Derm Flashcards
(23 cards)
1st line management of acne?
Topical combination therapy (topical retinoid, benzyl P)
(topical adapalene with Benzyl P)
(topical retinoid with topical clinda)
(topical clinda with topical benzyl P)
NOTE: ADAPALENE is a topical retinoid
TOPICAL Benzyl P can be used first line as montotherapy if people wish to avoid ABx / retinoid
What ABx for acne in pregnancy?
Erythromycin
What is a known complication of long term ABx in acne and Rx?
Gram -ve folliculitis.
Use high dose trimethoprim
Mild acne definition?
Open and closed comedones with or without sparse inflammatory lesions
Moderate acne definition?
Widespread, numerous pustules and papules
Severe acne definition?
Extensive inflam lesions with nodules, pitting and scarring
Acne rosacea 1st line Rx?
Topical ivermicten (alternative include metronidazole or azeleic acid)
What can be used for flushing in acne rosacea?
Topical brimonidine (topical alpha adrenergic agonist)
Use moderate to severe papule or pustules in rosacea ?
Topical ivermicten and oral doxycycline
Management of eczema herpeticum and cause?
HSV 1 / HSV 2
Rapidly progressing painful rash in people with eczema
Admit for IV aciclovir
HLA associations of psoriasis?
B13 / B17
What causes guttate psoriasis?
Strep infection.
2-4 weeks prior
‘Tear drop scaly papules’ Usually self resolve
1st line Rx of psoriasis
Potent steroid and Vit D analogue (calcipotriol). (OD one in am, one in PM)
For up to 4 weeks
2nd line treatment of psoriasis (if no response after 8 weeks)
Vitamin D analogue BD
3rd line Rx psoriasis?
Potent steroid BD for 4/52 or coal tar daily
Management of psoriasis in secondary care?
Methotrexate 1st line.
Also Narroband UVB, PUVA (RISK OF SCC)
Management of scalp psoriasis
NICE recommend potent steroid for 4 weeks
NOTE: NICE recommend a 4 week break between steroid courses.
Face, flexural or genital psosirais ?
Mild/mod steroid for 2/52
Duration of use of steroids as per nice:
Can use potent up to 8 weeks
Very potent up to 4 weeks
Hydro. (mild)
Eumovate (mod)
Betnovate (pot)
Dermovate (v. pot)
How do Vit D analogues work in psoriasis?
they work by ↓ cell division and differentiation → ↓ epidermal proliferation
Nail signs in psoriasis?
Pitting, Onycholysis (when nail separates from nail bed). Loss of mail. Keratosis