Derma step 1 Flashcards
(20 cards)
Intensely pruritic rash
Worse at night
Close interpersonal contact
Erythematous papules
Rash on flexor surface of wrist,axilla,finger webs,palm
What is disease?
Scabies
Middle aged woman,
lipid laden macrophages on biopsy of upper eyelid
What is its and what condition causes it?
Its xanthalesma and cause is primary biliary cholangitis due to hyperlipidemia
Which oral medication is given for hair loss in men and what happens to testosterone,DHT and estradiol levels after that medication?
Finasteride( 5 alpha-reductase inhibitor) stops the conversion of testosterone to DHT.
Hence testosterone levels rise, DHT levels fall
Testosterone is then converted to estradiol leading to gynecomastia as a side effect.
What do black and brown, red, and lastly grey and white areas on melanoma represent?
1.black and brown shows advancing neoplastic melanocytes
2.red shows vessel ectasia(dilation) and local inflammation.
3.grey and white areas show melanocyte regression
A raised scar,flattens out after a few weeks/months by which process and who does it?
It occurs by process of remodelling and is done by MMP (matrix metallo-proteinases)
Which virus causes vesicular rash and follows dermatomal distribution( affecting one side only) and its feature?
Herpes Zoster Virus(Shingles) characterized by multinucleated cells with intranuclear inclusion
Which cytokine over-expression causes scar to become big even after smaller injuries?
TGF-B
Which cell has shape of tennis racquet?
Langerhan cell which is an APC
Which enzyme does terbinafine inhibit?
Squalene epoxidase
Unilateral vesicular rash involving XYZ dermatome,older patient,with neuropathic pain, what is it?
Herpes Zoster infection (Shingles)
Necrotic ulcers cos of insufficient blood flow, with febrile neutropenia is associated with which disease and causative organism?
Ecthyma Gangrenosum caused by Pseudomonas Auraginosa
Recurrent nose bleeds with spider like lesion on lips oronasopharnyx GI plus respiratory tract urinary tract is whixh disease?
Osler Weber Rendu Syndrome (Hereditary hemorrhagic telengictasia)
Irritant contact diaper dermatitis is caused by what?
Increase in local skin ph by fecal bacteria
Rod-shaped kinetoplasts are seen in which disease and caused by which organism?
Disease is leishmaniasis caused by sand fly bite.
Walking barefoot on moist soil causes which infection that has serpiginous tracks ?
Hookworm infection
Intensely/extremely pruritic rash
Particularly aggravated at night
Rash on feet,hand(web spaces),genitalia,umbilicus,axilla
Spread thru direct person-person contact
What is it?
Scabies
Vancomycin and opiods (eg morphine)
Causes IgE-dependent or IgE-independent mast cell degranulation?
IgE Independent…
Hidradenitis suppurativa occurs in which areas and what is its pathogenesus?
Occurs in axilla medial thigh and groin regions
Caused by occlusion of folliculopilosebaceous units
Skin and nerve infection is seen in which disease
Leprosy
Low grade fever,lesion in oral cavity and distal extremities seen in which disease and caused by which organism?
Hand foot and mouth disease.
Caused coxsackie(enteroviral) infection.
