Dermatology Flashcards
(48 cards)
What is skin responsible for?
temperature regulation, insulation and sensation (touch)
Skin acts as what kind of barrier?
physical and immunologic
What are the skin components?
Epidermis, dermis, subcutaneous fat, sweat glands, oil glands, hair and nails
What is the deepest layer of the epidermis?
Basal Cell
How long does it take for cells to migrate from basal cell layer to the surface?
4 weeks and then they are shed
What is the second deepest layer of the epidermis?
Stratum Spinosum
What does Stratum Spinosum contain?
keratin
What is keratin?
a fibrous protein that is the major component of stratum spinosum,
what is the second layer of the epidermis?
Stratum Granulosum: cells acquire more keratin and becomes flatter. polysacchharides, gylcoproteins, and lipids are found in this later that holds together the cells of the Stratum Corneum
What is the top layer of the epidermis?
Stratum Corneum; cells are large, flat, and filled with keratin. 15-25 layers on most surface. 100 layers on palms and soles
What are melanocytes and where are they produced?
pigment producing cells found in the basal cell layer that provide protect from UV radiation
What are Langerhan cells?
derived from bone marrow and are identical to tissue macrophages and present antigens to lymphocytes
Who are soldiers of the skin?
Langerhan cells
What is the layer of skin under Epidermis?
Dermis
What does the dermis contain?
nerves, blood vessels and appendages. Also contains collagen and elastic fibers.
What are eccrine sweat glands and their function?
excrete sweat onto the skin surface in regulation of body temperature. Duct creates pathway to the surface**
Apocrine Sweat glanes
no useful purpose, create odor that is caused by bacteria. Deep in the dermis and reach the skin via the hair follicle.
Hair Follicle
all over the body except palms and soles. Two type: vellus (short, fine) and terminal (thick and coarse)
Anagen Phase
growth phase of hair
Catagen Phase
transitional phase in growth of hair
Telogen Phase
resting phase in the growth of hair
Sebaceous Glands
oil glands that secrete sebum. Found where hair follicles are present.
Nails
made of keratin which is formed from a matrix of dividing epidermal cells. Nails grow at a rate of 0.1 mm a day and toenails even grow slower
Subcutaneous Fat and function
lies between the dermis and the fascia. Insulation, cushion and energy reserve