DEFERRALS

Question 1

• History of parenteral drug use

Answer 1

PERMANENT DEFERRAL

Question 2

• Received clotting factor concentrate

Answer 2

PERMANENT DEFERRAL

Question 3

• High-risk occupation (i.e., prostitution)

Answer 3

PERMANENT DEFERRAL

Question 4

• Positive test for HBsAg

Answer 4

PERMANENT DEFERRAL

Question 5

• Positive Viral Hepatitis since 11 years of age

Answer 5

PERMANENT DEFERRAL

Question 6

• Presence of HCV, HTLV, HIV infection

Answer 6

PERMANENT DEFERRAL

Question 7

• Risk factors for Creutzfeldt-Jakob disease (prions) or who have an immediate family with CJD

Answer 7

PERMANENT DEFERRAL

Question 8

• Received human-derived growth hormonel corneal/ dura mater

Answer 8

PERMANENT DEFERRAL

Question 9

• Received a xenotransplantation

Answer 9

PERMANENT DEFERRAL

Question 10

• Received bovine insulin (Mad cow disease)

Answer 10

PERMANENT DEFERRAL

Question 11

• Used Tegison (treatment for psoriasis; considered teratogenic or may cause developmental or congenital malformation)

Answer 11

PERMANENT DEFERRAL

Question 12

• Autoimmune disease

Answer 12

PERMANENT DEFERRAL

Question 13

• Men-to-men sexual contact since 1977

Answer 13

INDEFINITE DEFERRAL

Question 14

• Men & women engaged in sex for money/drug since 1977

Answer 14

INDEFINITE DEFERRAL

Question 15

• CJD or vCJD-related deferrals

Answer 15

INDEFINITE DEFERRAL

Question 16

Blood relative of someone diagnosed with CJD or vCJD

Answer 16

INDEFINITE DEFERRAL

Question 17

Who spent 3 months in UK from 1980 through 1996

Answer 17

INDEFINITE DEFERRAL

Question 18

Spent 5 years in Europe from 1980 to the present

Spent 5 years or more in France from 1980 to the present

Answer 18

INDEFINITE DEFERRAL

Question 19

For persons who served in the U.S. military, who spent 6 months or more in Northern Europe (Germany, UK, Belgium, the Netherlands) from 1980 to 1990 or spent 6 months or more from 1980 to 1996 in Greece, Turkey, Spain, Portugal, or Italy.

Answer 19

INDEFINITE DEFERRAL

Question 20

If a donor received a blood transfusion in the United Kingdom from 1980 to the present

Answer 20

INDEFINITE DEFERRAL

Question 21

If a donor received bovine insulin since 1980 unless the bovine insulin did not come from the United Kingdom

Answer 21

INDEFINITE DEFERRAL

Question 22

Those who have received a transfusion of blood, platelets, plasma, cryoprecipitate, or granulocytes in the United Kingdom or France since 1980.

Answer 22

INDEFINITE DEFERRAL

Question 23

CJD

Answer 23

Creutzfeldt-Jakob Disease

Question 24

Have Leukemia/Lymphoma or other types of Cancer

Answer 24

INDEFINITE DEFERRAL

Question 25

Diseases of the blood such as • hemophilia, • von Willebrand disease, • sickle cell anemia, • thalassemia, • Kaposi's sarcoma, • polycythemia, or a history of receiving clotting factor concentrates

Answer 25

INDEFINITE DEFERRAL

Question 26

Anyone who was born or lived in any of the African countries on the FDA list of countries with HIV-1 group 0 risk since 1977

Answer 26

INDEFINITE DEFERRAL

Question 27

Sexual contact with anyone who was born or has lived in Africa

Answer 27

INDEFINITE DEFERRAL

Question 28

Current List of Countries with HIV-1 Group O Risk

Answer 28

Benin Cameroon Central African Republic Chad Congo Equatorial Guinea Gabon Kenya Niger Senegal Togo Zambia

Question 29

• Contains killed pathogens • NO risk of disease transmission • Donor can usually donate immediately or after 24–48 hours if feeling well.

Answer 29

Inactivated Vaccine

Question 30

Influenza, Hepatitis A, Tdap, COVID-19 [Pfizer/Moderna]

Answer 30

Inactivated Vaccine

Question 31

• Contains weakened live organisms • There is a small risk of viral shedding • Donor is usually deferred for 2–4 weeks, depending on the specific vaccine.

Answer 31

Live-Attenuated Vaccine

Question 32

e.g., MMR, Varicella, Yellow Fever, BCG, Intranasal Flu

Answer 32

Live-Attenuated Vaccine

Question 33

• Uses a harmless virus to deliver a genetic code to the body • If non-replicating, donors are usually eligible after 48 hours • If replication-competent, deferral period may be longer, usually around 2–4 weeks

Answer 33

Viral Vector Vaccine

Question 34

e.g., AstraZeneca, Johnson & Johnson COVID-19 vaccines

Answer 34

Viral Vector Vaccine