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Neuro > Degenerative Neuro Disorders > Flashcards

Degenerative Neuro Disorders Flashcards

0
Q

parkinson’s is an imbalance between which 2 neurotransmitters

A

dopamine

acetylcholine

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1
Q

a chronic progressive degenerative disease of the brain’s dopamine system

A

Parkinson’s disease

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2
Q

what is the cause of parkinson’s

A

unknown

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3
Q

what is the cause of secondary Parkinson’s

A

trauma

drugs

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4
Q

what is an early sign of tremor in a parkinson’s pt

A

handwriting disturbance

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5
Q 
what has these s/s:
tremor
rigidity
bradykinesia
posture instability
A

parkinson’s

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6
Q

which drug is a precursor to dopamine

A

levodopa

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7
Q

which drug is the “gold standard” in parkinson’s tx

A

levodopa

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8
Q

which type of drug blocks the synthesis of dopamine

A

MAO-B inhibitors

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9
Q

which type of drug:
selegiline
rasagiline

A

MAO-B inhibitors

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10
Q

which type of drug blocks acetylcholine receptors

A

anticholinergics

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11
Q

which type of drug controls tremors & rigidity

A

anticholinergics

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12
Q

which type of drug has these s/e:
urinary retention
dry mouth
⬇️ GI motility

A

anticholinergics

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13
Q

which type of drug:
artane
cogentin

A

anticholinergics

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14
Q

which type of drug:
symmetral
amantadine

A

dopamine agonist

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15
Q

which drug ⬆️ levodopa levels in the brain

A

COMT inhibitors

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16
Q

which type of drug can develop tolerance

A

COMT inhibitors

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17
Q

which type of drug may cause tardive dyskinesia

A

COMT inhibitors

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18
Q

which type of parkinson’s drug should be taken prior to meals

A

COMT inhibitors

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19
Q

which type of drug:
entacapone
tolcapone

A

COMT inhibitors

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20
Q

what is a surgery that interrupts nerve pathways to alleviate tremors & rigidity

A

ablation surgery

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21
Q

which condition is deep brain stimulation used with

A

parkinson’s

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22
Q

an autoimmune disease affecting the brain & spinal cord; myelin is lost/destroyed

A

MS

23
Q

condition that disrupts the ability of nerves to conduct electrical impulses to & from the brain

A

MS

24
Q

type of MS:

acute attacks w/ recovery; most common

A

RRMS

relapsing-remitting

25
Q

type of MS:

progressive disability/constant worsening

A

PPMS

primary progressive

26
Q

type of MS:

begins as RR followed by variable progression

A

SPMS

secondary progressive

27
Q

type of MS:

relapse but w/o recovery; gets very bad

A

PRMS

progressive relapsing

28
Q

which 2 tests are used to diagnose MS

A

lumbar puncture

MRI

29
Q

what is the most common MS symptom

A

fatigue

30
Q 
what has these s/s:
paresthesia
memory loss
depression
gait/coordination problems
fatigue
A

MS

31
Q

which MS drug is given IM every week

A

avonex

32
Q

which MS drug is given SQ every other day

A

Betaseron

33
Q

which MS drug is given SQ every day

A

Copaxone

34
Q

which MS drug is given SQ 3x/week

A

Rebif

35
Q

which MS drug is given to treat spasticity

A

baclofen

36
Q

which MS drug is given to treat pain

A

amitriptyline

37
Q

which MS drug is given to treat depression/fatigue

A

wellbutrin

38
Q

which MS drug is given to treat bladder dysfunction

A

ditropan

39
Q

an autoimmune disease that destroyes acetylcholine receptors at the neuromuscular junction

A

myasthenia gravis

40
Q

what are the 2 initial symptoms of myasthenia gravis

A

ptosis

diploplia

41
Q

what is a progressive symptom of myasthenia gravis

A

muscle weakness

42
Q

what is the diagnostic test for myasthenia gravis

A

tensilon test

43
Q

which test injects acetylcholinesterase to see if s/s improve temporarily

A

tensilon test

44
Q

what is the name of the blood marker test for myasthenia gravis

A

immunoassay

45
Q

which type of myasthenia gravis drug:
mestinon
prostigman

A

anticholinesterase

46
Q

which myasthenia gravis drug is given to inhibit T lymphocytes

A

imuran

47
Q

what is a surgical treatment of myasthenia gravis

A

thymectomy

48
Q

what is a myasthenic crisis caused by

A

infection

undermedication

49
Q

what is a cholinergic crisis caused by

A

overmedication

50
Q

s/s of this crisis:
dysphagia
dysarthria
ptosis

A

myasthenic crisis

51
Q 
s/s of this crisis:
abdominal cramps
N/V/D
⬆️ salivation
bradycardia
A

cholinergic crisis

52
Q

degeneration of spinal cord/nerve endings; progressive descending muscle weakness

A

ALS/Lou Gehrig’s disease

53
Q

what is the first symptom of ALS

A

cramping of one lower extremity

54
Q

what are the upper motor neuron symptoms of ALS

A

dysphagia

dysphonia

55
Q

what are the lower motor neuron symptoms of ALS

A

weakness
muscular atrophy
hyporeflexia

56
Q

which med is given to slow motor neuron destruction with ALS

A

Rulitek

Neuro (7 decks)

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