Derm Formative Week 1 Flashcards
(18 cards)
Component of MRSA which causes necrotising fasciitis
PVL
Blisters on dorsal aspect of hands, fragile skin, hypertrichosis of the malar region
Porphyria cutanea tarda
Anagen
Catagen
Telogen
Which phases ?
Anagen = Growing phase
Catagen = Involuting phase
Telogen = Resting phase
Where are Langerhans cells produced ?
Bone marrow
Bulla
Papule
Plaque
Pustule
Nodule
Wheal
Vesicle
Macule
During foetal development, which skin layer is most metabolically active ?
Basal layer
Which cells carry out Vitamin D metabolism ?
Keratinocytes
Acute intermittent porphyria = deficiency of which enzyme ?
Porphobilinogen deaminase
(causing an accumulation of porphobilinogen)
Which cells produce collagen ?
Fibroblasts
A= Keratin layer
B=
C = Melanocytes
D = sebaceous gland
E =
F = epidermis and dermis,
G = fibroblasts
H = sebaceous gland
I = Arrector pili muscle
J = Papilla and matrix of hair follicle
Type I hypersensitivity =
Immediate hypersensitivity
Type II hypersensitivity
Direct cell killing
A is the keratin layer.
B is the granular layer.
C is the prickle cell layer.
D is the basal layer.
E is the dermo-epidermal junction,
F is the dermis
Hypersensitivity:
Mediators of :
Type I
Types II and III
Type IV
Type I = IgE
Types I and II = IgG, IgM
Type IV = Th1
Crust
Fissure
Erosions
Maceration
Ulcer
Lichenification
Scale
Atrophy
What provides pressure and vibration sensations respectively ?
Pacinian corpuscles, Meissner’s corpuscles
Erythropoeitic protoporphyria enzyme
Ferrochelatase
Lip and tongue swelling 5 minutes after eating a prawn sandwich. What type of hypersensitivity reaction ?
And what is the mediator ?
Type I immediate hypersensitivity
Mediated by IgE
