Depression Flashcards

(35 cards)

1
Q

What are the three defining criteria for depression, for which you must have at least 2/3?
(according to ICD-10 section A)

A

Persistent low mood
Loss of interest / pleasure
Fatigue or low energy

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2
Q

Define Anhedonia

A

Loss of enjoyment

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3
Q

Minor criteria for Depression (section B)

A
Suicidal thoughts
Disturbed sleep
Diminished appetite 
Reduced concentration
Reduced confidence/self esteem
Ideas of guilt and worthlessness
Hopelessness for future
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4
Q

ICD-10 Criteria for Minor depression

A

A - 2/3

B - 2

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5
Q

ICD-10 Criteria for moderate depression

A

2/3 from A

3+ from B

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6
Q

ICD-10 Criteria for severe depression

A

3/3 from A

4+ from B

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7
Q

In depression, low mood tends to be diurnal, true or false?

A

True

Tends to be worst in the morning

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8
Q

Define Dysthymia

A

Longstanding mild depressive symptoms, often associated with other psychiatric or physical illness.

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9
Q

Define Atypical Depression

A

Patient depressive symptoms include excess sleep, increased appetite and phobic anxiety.

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10
Q

What class of drugs do atypical depression patients respond well to?

A

Monoamine Oxidase Inhibitors

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11
Q

Depression occurs more in men? true/false

A

False
Ratio of depression is 1:2
M:F

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12
Q

List some defining features of the appearance of a patient with depression?

A
Furrowed brow
Reduced eye contact
Reduced facial expressions
Minimal/limited gesturing
Difficult to build rapport
Potentially dishevelled and unkempt
Appearance of not sleeping
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13
Q

List some defining features of speech in a patient suffering from depression

A
Reduced rate
Lowered volume
Reduced intonation
Lowered pitch
Minimal content
Increased speech latencies
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14
Q

In depression, a patient’s insight tends to be impaired. True/False?

A

False

Patients suffering from depression tend to retain insight

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15
Q

What is somatic syndrome?

A

When a patient experiences at least 4/6 of the following:

  • Loss of libido
  • weight loss
  • loss o appetite
  • Diurnal variation
  • Early wakening
  • Psychomotor retardation
  • Marked loss of interest
  • Lack of emotional reactions
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16
Q

Define a depressive stupor:

A

When psychomotor retardation leads to the patient being motionless and mute
Can be fatal if patient suffers from dehydration
ECT is choice of treatment

17
Q

Define Cotard’s Syndrome:

A

Patient with psychotic depression thinks that a part of their body is dead

18
Q

Biological Factors which contribute to Depressive disorder

A
  • Genes
  • Medical conditions (organic disorders)
  • Altered HPA axis function
  • Monoamine Abnormalities
  • Chronic Health conditions
19
Q

Psychological factors which contribute to Depressive Disorders

A

Childhood environment
Emotional deprivation / parental loss
Abnormal cognition
Personalist factors e.g. neuroticism

20
Q

Social Factors which can contribute to Depressive Disorders

A
Isolation
Unemployment
Abuse
Bereavement
Relationship problems
Drug misuse / addictions
21
Q

What is normally first line pharmacological treatment for depression?

A

SSRI’s

e.g. fluoxetine

22
Q

What must you monitor for when prescribing SSRI’s to patients <25 y/o?

A

Suicidal thoughts

SSRI’s are known to increase suicidal tendencies in patients, especially under 25 y/o

23
Q

How long must you continue anti-depressant treatment once episode has been resolved?

A

6 months to a year

24
Q

What factors can contribute to your management plan for depression?

A

Previous treatments and response to them?
Family history of depression/use of anti-depressants
Patient’s preference
Suicide risk in patient - some are more toxic
Sedative effects - required or not

25
Up to 2/3rds of patients do not respond to initial treatment? True/False
True | 2/3rds of patients do not respond to first line treatment in depression
26
What things can be done to improve response to treatment?
``` Increase dose Add adjunctive therapy Change class of drugs Check patient compliance Check timeline - most drugs take at least 6 weeks to become effective ```
27
What other therapies are available, besides pharmacological, for depression?
CBT Talking therapy Counselling ECT
28
What % of patients who suffer from depression will relapse?
>50%
29
Risk of suicide is increased in patients with depression. True/False
True | Risk increase 10x
30
What is the mean age of onset of depression?
20's
31
Define psychomotor retardation?
When there is a subjective or objective slowing of thoughts
32
What counts as "early morning wakening"?
When the patient wakes at least 2 hours earlier than their normal and does not return to sleep
33
Define Psychotic Depression
Depression associated with occasional paranoia's e.g. cotards syndrome
34
List some physical (organic) diseases which can induce depression-like symptoms:
``` Hypothyroidism Hypoglycaemia Steroid Treatment Brain Tumour Cushing's disease ```
35
List some physical symptoms which can be manifestations of depressive disorders?
``` Headache Fatigue Loss of appetite Weight loss constipation Loss of libido Insomnia Muscle aches/pains ```