Derm Uworld

Question 1

common spots for warfarin induced necrosis

Answer 1

breast, buttocks,thigh and abdomen

Question 2

managment of warfarin induced necrosis

Answer 2

Vit K and warfarin discontinued if necrosis continues

Question 3

leading cause of sepsis psot burn

Answer 3

infection of staph or pseudomonas

Question 4

child with complicated hemangioma, management?

Answer 4

beta blockers

Question 5

type of hemangioma on infant

Answer 5

superficial

Question 6

type IV HS

Answer 6

delayed

T cell and macrophage mediated

Question 7

Which HS is autoAb mediated

Answer 7

Type II

IgG and IgM

Question 8

which HS is Ab-Ag immune complex

Answer 8

type III

Question 9

2 day old has scattered erythematous macules and papules all over body

Answer 9

erythema toxicum neonatorum

no Tx

Question 10

Tx staph scalded skin syndrome

Answer 10

oxacillin, nafcillin or vanco

Question 11

dermatitis herpetiformis

Answer 11

erythematous papules and vesicles and bullae that are symmetric in herpetiform arrangement on extensor surfaces, upperback and buttocks

Question 12

dermatitis herpetiformis is assoc with

Answer 12

gluten sensitive enteropathy (celiacs)

Question 13

Tx for dermatitis herpetiformis

Answer 13

dapsone

Question 14

eczema herpeticum

Answer 14

primary HSV infection
painful vesicles with punched out erosions and hemorrhagic crusting
fever and lymphadenopathy are common

Question 15

Tx for eczema herpecticum

Answer 15

acyclovir

Question 16

18 year old Tx for acne has extreme reaction to sunburn

Answer 16

doxycycline induced phototoxicity

Question 17

ichthyosis vulgaris

Answer 17

normal skin at birth with progression to dry scaly skin
horney plates over extensor surfaces
sparing of face and diaper area
worsens in winter

Question 18

senile purpura is from what

Answer 18

perivascular CT atrophy

Question 19

farmer with persistent ulcer on lower lip

Answer 19

squamous cell carcinoma is most common

Question 20

what would you find on Bx of SCC

Answer 20

invasive cords of squamous cells with keratin pearls

Question 21

histo shows invasive clusters of spindle cells surrounded by palisaded basal cells

Answer 21

BCC

Question 22

scaly erythematous patch on scalp that progresses to alopecia with residual black dot

Answer 22

tinea capitis

Question 23

pityriasis versicolor

Answer 23

malassezia globosa
hypopigmented lesions
fine scale
pruritis

Question 24

Dx pityriasis versicolor

Answer 24

KOH preparation show hyphae and yeast cells in spaghetti and meatbals pattern

Question 25

Tx of pityriasis versicolor

Answer 25

topical ketoconazole, terbinafine or selenium sulfide

Question 26

which skin cancer has perineural invasion causes numbness and paresthesias

Answer 26

SCC

Question 27

marjolin ulcer

Answer 27

SCC in a burn wound | enlarging nodule with persistent drainage

Question 28

Tx bullous pemphigoid

Answer 28

topical clobetasol

Question 29

what causes bullous pemphigoid

Answer 29

IgG autoAb against hemidesmosome and BM zone

Question 30

skin Bx of bullous pemphigoid

Answer 30

IgG and C3 deposits along BM

Question 31

clobetasol

Answer 31

high potency topical corticosteroid

Question 32

what drug can trigger shingles

Answer 32

tnf alpha inhibitors

Question 33

what type of HS rash is scabies

Answer 33

type IV

Question 34

what drugs likely cause stevens johnson syndrome

Answer 34

sulfonamides, NSAIDs anticonvulsants and allopurinol

Question 35

difference steven johnson syndrome and toxic epidermal necrolysis

Answer 35

SJS 30% body surface

Question 36

snad paper like skin lesion

Answer 36

actinic keratosis

Question 37

dermatofibroma

Answer 37

benign fibroblast proliferation firm hyperpigmented nodules on lower extremities dimpling in center when pinched!

Question 38

skin tags are assoc with

Answer 38

insulin R pregnancy crohns

Question 39

porphyria cutanea tarda is assoc with

Answer 39

hep C

Question 40

sudden onset severe psoriasis assoc with

Answer 40

HIV

Question 41

severe seborrheic dermatitis assoc with

Answer 41

HIV | parkinson

Question 42

pyoderma gangrenosum assoc with

Answer 42

IBD

Question 43

explosive onset multiple itchy seborrheic keratosis

Answer 43

GI malignancy

Question 44

what to use for topical glucocorticoid replacement for face

Answer 44

tacrolimus

Question 45

Tx tinea corporis

Answer 45

clotrimazole or terbinafine topicals

Question 46

monomorphous erythematous papules in someone with SLE | no comedomes

Answer 46

medication side effect steroid induced folliculitis prednisome

Question 47

what autoimmune diseases are assoc with vitiligo

Answer 47

``` pernicious anemia, autoimmune thyroid like graves type I DM primary adrenal insufficiency hypopituitarism alopecia areata ```

Question 48

staph scalded skin syndrome | worse in kids or adults

Answer 48

adults

Question 49

what to do for frsotbite

Answer 49

rapid rewarming with warm water

Question 50

pemphigus vulgaris

Answer 50

easy separation of epidermis on superfiical pressure IgG deposits intercellularly in epidermis AutoAb againse desmoglein

Question 51

Tx pemphigus vulgaris

Answer 51

steroids

Question 52

bullous pemphigoid

Answer 52

no oral lesions benign tense blisters IgG and C3 deposits

Question 53

tx for moderate inflammatory acne

Answer 53

topical retinoids benzoyl peroxide add topical antibiotics

Question 54

Tx porphyria cutanea tarda

Answer 54

phelbotomy hydroxychloroquine INF alpha with Hep C patients

Question 55

HSP

Answer 55

IgA mediated luekocytoclastic vasculitis

Question 56

sings of HSP

Answer 56

``` palpable purpura arthritis abdominal pain intussusceptions renal disease like IgA nephropathy ```

Question 57

Tx HSP

Answer 57

supportive hydration and NSAIDs | cna hospitalize with sytemic glucocorticoids if severe

Question 58

renal Bx in HSP

Answer 58

IgA deposition in mesangium

Question 59

erysipelas

Answer 59

strep limited to epidermis and dermis raised sharp borders with intense erythema

Question 60

Graft versus host is acittvaiton of what

Answer 60

donor T lymphocytes

Question 61

organs effected in graft vs host

Answer 61

skin intestine and liver

Question 62

where does vitiligo preferentially occur

Answer 62

around orifices

Question 63

what causes vitiligo

Answer 63

autoimmune destruction melanocytes