Derm 7 Flashcards
(39 cards)
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What does AMS stand for?
Antimicrobial Stewardship.
What is the NICE definition of AMS?
An organisational approach to promote and monitor judicious antimicrobial use to preserve their effectiveness.
What is the BSAC definition of AMS?
The optimal selection, dosage, and duration of antimicrobials for best clinical outcome with minimal toxicity and resistance.
What are the core goals of AMS?
Improve patient outcomes, improve safety (reduce Clostridium difficile), reduce resistance, reduce healthcare costs.
What is the role of primary care in the NHS?
First point of patient contact; provides 80% of all NHS antibiotic prescribing.
What are Integrated Care Boards (ICBs)?
NHS organisations responsible for health service delivery, budget, and antimicrobial guidelines in local areas.
What is the TARGET antibiotics toolkit?
Stands for Treat Antibiotics Responsibly, Guidance, Education and Tools; supports AMS in primary care.
What roles do community pharmacists have in AMS?
Screen prescriptions, advise on self-care, support public health campaigns, diagnose and treat minor infections under PGD.
What roles do clinical pharmacists in GP surgeries have?
Diagnose infections, advise on prescribing, maintain patient records, conduct audits, review antimicrobial prescriptions.
What roles do pharmacists in care homes have?
Early infection detection, antimicrobial review, conduct audits, structured medication reviews.
What roles do pharmacists in ICBs have?
Implement AMS across local healthcare, create local guidelines, conduct audits, train staff, monitor prescribing trends.
What is acne and who does it affect?
A multifactorial skin disease affecting 30–70% of adolescents, mainly on face, back, and chest.
What are the four main events leading to acne?
Excessive sebum production, abnormal keratinisation, Cutibacterium acnes proliferation, inflammation.
How is mild acne characterised?
Mostly open/closed comedones and few papules or pustules, usually facial.
How is moderate acne characterised?
More widespread papules and pustules, may include mild scarring.
How is severe acne characterised?
Widespread lesions including cysts and abscesses, often with severe scarring.
What is the first-line NICE treatment for acne?
12-week topical combination of adapalene with benzoyl peroxide (non-antibiotic).
What topical treatment can be used for any acne severity?
Combination of tretinoin with clindamycin (antibiotic).
What combination is used for mild-to-moderate acne?
Topical benzoyl peroxide with clindamycin.
What is used for moderate-to-severe acne?
Topical adapalene + benzoyl peroxide + oral lymecycline or doxycycline.
What is an alternative for moderate-to-severe acne?
Topical azelaic acid + oral lymecycline or doxycycline.
Why avoid combined topical + oral antibiotics?
To prevent antimicrobial resistance.
What is the mode of action of benzoyl peroxide?
Releases free oxygen radicals for bactericidal activity; reduces follicular hyperkeratosis.