Dermatology Flashcards by Roshni Kestur

Guttate psoriasis

H/o preceding streptococcal infection
Droplet shaped
Self limiting
Recovery hastened by:
Phototherapy/topical steroids/emollients

How well did you know this?

Not at all

Perfectly

Phototoxic skin reactions

Confluent erythema
Seen with Ciprofloxacin (all Quinolones)

How well did you know this?

Not at all

Perfectly

Ustekinumab

Used in psoriasis
Anti IL 12 and IL 23 monoclonal antibody

How well did you know this?

Not at all

Perfectly

HPV infection on fingers

Kissing warts, adjacent fingers involved

How well did you know this?

Not at all

Perfectly

Traumatic nail change vs subungal melanoma

Hutchinson sign in melanoma: hyperpigmentation (blue/black) of nail bed

How well did you know this?

Not at all

Perfectly

Onychomycosis

Yellow/brown
Brittle crumbling nails

How well did you know this?

Not at all

Perfectly

Side effects of isotretinoin

Anaemia
Thrombocytopenia/thrombocytosis
Rise in ESR

How well did you know this?

Not at all

Perfectly

Keloid scars treatment

intralesional triamcinalone

How well did you know this?

Not at all

Perfectly

Co-prescription of tetracyclines and isotretinoin must be avoided

Increased risk of benign intra-cranial HTN
and pregnancy test is a must before istretinoin

How well did you know this?

Not at all

Perfectly

Chediak-Higashi syndrome

Recurrent bacterial infections
Thrombocytopenia
Neurological symptoms
Inclusion bodies and lysosomal granules in leucocytes
Albinism

How well did you know this?

Not at all

Perfectly

Oculo-cutaneous albinism

type 1: complete absence of melanin
type 3: reddish hair, blue/grey eyes

How well did you know this?

Not at all

Perfectly

Thyroid acropachy

Seen in Graves
Soft tissue swelling and clubbing in hands

How well did you know this?

Not at all

Perfectly

De quervain’s thyroiditis

Sub acute hyperthyroidism biochemically
Malaise and neck pain
Post viral illness

Treated with NSAIDs and Pred/propranolol
Not Carbimazole

Decreased uptake on radio-nucleotide scan

How well did you know this?

Not at all

Perfectly

Drug of choice in late pregnancy for hyperthyroid?

Carbimazole
Risk of maternal hepatotoxicity with PTU

How well did you know this?

Not at all

Perfectly

Drug of choice in breast feeding for hyperthyroid?

PTU

How well did you know this?

Not at all

Perfectly

Drug of choice in early pregnancy (first trimester) for thyrotoxicosis?

PTU

How well did you know this?

Not at all

Perfectly

Mc Cune Albright syndrome

Precocious puberty
Hyperthyroidism
Cafe au lait spots U/L
H/o fractures due to polyostotic fibrous dysplasia
Increased risk of osteosarcoma and breast cancer

How well did you know this?

Not at all

Perfectly

Thyrotoxicosis factica

Low thyroglobulin levels
Abuse of thyroxine tablets
No goitre

How well did you know this?

Not at all

Perfectly

Post partum thyroiditis?

Anti TPO positive
Upto 6 months post partum

How well did you know this?

Not at all

Perfectly

Tinea capitis treatment?

Griseofulvin for 4-6 weeks (Microsporum)
Terbinafine (Trichophyton)
Itraconazole
Fluconazole

Topical ketoconazole not as effective

How well did you know this?

Not at all

Perfectly

Tinea incognito

When appearance of tinea has been altered by the use of steroid creams

How well did you know this?

Not at all

Perfectly

Cryptococcal meningitis

Initial cough, lung symptoms (pneumonitis)
Neurotropic encapsulated yeasts: Meningitis
Skin lesions like molluscum contagiousum
Rx: Amphotericin B, Flucytosine

How well did you know this?

Not at all

Perfectly

Striae in pregnancy due to which hormone?

Cortisol

How well did you know this?

Not at all

Perfectly

Erythema multiforme seen in?

Mycoplasma
HSV (M/C)
Penicillins
Sulphonamides

(target shaped lesions with burning sensation but non-pruritic)

Type 4 hypersensitivity reaction

How well did you know this?

Not at all

Perfectly

EM major?

Seven Johnson's syndrome Mucosal involvement+

Pemphigoid gestationis?

Bullous pemphigoid of pregnancy Rx: Topical steroids

Bullous pemphigoid association?

Psoriasis Dementia CVA Parkinson's Rx: Oral steroids

Which cell infiltration in pyoderma gangrenosum?

Neutrophils

Treatment escalation in pyoderma gangrenosum

Topical steroids/topical Tacrolimus* Oral steroids Infliximab/Adalimumab (TNF alpha inhibitors) Topical/oral calcineurin inhibitors (Tacrolimus)

Lupus vulgaris

Cutaneous TB Developing countries

Granuloma annulare

Skin biopsy and histology: Necrobiotic collagen surrounded by palisading histiocytes + lymphocytic infiltrate a/w HIV, lymphoma

High risk HPV subtypes

16 18 31 45

Minocycline side effect

Hyperpigmentation

Drug induced pseudo lymphoma syndrome

anti epileptics antibiotics anti arrhythmics anti histamines anti depressants

Lofgren syndrome

Fever B/L lymphadenopathy Erythema nodosum: neutrophilic panniculitis (a/w HLA B27) Rx: NSAIDs, steroids, immunosuppressants compression socks (Acute sarcoidosis)

Erythema induratum

Posterior calves Indurated nodules and plaques TB

Erythema marginatum

Acute rheumatic fever Group A beta haemolytic streptococci

Caplan's syndrome

RA Pneumoconiosis

Hereditary hemorrhagic telengectasia

Osler-Weber-Rendu Autosomal dominant Telengectasia of skin and buccal mucosa Epistaxis GI bleed due to AVM AVM in GI, lung, liver, brain Microcytic anaemia

Prophylactic Aciclovir

400mg BD for 1 year >6 episodes of HSV in 1 year

Standard treatment for genital herpes

Aciclovir 200mg five times/day OR 400mg TDS

Herpetic whitlow

Digital herpes simplex

Treatment of hair loss due to androgen excess

Topical Minoxidil Finasteride (anti-androgen)

Pseudoxanthoma elasticum

Angioid streaks in retina Gi haemorrhage Skin changes in axilla and neck

Porphyria cutanea tarda

Fragility and skin blistering on sun exposed areas Milia at site of healing blisters Deficiency of uroporphyrinogen decarboxylase RF: alcohol, sunshine, estrogen

Morphea ie: localised scleroderma

Indurated/thickened plaques in females eg: after piercing/trauma/infection hypo/hyperpigmented plaque Rx: steroids/phototherapy/methotrexate

Dermatitis herpetiformis Rx:

Gluten free diet Dapsone Resistant cases: Oral sulphapyridine NOT steroids

Psoriasis treatment escalation

Topical steroids/Calipotriol ie. Vit D Narrow band UVB (if no past h/o skin cancer) Methotrexate, ciclosporin, phototherapy Adalimumab/Infliximab/Etanarcept (after excluding TB; TNF alpha antagonist) Ustekinumab (Anti IL 12/23) Acitretin in severe pustular etc psoriasis not arthritis ?dimethyl fumarate

How long to avoid pregnancy if taking Acitretin?

3 years after 4 weeks before

Pustular psoriasis

Urgent hospital admission Sin biopsy: sun corneal pustules and neutrophilic infiltration Rx: topical emollients/topical steroids

DH histology features?

IgA deposits in dermo-epidermal junction

Psoriasis drug triggers?

Lithium Anti-malarials NSAIDs Beta blockers Lisinopril

Gutatte psoriasis Rx:

Narrow band UVB

Lupus pernio

Nose turning red over months Cutaneous Sarcoid

Lichen planopilaris

receding hair line (peri folliculitis) plus lichen sclerosis

What is lichen planus associated with?

Koebner's phenomenon Liver diseases

LP like reaction caused by which drugs?

Thiazides Beta blockers Phenothiazines Anti malarials Methyl dopa

Koebner's phenomenon is seen in?

Psoriasis Lichen planus Vitiligo

Capillaritis

Due to prolonged exercise Progressive pigmented purport Schamberg disease Pin-point macules and Cayenne pepper spots

HSP histology

Perivascular IgA deposits

Erythema nodosum Rx:

Colchicine

Erythema gyratum repens

Paraneoplastic Erythematous woody grainy appearance

Drug used prior to pituitary surgery in Cushing's with multiple medical co-morbidities

Ketoconazole

What is yellow nail syndrome associated with?

Bronchiectasis Rx: Spontaneous or Vitamin E

Pityriasis rosea

First herald patch Then crops of salmon pink lesions along cutaneous lines Christmas tree distribution HHV 6,7

Bazar syndrome

Acrokeratitis paraneoplastica Squamous cell ca of upper digestive tract

Drugs causing photosensitive rash

P Phenothiazines Q Quinine R Retinoids S Sulphonamides T Tetracyclines

Treatment of hidradenitis suppurativa?

Oral Tetracyclines (Doxy or Lyme)

Dermatology Flashcards

(69 cards)