Definitions Flashcards
(33 cards)
Epigenetics
Preference changes in the expression of genes that are already present, that bring about change in a bahaviour
Broad sense heritability
Proportion of variance in phenotype due to genetic variation
H2 = (VG/(VG+VE)
Broad sense heritability (VG= Genotype variance, VE= Environmental variance)
Narrow sense heritability
Proportion of total phenotypic variation that is due to the additive effects of genes
H2 = (VA/(VA+VE)
narrow sense heritability
Central DOGMA
The genetic flow of information from DNA, to mRNA, to proteins.
Genome
Entirety of an organism’s hereditary information
Exon
Coding region of a gene
Intron
Region of a gene that is not translated into proteins
Intergenic regions
“junk DNA” between genes; some regulatory functions
1) Replication
1st stage of protein synthesis: where DNA replicates into 2 identical copies
2) Transcription
2nd stage of protein synthesis: Making a complementary RNA copy of a DNA sequence (U replaces T)
3) Translation
3rd stage of protein synthesis: amino acid chain created from mRNA
2a) Splicing
Removes introns and joins exons during protein synthesis
Horizontal memory
Cells made for your own body
Vertical momory
Cells inter-generationally transferred
Chromatin
complex form of DNA and protein in eukaryotes
Histones
Major proteins, highly alkaline
Euchromatin
lightly packed form of DNA
Heterochromatin
tightly packed form of DNA; repetitive with few coding regions
Genomic Imprinting
Silencing of one parental copy of DNA
X-Silencing
Turning off expression of 1 X-Chromosome to prevent double quantities
Catch-Up Growth
Poor childhood growth and then a better boom can worsen condition
The 1992 Thrifty Phenotype Hypothesis
Cutting corners allow offspring to survive there and then; right here right now approach