Dermatologic Manifestations of Allergy

Question 1

Atopic Dermatitis:

Answer 1

• Disease of childhood
• Extensors, face, neck in children
• Flexors in any age group
• Spars groin and axillary region
• Early age of onset
• Atopy: personal or family history
• Serum IgE elevated
• Eosinophilia
• Type I Hypersensitivity

Question 2

Contact Dermatitis:

Answer 2

• Type IV Hypersensitivity
• Lichenified erythematous plaques with chronic
• Can be an allergy or irritant -> irritant more common cause
• Most common occupational skin disease in the US
• Distribution is single most important clue to diagnosis

Question 3

Urticaria:

Answer 3

• Wheal-and-flare reaction
• Blanch with pressure as dilated vessels are compressed
• Superficial Dermis

Question 4

Angioedema:

Answer 4

• Deep Dermis and Subcutaneous Tissue

- Lips and tongue affected

Question 5

Food Allergy:

Answer 5

• IgE mediated

- Isolated to GI tract or Skin

Question 6

Drug Allergy:

Answer 6

• 12% of children treated with an antibiotic will experience a cutaneous reaction
• Steven Johnson Syndrome
• Drug Eruption