Dermatology Flashcards
(60 cards)
What is acne vulgaris?
Disease of the pilosebaceous unit often due to excessive androgenic response leading to excess sebum production building up and blocking these follicles with keratin plugs
How does acne vulgaris present/appear? (Describe)
Often face, neck and upper trunk
Open or closed Comedones, pustules or Papule
Scarring
What bacterium can colonise the pilosebaceous ducts with acne vulgaris?
Cutibacterium acnes
What condition may you consider if a patients has irregular periods, hirsutism and acne vulgaris?
PCOS
What is the management for mainly Comedonal acne?
topical retinoids like Adapalene or Adapalene + Benzoyl peroxide
What is the management for mild to moderate acne (papule/pustular)?
When should the patient be reviewed?
Topical retinoid (ADAPALENE) + Benzoyl peroxide
Review in 12 weeks and try another treatment option
What is the management for a mild to moderate acnecne vulgaris if the patientst hasn’t repsonded to the first 2 rounds of treatment following 2 review periods?
Treat with the management for moderate to severee acne
What is the management for moderate to severe acne vulgaris?
Topical retinoid (ADAPALENE) + Benzoyl peroxide + ORAL ANTIBIOTIC (Lymecycline or doxycycline)
Topical Adapalene + Topical Benxoyl peroxide + Oral lymecycline
When are patients reviewed following treatment for moderate to severe acne?
What happens if theres been no improvement at this stage?
12 weeks
No improvement = refer to dermatology and try another treatment option while waiting
What management shouldd take place if a patients moderate to severe acne r has completely cleared after 12 weeks?
What if it’s partially improved?
cleared = STOP oral abx, continue adapalene + Benzoyl peroxide
partial improvement = continue treatment for another 12 wks (topical Adapalene + Benzoyl peroxide + oral lymecycline)
When i s acne consider moderate to severe?
> 35 inflammatory lesions
3 or more nodules
ANY TIME THE CHEST OR BACK IS AFFECTED
What is atopic Eczema/dermatitis?
Dermatitis is that usually has a genetic factor and environmental factor to it
What are the atopic conditionsns?
Hayfever (allergic rhinitis)
Asthma
Eczema
what are some triggers to eczema?
Soap/detergents
Rough clothing
overheating
Stress
skin infections toons
Animal dander
foods
House dust mites
What parts of the body doess eczema commonly affect?
flexural surfaces
Face in infants
What is the morphology of eczema?
Ill defined areas of erythemama
dry skin (flexures)
Vesicles, weepy and crusty patches in flare ups
Excoriations
Lichenification
What is the management for eczema without signs of infection?
Regular emolient + corticosteroid (hydrocortisone cream, Betamethasone/betnovate or clobetasone/eumovate)
How long should the topical corticosteroids given for eczema but applied daily for?
2 weeks typically
What alternate medications can be given instead of corticosteroids if the area of eczema is of thin skin like the face or near the eyes?
Calcineurin inhibitors
What is an example of a topical calcineurin inhibitor for eczema?
Protopic (tacrolimus and ointment)
What are some commonly prescribed emollients?
E45 cream
Zerobase cream
Hydromol
Zeroderm
What is the pathophysiology of psoriasis?
Overactive keratinocyte proliferation
How does psoriasis present?
Red scaly patches on the skin often on the extensor surfaces