Dental Anomalies Flashcards
(25 cards)
gene (codes a transcription fx) for missing maxillary PMs and mand 2nd PMs
Mxs1 (Mix)
Mxs1 codes a
transcription factor
Mxs1 mutation clinical significance
missing maxillary premolars and mandibular 2nd premolars
gene (codes transcription fx) that causes you to miss all molars
Pax9 (pass out)
Pax9 codes a…
transcription factor
I’m missing all my molars!
Pax9
Pax9 mutation clinical significance
missing molars
genes (codes signaling molecule) through Wnt pathway that causes you to be missing more than 8 permanent teeth
Axin2
Axin 2 codes a…
signalling molecule for the Wnt pathway
which pathway is the Axin 2 signaling molecule involved with?
Wnt pathway
Wnt pathway uses the _______ signalling molecul
Axin 2
a gene (codes a signaling molecule) that is involved in the TNF pathway
EDA
EDA codes for a…
signalling molecule for the TNF pathway
which gene codes for a signaling molecule involved in the TNF pathway?
EDA
Which pathways are the p63 gene’s transcription factor used in?
BMP, FSF, SHH
p62 codes a…
transcription factor (BMP, FGF, SHH pathways)
Which gene mutations are related to missing teeth?
Mxs1, TF Pax9, TF p63, TF (BMP, FGF, SHH paths) Axin2, SM (Wnt path; colon cancer) EDA, SM (TNF path)
which gene codes for a signaling molecule that is related to missing more than 8 permanent teeth and risk of colon cancer?
Axin 2
Which gene mutation are related to supernumerary teeth?
Runx2 (TF) ; cleidocranial dysplasia
Apc (SM) ; Wnt pathway ; Gardner’s Syndrome (w/ GI problems)
Runx2 disorder
cleidocranial dysplasia
Apc disorder
Gardner’s Syndrome
Runx2 is a…
transcription factor
Apc is a…
signaling molecule ; Gardner’s syndrome
missing multiple anterior teeth
EDA gene mutation for the signaling molecule of the TNF pathway
