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Derm Pharm Crossword Flashcards

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1
Q

oral hedgehog pathway inhibitor that can be used for advanced basal cell carcinoma

A

vismodegib

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2
Q

tetracycline used to treat acne

A

minocycline

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3
Q

prescription synthetic topical antimycotic agent with broad spectrum of activity

A

ciclopirox

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4
Q

aminoglycoside antibiotic of Neosporin with activity against gram-negative bacteria

A

neomycin

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5
Q

topical treatment for lesions due to herpes simplex

A

acyclovir

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6
Q

important component of wound healing

A

debridement

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7
Q

class of antifungal drugs with a wide range of activity

A

imidazoles

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8
Q

unless wounds appear clinically infected

A

antibiotics

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9
Q

blocks the conversion of testosterone to more potent androgen dihydrotestosterone

A

finasteride

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10
Q

K+-sparing diuretic with partial agonist properties at androgen receptors that can make it useful for treating menstrual cycle-linked acne or male pattern baldness in adult women

A

spironolactone

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11
Q

low-pressure implementation of this with normal saline is an important component of healing

A

irrigation

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12
Q

control that is now considered a priority for optimal wound closure

A

glycemic

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13
Q

MAP kinase pathway inhibitor useful for melanoma BRAF V600E mutation

A

vemurafenib

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14
Q

route of administration where pharmacokinetic factors influencing absorption and distribution of drug include region

A

cutaneous

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15
Q

broad-spectrum antimicrobial agent widely used in homes and hospitals due to efficacy on skin and oral mucosa with low irritability

A

chlorhexidine

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16
Q

very old remedy for psoriasis; works but color and smell create a challenge

A

tar

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17
Q

agents such as iodine

A

impede

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18
Q

component of plant defenses against bacteria

A

azeleic acid

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19
Q

class of adrenergic agonists administered topically to treat rosacea or red eyes; oxymetazoline and tetrahydrozyline are among the examples

A

alpha

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20
Q

topical antimicrobial agent commonly used to treat acne; local skin irritant and may bleach hair or clothing

A

benzoyl peroxide

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21
Q

treated surgically when possible with 1-2 cm margins and conventional chemotherapy based on dacarbazine

A

melanoma

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22
Q

drug class that may or may not stop the itch

A

antihistamines

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23
Q

can be an effective treatment for acne in women

A

combination oral contraceptives

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24
Q

among the wound coverings preferred during the granulation and epithelialization phases of wound healing

A

low adherence

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25
radiation that may not cause erythema and sunburn but still does contribute to skin aging and photocarcinogenesis; under strict supervision
UVA
26
chemotherapeutic agent useful for melanoma
dacarbazine
27
region where highest potency glucocorticoids should not be used
face
28
late choice for treating ectoparasites
lindane
29
applied to skin to kill microbes
antiseptic
30
when used to treat thrush
nystatin
31
treatment for actinic keratoses derived from Euphorbia peplus sap
ingenolmebutate
32
organophosphate anticholinesterase insecticide
malathion
33
refers to autoantibody mediated hair loss that is treated with corticosteroids and/or an agent such as DPCP to induce a contact dermatitis with typical hair growth restoration in the healed skin
alopecia areata
34
local anesthetic
pramozine
35
counterirritant that provides sensation of cool by stimulating TRPM8 receptors
menthol
36
topical administration formulations have 7 potency classes with many clinicians using one or more from each so that it is possible to taper down to the lowest dose needed to control inflammation after establishing control
glucocorticoids
37
important for optimal wound healing
nutrition
38
characterizes the topical glucocorticoids that should be applied to face
low potency
39
refers to agents such as glycerin
humectants
40
very important component of skin care for health care providers
moisturizers
41
common cause of diarrhea due to antibiotic-associated colitis
C. difficile
42
peptide antibiotic with efficacy against gram-negative bacteria including pseudomonas
polymixin B
43
synthetic insecticide similar to that of chrysanthemums
permethrin
44
biologic DMARD directed against IL-17a
secukinumab
45
titanium dioxide is an example that could be applied
sunshade
46
applied to inanimate objects to kill microbes
disinfectant
47
topical retinoid administered for the treatment of acne
tretinoin
48
topical antihistamine
doxepin
49
example of a body region where topically applied agents would be rapidly absorbed
axilla
50
chronic kidney disease
pruritis
51
local vasoconstriction due to blood volume deficit
oxygenation
52
urea
horny substance softener
53
blocking this radiation was only goal of early sunscreens; also used to treat psoriasis
UVB
54
most important component of infection control
hand hygiene
55
alpha 2 adrenergic agonist used as topical vasoconstrictor to treat rosacea
brimonidine
56
very useful
gloves
57
form on surfaces
biofilms
58
refers to substances in moisturizers that form an oily layer to trap water in the skin/treat dry skin; petrolatum
emollients
59
to heal best
moist
60
both real and fake are well-documented reservoirs for spreading infections in the clinical environment
fingernails
61
delayed hypersensitivity reaction that can be caused by substances such as latex and drugs such as neomycin and bacitracin; sometimes induced as treatment of skin disorder
contact dermatitis
62
topical immune response modifier used to treat actinic keratoses and basal or squamous carcinomas; also used to treat genital warts
imiquimod
63
benzophenones and dibenzoylmethanes are now widely used in these to protect skin
sunscreen
64
antibiotic that works similar to macrolides
clindamycin
65
effective topical therapy for actinic keratoses
5-fluorouracil
66
topical imidazole used to treat nail fungus
efinaconazole
67
effective treatment for acne primarily because of its simple/easy to follow strategy with otherwise standard anti-acne agents
Proactiv
68
platelet-derived growth factor that stimulated diabetic ulcer repair
becaplermin
69
useful topically for fungal infections such as jock itch and athlete’s foot and systemically for fungal nail infections
terbinafine
70
anti-inflammatory agent known since ancient times
salicylic acid
71
local anesthetic found in topical treatments to relieve pain
lidocaine
72
widely used OTC antifungal agent for topical and vaginal infections
clotrimazole
73
mixture of zinc oxide and iron oxide in lotion that cools the skin
calamine
74
most difficult infectious agent to destroy
prions
75
drug class useful for systemic treatment of acne
tetracycline
76
macrolide antibiotic
erythromycin
77
biologic agents that target this are among the agents useful for psoriasis
TNF alpha
78
potent vasodilator due to hyperpolarization via activation of K+ channels
minoxidil
79
orally administered insecticide to treat ectoparasites
ivermectin
80
most common handwashing error in clinical setting
inadequate time
81
~50% water and 50% oil with an emulsifier
creams
82
imidazole antifungal drug applied topically for range of fungal infections
ketoconazole
83
prototypical non-steroid androgen antagonist
flutamide
84
monoclonal antibody against IL-12 and IL-23
ustekinumab
85
retinoid administered orally for treatment of severe acne
isotretinoin
86
among the imidazole drugs commonly used to treat vulvovaginal candidiasis
miconazole
87
orally administered phosphodiesterase type 4 inhibitor used to treat moderate-to-severe plaque psoriasis
apremilast
88
among OTC drugs used to treat jock itch and athlete’s foot; like terbinafine
tolnaftate
89
good wound coverings during the debridement phase of healing
hydrogels
90
peptide antibiotic with activity against gram-positive organisms and some anaerobes; only applied topically to limit systemic toxicity
bacitracin
91
the formation of one of these after drug application to the skin may prolong its half-life enough to permit 1/day dosing
reservoir
92
antifungal agent reluctantly used systemically but also has topical effects limited to candida infections
amphotericinb
93
comprised of ~20% water and 80% oils
ointments
94
inhibitors of this signaling pathway can be used to treat advanced basal cell carcinoma (but usually treated surgically and/or topically)
hedgehog
95
counterirritant that stimulates TRPV1 channels to cause sensation of heat
capsaicin

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