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Flashcards in Derm Uworld Deck (63):
1

common spots for warfarin induced necrosis

breast, buttocks,thigh and abdomen

2

managment of warfarin induced necrosis

Vit K and warfarin discontinued if necrosis continues

3

leading cause of sepsis psot burn

infection of staph or pseudomonas

4

child with complicated hemangioma, management?

beta blockers

5

type of hemangioma on infant

superficial

6

type IV HS

delayed
T cell and macrophage mediated

7

Which HS is autoAb mediated

Type II
IgG and IgM

8

which HS is Ab-Ag immune complex

type III

9

2 day old has scattered erythematous macules and papules all over body

erythema toxicum neonatorum
no Tx

10

Tx staph scalded skin syndrome

oxacillin, nafcillin or vanco

11

dermatitis herpetiformis

erythematous papules and vesicles and bullae that are symmetric in herpetiform arrangement on extensor surfaces, upperback and buttocks

12

dermatitis herpetiformis is assoc with

gluten sensitive enteropathy (celiacs)

13

Tx for dermatitis herpetiformis

dapsone

14

eczema herpeticum

primary HSV infection
painful vesicles with punched out erosions and hemorrhagic crusting
fever and lymphadenopathy are common

15

Tx for eczema herpecticum

acyclovir

16

18 year old Tx for acne has extreme reaction to sunburn

doxycycline induced phototoxicity

17

ichthyosis vulgaris

normal skin at birth with progression to dry scaly skin
horney plates over extensor surfaces
sparing of face and diaper area
worsens in winter

18

senile purpura is from what

perivascular CT atrophy

19

farmer with persistent ulcer on lower lip

squamous cell carcinoma is most common

20

what would you find on Bx of SCC

invasive cords of squamous cells with keratin pearls

21

histo shows invasive clusters of spindle cells surrounded by palisaded basal cells

BCC

22

scaly erythematous patch on scalp that progresses to alopecia with residual black dot

tinea capitis

23

pityriasis versicolor

malassezia globosa
hypopigmented lesions
fine scale
pruritis

24

Dx pityriasis versicolor

KOH preparation show hyphae and yeast cells in spaghetti and meatbals pattern

25

Tx of pityriasis versicolor

topical ketoconazole, terbinafine or selenium sulfide

26

which skin cancer has perineural invasion causes numbness and paresthesias

SCC

27

marjolin ulcer

SCC in a burn wound
enlarging nodule with persistent drainage

28

Tx bullous pemphigoid

topical clobetasol

29

what causes bullous pemphigoid

IgG autoAb against hemidesmosome and BM zone

30

skin Bx of bullous pemphigoid

IgG and C3 deposits along BM

31

clobetasol

high potency topical corticosteroid

32

what drug can trigger shingles

tnf alpha inhibitors

33

what type of HS rash is scabies

type IV

34

what drugs likely cause stevens johnson syndrome

sulfonamides, NSAIDs anticonvulsants and allopurinol

35

difference steven johnson syndrome and toxic epidermal necrolysis

SJS 30% body surface

36

snad paper like skin lesion

actinic keratosis

37

dermatofibroma

benign fibroblast proliferation
firm hyperpigmented nodules on lower extremities
dimpling in center when pinched!

38

skin tags are assoc with

insulin R
pregnancy
crohns

39

porphyria cutanea tarda is assoc with

hep C

40

sudden onset severe psoriasis assoc with

HIV

41

severe seborrheic dermatitis assoc with

HIV
parkinson

42

pyoderma gangrenosum assoc with

IBD

43

explosive onset multiple itchy seborrheic keratosis

GI malignancy

44

what to use for topical glucocorticoid replacement for face

tacrolimus

45

Tx tinea corporis

clotrimazole or terbinafine topicals

46

monomorphous erythematous papules in someone with SLE
no comedomes

medication side effect
steroid induced folliculitis
prednisome

47

what autoimmune diseases are assoc with vitiligo

pernicious anemia, autoimmune thyroid like graves
type I DM
primary adrenal insufficiency
hypopituitarism
alopecia areata

48

staph scalded skin syndrome
worse in kids or adults

adults

49

what to do for frsotbite

rapid rewarming with warm water

50

pemphigus vulgaris

easy separation of epidermis on superfiical pressure
IgG deposits intercellularly in epidermis
AutoAb againse desmoglein

51

Tx pemphigus vulgaris

steroids

52

bullous pemphigoid

no oral lesions
benign
tense blisters
IgG and C3 deposits

53

tx for moderate inflammatory acne

topical retinoids
benzoyl peroxide
add topical antibiotics

54

Tx porphyria cutanea tarda

phelbotomy
hydroxychloroquine
INF alpha with Hep C patients

55

HSP

IgA mediated luekocytoclastic vasculitis

56

sings of HSP

palpable purpura
arthritis
abdominal pain
intussusceptions
renal disease like IgA nephropathy

57

Tx HSP

supportive hydration and NSAIDs
cna hospitalize with sytemic glucocorticoids if severe

58

renal Bx in HSP

IgA deposition in mesangium

59

erysipelas

strep
limited to epidermis and dermis
raised sharp borders with intense erythema

60

Graft versus host is acittvaiton of what

donor T lymphocytes

61

organs effected in graft vs host

skin intestine and liver

62

where does vitiligo preferentially occur

around orifices

63

what causes vitiligo

autoimmune destruction melanocytes