaly plaques
• due to dry skin
• overuse of soap can make this worse

Answer 8

Numular Dermatitis

Question 9

• location: scalp
• etiology: malassezia furfur
• also known as cradle cap
• infection of sebaceous glands

Answer 9

Seborrheic Dermatitis

Question 10

• location: extensor surfaces
• may include arthritis
• may be associated with increased cardiovascular risk

Answer 10

Chronic Plaque Psoriasis

Question 11

• skin cancer
• most common
• pearly
• common on nose
• tx: mohs surgery, vismoedgib (blocks smoothend gene)

Answer 11

Basal Cell

Question 12

• second most common skin cancer
• occurs more common in immunosupporessed pts keratoacanthoma is a type of this cancer
• center crater
• develop rapidly
• on sunexposed skin, HPV, thermal injury
• actinic keratosis is premalignant skin lesion

Answer 12

Squamous Cell

Question 13

• skin cancer

Answer 13

Melanoma

Question 14

• often associated with immunodeficiency

Answer 14

Kaposi Sarcome

Question 15

• can be treated with beta blockers
• most common benign soft tissue tumor of infants
• GLUT1 positive

Answer 15

Infantile Hemangioma

Question 16

• associated with high levels of GLUT-1 expression (a placenta associated marker)
• also called strawberry hemangioma

Answer 16

Infantile Hemangioma

Question 17

• associated with glaucoma and seizures

Answer 17

Port Wine Stain

Question 18

• linear plaque on the face or scalp
• yellow-orange
• associated with allopecia

Answer 18

Nevus Sebaceus

Question 19

• most commonly on face>trunk>extremity

* beign tumor of oil gland

Answer 19

Sebaceus Hyperplasia

Question 20

• from fibroblast
• firm papule
• most common on legs
• dimple sign is characteristic

Answer 20

Dermatofibroma

Question 21

• scar gowth above and beyond original border

Answer 21

Keloid Scar

Question 22

• sudden appearance associated with adenocarcinoma of the stomach

Answer 22

Seborrheic Karatosis

Question 23

• flat macules

* palms and soles most common

Answer 23

Junctional Nevus

Question 24

• more common in asians and causcasians

Answer 24

Blue Nevus

Question 25

* biggest risk factor for melanoma * familial atypical moles and melanoma criteria: The occurrence of malignant melanoma in 1 or more first- or second-degree relatives The presence of numerous (often >50) melanocytic nevi, some of which are clinically atypical Many of the associated nevi showing certain histologic features  CDK2NA mapped to 9p21  CDK4 mapped to 12q14   CMM1 mapped to 1p

Answer 25

FAMMM Syndrome

Question 26

* six or more cafe au lait spots * two or more neurofibromas * axillary or inguinal freckling (Crowe's sign) * first degree relative with disorder * autosomal dominant

Answer 26

Neurofibromatosis

Question 27

* multiple lesions associated with neurofibromatosis

Answer 27

Cafe au Lait Patch

Question 28

* melassezia furfur is causative agent

Answer 28

Tinea Versicolor

Question 29

* acquired disease involving antibodies to cell-to-cell adhesion molecules in the stratum spinosum (keratinocytes) * attacks desmosomes

Answer 29

Permphigus Vulgaris

Question 30

* vitamin cross links tropocollagen together * this disease is characterized by lack of vitamin C * SS: keratotic plugging of hairs, corkscrew hairs, hemorrhagic gingivitis

Answer 30

Scurvy

Question 31

* type 2 antibody mediated | * detachment between dermis and epidermis- hemidesomsomes

Answer 31

Bullous Pemphigoid

Question 32

* do not debride | * tx with steroids and immunosuppression

Answer 32

Pyoderma Gangrenosum

Question 33

* associated with hepatitis

Answer 33

Lichen Planus

Question 34

* with internal malignancies, pts tend to have weight loss- most common is stomach cancer * thickening of the skin * common causes: obesity, diabetes

Answer 34

Acanthosis Nigricans

Question 35

* filagrin mutation

Answer 35

Icthyosis Vulgaris

Question 36

* honey colored | * associated with strep and staph

Answer 36

Impetigo