Delirium Flashcards

1
Q

What are the key features of delirium?

A
  • Disturbed consciousness (essential for delirium diagnosis)- can be hypoactive/hyperactive or a mix of both
  • Change in cognition
  • Acute onset and fluctuant
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2
Q

What are other common, but not key, features of delirium?

A
  • Disturbance of sleep wake cycle
  • Disturbed psychomotor behaviour
  • Emotional disturbance
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3
Q

When is delirium most common?

A

At the extremes of age

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4
Q

Name some factors that can precipitate delirium

A
  • Infection (but not always a UTI!)
  • Dehydration
  • Biochemical disturbance
  • Pain
  • Drugs
  • Constipation/Urinary retention
  • Hypoxia
  • Alcohol/drug withdrawal
  • Sleep disturbance
  • Brain injury (stroke/tumour/bleed etc)
  • Changes in environment/emotional distress
  • Sometimes no idea and often multiple triggers
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5
Q

What percentage of patients are affected by delirium?

A

20-30% of in-patients
50% of people post-operatively
85% of patients at the end of life

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6
Q

What are the possible complications of delirium?

A
  • Increased morbidity and mortality
  • Longer length of stay in hospital
  • Increased rate of institutionalisation
  • Persistent functional decline
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7
Q

How is delirium diagnosed?

A

Using the 4AT screening tool

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8
Q

What are the component parts of the 4AT screening tool?

A

Alertness
AMT4
Attention
Acute change or fluctuating course

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9
Q

How is alertness assessed on a 4AT?

A

Ask patient to state name and address
If normal, 0 points
If sleepy <10s after waking, 0 points
If clearly abnormal, 4 points

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10
Q

How is AMT4 assess on a 4AT?

A

Ask the patient their location, age, their date of birth and the current year
No mistakes- 0 points
1 mistake- 1 point
2 or more mistakes- 2 points

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11
Q

How is attention assessed on a 4AT?

A

Ask patient to state months of the year in reverse order
Achieves 7 or more months correctly- 0 points
Starts but achieves <7 months/refuses to start- 1 point
Untestable- 2 points

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12
Q

How is acute change assessed on a 4AT?

A

Establish whether there is evidence of fluctuation or change in mental function over the previous fortnight that is still present in the last 24 hours
No- 0 points
Yes- 4 points

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13
Q

How is a 4AT score interpreted?

A

4 or above- possible delirium +/- cognitive impairment
1-3- possible cognitive impairment
0- delirium or cognitive impairment unlikely

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14
Q

What initial steps should be taken when delirium is diagnosed?

A

Full history and examination to establish the cause
Care should also be taking when giving the diagnosis to distinguish delirium from dementia and highlight that delirium usually settles down
Blood tests and ECGs can also be done to establish a cause

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15
Q

What is the non-pharmacological management of delirium?

A
  • Re-orientate/reassure agitated patients (family/carers usually better at this)
  • Encourage early mobility and self-care
  • Correction of sensory impairment
  • Normalise sleep-wake cycle
  • Ensure continuity of care
  • Avoid urinary catheters/venflons
  • Try and avoid admissions and discharge ASAP
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16
Q

What is the focus of pharmacological management of delirium?

A

Stopping bad drugs

17
Q

When should drug treatment of delirium be considered?

A

Drug treatment is only given when the patient is a danger to themselves or others or distressed and this cannot be settled in any other way

18
Q

What drug treatment is given for delirium?

A

12.5mg oral quetiapine

19
Q

What percentage of cases of delirium are preventable?

A

30%

20
Q

What steps can be taken to reduce the risk of delirium?

A
  • Orientation and ensuring patients have correct sensory aids
  • Promoting sleep hygiene
  • Early mobilisation
  • Pain control
  • Management of postoperative complications
  • Maintaining hydration and nutrition
  • Regulation of bowel and bladder function
  • Provision of oxygen if necessary
  • Medication review in patients at risk of delirium
21
Q

What is the prognosis for someone following an episode of delirium?

A

Usually returns to normal
Is a marker of physical and cognitive frailty
More likely to develop dementia, further delirium or any other frailty syndrome

22
Q

Why should care be taken when diagnosing UTI in the elderly?

A

Asymptomatic bacteriuria present in many institutionalised elderly people
Urine dipsticks not diagnostic in elderly
Overdiagnosis can cause missing true cause of delirium
Unnecessary antibiotic prescription will cause harm in 1/3 of elderly patients