Dermatitis/Eczema Flashcards

(37 cards)

1
Q

What are some features of acute phase eczema?

A

Papulovesicular, red erythematous rash, oedema, ooze, scaling, crusting

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2
Q

What are some features of chronic eczema?

A

Lichenification (thickening), elevated plaques, increased scaling

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3
Q

What are the 4 main features of an eczema rash?

A

Itchy, ill-defined, erythematous, scaly

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4
Q

What is the main histological feature of eczema?

A

Spongiosis

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5
Q

What is the pathogenesis of contact allergic dermatitis?

A

Delayed type IV reaction

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6
Q

What is the pathogenesis of contact irritant dermatitis?

A

Trauma

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7
Q

What is the pathogenesis of atopic eczema?

A

Genetic and environmental factors resulting in inflammation

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8
Q

Drug related dermatitis can be what types of reaction?

A

Type I or IV

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9
Q

What is the pathogenesis of photosensitive eczema?

A

Reaction to UV light

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10
Q

What is the pathogenesis of lichen simplex eczema?

A

Physical trauma to the skin through scratching

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11
Q

What is the pathogenesis of stasis eczema?

A

Physical trauma to the skin through hydrostatic pressure

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12
Q

Will contact allergic dermatitis have an effect the first time an individual is exposed to the antigen?

A

No, it will occur on subsequent antigen exposure

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13
Q

How are substances causing contact allergic dermatitis identified?

A

Patch testing

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14
Q

Describe contact irritant dermatitis?

A

Non-specific physical irritation rather than a specific allergic reaction

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15
Q

What is nappy rash?

A

A contact irritant dermatitis to urine

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16
Q

Which type of eczema is most likely to have occupational implications?

A

Contact irritant

17
Q

Itch is a major feature of atopic eczema. What are some consequences that this can have?

A

Can cause sleep disturbance which can cause neurocognitive impairment

18
Q

Along with itch, what are some other features of atopic eczema?

A

Ill-defined erythema, scaling and generalised dry skin

19
Q

What is the distribution of atopic eczema?

20
Q

What other diseases is atopic eczema also associated with?

A

Other atopic diseases such as allergic rhinitis (hay fever), asthma and food allergies

21
Q

What are some chronic changes of atopic eczema?

A

Lichenification, excoriation, secondary infection

22
Q

Crusting of atopic eczema can often indicate what?

A

Staph aureus infection

23
Q

Where will atopic eczema be seen in infants?

A

Cheeks and extensor surfaces

24
Q

What is eczema herpeticum? What does it look like?

A

An infection in atopic eczema caused by HSV. Monomorphic punched out lesions.

25
What is the UK diagnostic criteria for eczema?
Itch, plus 3 or more of the following: visible flexural rash, history of a flexural rash, personal history of atopy (or family history if < 4), general dry skin, onset < 2 years
26
What is the first line therapy for atopic eczema?
Emollients and avoidance of triggers
27
What is the 2nd line therapy for atopic eczema?
Topical steroid
28
What are some more severe treatment options for atopic eczema?
Phototherapy (UVB), immunosuppressants
29
What is the main gene implicated in atopic eczema?
Filaggrin
30
What is discoid eczema?
Patches of eczema which form in circles
31
What is a common clinical sign of photosensitive eczema?
Cut off at the collar
32
How may stasis eczema appear?
With prominent veins
33
What is pompholyx eczema?
Spongiotic vesicles on the hands
34
What is seborrhoea dermatitis?
A light rash on a baby's head
35
If topical steroids are not used as 2nd line therapy for atopic eczema, what is another option?
Calineurin inhibitor
36
What management should occur if there is eczema herpeticum?
Hospitalisation (IV acyclovir)
37
If there is infection of eczema, what would be the first line antibiotic? How would this be given?
Flucloxacillin (topical if localised, oral if extensive)