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Introduction To Fungi - Hepatitis > Dengue Virus > Flashcards

Dengue Virus Flashcards

1
Q

is a viral infection
transmitted to humans
through the bite of
infected mosquitoes?

A

Dengue

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2
Q

A single positive-stranded RNA virus of the family
Flaviviridae; genus Flavivirus?

A

Dengue Virus

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3
Q

Family of Dengue Virus?

A

Flaviviridae

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4
Q

4 serotypes of Dengue?

A

DENV-1
DENV-2
DENV-3
DENV-4

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5
Q

The primary vectors that transmit the disease are?

A

Aedes aegypti

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6
Q

Life stages of mosquito?

A

Adult
Eggs
Larva
Pupa

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7
Q

The Aedes mosquitoes breed in forested areas using tree holes as its
natural habitat, but nowadays it has well adapted to urban habitats
and breeds mostly in ______ including buckets, mud
pots, discarded containers and used tires, storm water drains etc.,
thus making dengue an insidious disease in densely populated urban
centers.

A

man-made containers

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8
Q

Phases of dengue infection?

A

Febrile Phase
Critical Phase
Recovery Phase

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9
Q

Fever usually lasts 2-7 days.
➢ Other signs and symptoms may include severe headache; retro-orbital eye
pain; muscle, joint, and bone pain; macular or maculopapular rash; and
minor hemorrhagic manifestations including nosebleed/epistaxis, bleeding
gums, or a positive tourniquet test result?

A

Febrile Phase

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10
Q

Phase when patient can either improve or deteriorate?

A

Critical Phase

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11
Q

Occurs between 3 to 7 days of illness?

A

Defervescence

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12
Q

is known as the period in which the body temperature (fever) drops
to almost normal (between 37.5 to 38°C)?

A

Defervescence

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13
Q

Those who will improve after defervescence will be ?categorized as

A

Dengue without Warning Signs

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14
Q

While those who will deteriorate will
manifest warning signs and will be categorized as?

A

Dengue with
Warning Signs

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15
Q

As plasma leakage subsides and hemodynamic status stabilizes,
patients’ general well-being improves?

A

Recovery Phase

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16
Q

Laboratory Tests fo Dengue?

A
  1. Dengue NS1 RDT
  2. Dengue IgM/IgG
  3. PCR
  4. NAAT-LAMP
  5. PRNT
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17
Q

Requested between 1-5
days of illness. After day 7,
NS1 test is not
recommended?

A

Dengue NS1 RDT

18
Q

Requested beyond five days of
illness?

A

Dengue IgM/IgG

19
Q

One of the gold standard
laboratory tests to confirm
dengue virus?

A

PCR

20
Q

A novel molecular-based
confirmatory test used to detect
dengue virus?

A

NAAT - LAMP

21
Q

Gold standard to characterize
and quantify circulating level of
anti-DENV neutralizing antibody
(NAb)?

A

PRNT

22
Q

Other tests: routinely used in hospitals standard dengue diagnostic test?

A

-Total WBC Count
- Platelet
-Hematocrit

23
Q

decreasing WBC?

A

Leukopenia

24
Q

Decreasing platelet?

A

Thrombocytopenia

25
Q

Dengue symptoms usually last for?

A

2-7 Days

26
Q

Incubation period of dengue?

A

4-10 Days

27
Q

Dengue illness is categorized according to level of severity:

A
  1. Dengue without warning signs
  2. Dengue with warning signs
  3. Severe dengue
28
Q

A previously well individual
with acute febrile illness of 1-
7 days duration plus two of
the following: headache, body
malaise, retro-orbital pain,
myalgia, arthralgia, anorexia,
nausea, vomiting, diarrhea,
flushed skin, rash (petechial,
Hermann’s sign)?

A

Suspect dengue

29
Q

A suspect dengue case plus
laboratory test: Dengue NS1
antigen test and at least CBC
(leukopenia with or without
thrombocytopenia) or dengue
IgM antibody test (optional)?

A

Probable Dengue

30
Q

A suspect or probable
dengue case with positive
result of viral culture and/or
Polymerase Chain Reaction
(PCR) and/or Nucleic Acid
Amplification Test- Loop
Mediated Amplification Assay
(NAAT-LAMP) and/ or Plaque
Reduction Neutralization Test
(PRNT)?

A

Confirmed dengue

31
Q

Q previously well person
with acute febrile illness of 1-
7 days plus any of the
following: abdominial pain or
tenderness, persistent
vomiting, clinical signs of fluid
accumulation (ascites),
mucosal bleeding, lethargy or
restlessness, liver
enlargement, increase in
haematocrit and/or
decreasing platelet count?

A

Dengue with warning signs

32
Q

Severe bleeding and plasma leakage leading
to
shock (DSS)-hypotension, weak pulse
fluid accumulation with respiratory distress?

A

Severe Dengue

33
Q

Patients who may be sent home?

A

Group A

34
Q

Patient who should be referred for in hospital management?

A

Group B

35
Q

Patient with severe dengue requiring emergency treatment and urgent referral?

A

Group C

36
Q

Greeting the severity of thingy infection? Fever with two or more of the following: headache, retro-orbital pain, myalagia, arthralgia?

A

Grade 0

37
Q

Grading disability of dengue infection with positive tourniquet test?

A

Grade I

38
Q

Grading the severity of dengue infection with a spontaneous bleeding?

A

Grade II

39
Q

Grading the severity of thinking infection with circulatory failure?

A

Grade III

40
Q

Grading the severity of dengue infection with profound shock with undetectable blood pressure and pulse?

A

Grade IV

Introduction To Fungi - Hepatitis (8 decks)

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