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Flashcards in Dermatology Deck (161):
1

quid of herpes zoster

rash along dermatomal distribution

2

other name of herpes zoster

shingles

3

rx of shingles(3)

acyclovir
or
valacyclovir
or
famcyclovir

4

patient with sore throat ,after receiving amox develops rash dx?

hypersensitivity type 1

5

rx of hypersentivity syndrome in a patient taking amox

antihistaminic

6

when anti histaminic is good in allergy

when you have no systemic symptom

7

drugs most commonly implicated in hypersensitivity type 1 reaction(5)

B lactam
neuro mxar blocking agents
quinolones
chemo drugs containing platinum
foreign protein chimeric antibodies

8

disease associated with acnthosis nigricans(2)

condition associated with insulin resistance
GI malignancy

9

condition associated with insulin resistance(2)

Diabete type 2
OMPK

10

disease or state associated with multiple skin tags(3)

insulin resistance
pregnancy
chron disease(peri anal fissure)

11

skin condition associated with Hep C

porphyrie cutanea tarda
cutaneous leucocytoclastic vasculitis secondary to mixed cryoglobulinemia

12

condition associated with cutaneous leucocytoclastic vasculitis

palpable purpura

13

disease associated with dermatitis herpetiforme

celiac disease

14

skin manif associated with HIV(2)

severe seborrheic dermatitis
sudden onset of severe psoriasis

15

disease associated with explosive itchy seborrheic keratosis

GI malignancy

16

disease associated with pyoderma gangrenosum

IBD

17

quid of skin tag

pedonculated outgrowth of normal skin

18

flushing of the skin caused by hot drinks,heat and emotion

rosacea

19

rx of rosacea

topical metronidazole

20

quid of rosacea

telangiectasia over cheeks chin and nose

21

actinic keratosis(3)

sunexposed areas
sandpaper like texture
squamous cell carcinoma

22

second most common cause of ca in the US

SCC

23

risk factor for SCC

sunlight exposure

24

biopsy of SCC of skin

polygonal cell withb atypical nuclei at all levels of the epidermis with zone of keratinization

25

the more agressive ca of the skin

SCC

26

rx of cellulitis with systemic symptom(2)

IV nafcilin
or
cefazolin

27

cellulitis with systemic Symptom and MRSA rx?

IV vancomycin

28

physio patho of bullous pemphigoid

IGG and C3 deposits at the dermal epidermal junction

29

medication which can trigger bullous pemphigoid(4)

furosemide
NSAIDS
captopril
penicillamine

30

localisation of bullae in BP

subepidermal

31

workup for bullous pemphigoid

direct immunofluorescence

32

necrotizing fascitis

pain and fever in the zone of a trauma

33

clue for NF

purplish discoloration of the skin with gangrenous changes

34

best rx of NF(2)

debridement
antibio

35

bugs causing necrotizing facitis(3)

staph aureus
group A strepcocci
anaerobes

36

what test to perform in necrotizing fasciitis

check for diabetes

37

antibio used in Necrotizing fasciitis(2)

ampi sulbactam
plus
clyndamycin

38

cause of idiopathic necotizing fasciitis(2)

srotal
or
Penile NF

39

Rx of scabies

5% permethrin cream

40

patient of chronic lip ulceration(3)

malignant
chronic infection
autoimmune

41

cause of malignant lip ulceration

SCC

42

biopsy for SCC

invasion cords of squamous celle with keratin pearls

43

sun exposure occupation plus isolated vermillon ulcer(zone of lower lip)

SCC

44

biopsy for BCC

spindle cells surrounded by palissade basal cells

45

type of acne(3)

comedones
inflammatory acne
nodular cystic acne

46

rx of comedal acne

topical retinoids

47

quid of inflammatory acne

inflamed papules and pustules

48

RX of inflammatory acne (mild)(2)

topical retinoid
plus
benzoyl peroxid

49

moderate inflammatory acne rx(3)

topical retinoid
plus
benzoyl peroxid
plus topical antibio

50

topical antibio used in moderate inflammatory acne(2)

clyndamycin
erythromycin

51

severe inflammatory acne rx(3)

topical retinoid
plus
benzoyl peroxid
topical antibio
plus oral antibiotherapy

52

quid of nodular cystic acne

large nodule > 5mm ,can appear cystic

53

rx of moderate nodular cystic acne(3)

topical retinoids
topical antibio
benzoyl peroxyde

54

rx of severe nodular cystic acne(4)

topical retinoids
topical antibio
benzoyl peroxyde
plus oral antibiotherapy

55

rx of nodular cystic acne rebelle au rx for severe cystic acne next step

add oral isotretinoin

56

quid of herpetic withlow

viral infection of the hand

57

profession at risk for herpetic withlow(2)

dentist
health worker with direct contact with orotracheal lesion

58

Dx of herpetic withlow

cytodiagnostic de TZANCK

59

cause of herpetic withlow

herpes virus type 1 et 2

60

skin lesion in PBC(2)

xanthoma
xanthelasma

61

quid of xanthelasma

benign lesion of medial eyelid characterised by lipid filled macrophages in the dermis

62

why can you have osteoporosis in PBC

inability to absorb fat soluble vit specially vit D

63

cause of angioedema

C1 inhibitor deficiency

64

Symptom of angioedema(3)

face swelling
laryngeal edema
edema of bowel

65

cause number 1 of acquired angioedema

ACE inhibitor

66

physiopatho of edema in hereditary angioedema(3)

no C1 inhibitor
lots of C2b and bradikiine are produced--->
edema

67

causes triggering hereditary angioedema(3)

dental procedure
infection
trauma

68

disease causing C1Q depressed

lupus

69

patient taking drugs for acne develops redness and swelling of the skin when exposure to sun dx?

drug induced phototocixity

70

drug causing phototocic drug eruptions

all cyclines

71

cherry hemangioma appearrance

ti point rouje anba po w

72

strawberry hemangioma

bigger than cherry hemangioma

73

patient presenting difficulty respiratoire and facial edema 2 weeks after beginning ACE inhibitor

ACE inhibitor angioedema

74

why in the same vignette patient has rash problem you dont pick aspirin as the right answer

rash in aspirin appears immediately after taking the drug

75

how ace inhibitor causes angioedema

by inhibiting ACE you have high level of bradikinin

76

when angioedema with ace inhibitor can occur

at any time

77

clue for tinea versicolor

hypopigmented macules that don't tan and don't appear scaly but scale on scraping

78

bug causing tinea versicolor

malasezia furfur

79

Dx of tinea versicolor(2)

KOH preparation
spaghetti or meat balls appearrance

80

rx of Tinea versicolor

selenium sulfide lotion

81

patient with redness and blisters on breast and thighs ,patient taking warfarin

warfarin induced necrosis

82

condition associated with warfarin induced necrosis

protein C deficiency

83

lieu of warfarin induced necrosis(4)

breast
thigh
buttocks
abdomen

84

rx of frostbite

rapid rewarm with warm water (40-44 C)

85

rx of dermatite herpetiforme(2)

dapsone
gluten free diet

86

causativ agent of molluscum contagiosum

poxvirus

87

risk factor for molluscum contagiosum

AIDS with CD4 less than 100

88

rx of molluscum C(2)

curretage
or
application of liquid nitrogen

89

lesion in Molluscum C

papules with central umbilification

90

patient with mole becoming larger what skin examination clue would be more consistent with malignancy

zones of different skin colors

91

features of melanoma(5)

Asymetric lesions
Border irregularities
Color variegation
Diameter > 6 mm
Enlargement or evolution of skin lesion

92

quid of tinea corporis

circular lesion with scaly borders and central clearing

93

bug in tinea corporis

trichophyton rubrum

94

rx of tinea corporis(2)

topical terbinafine 2%
plus
oral griseofulvine

95

clue for seborrheic keratosis(4)

warty appearance
waxy
well circumscribed
stuck on appearance

96

localisaion of herpes simplex(2)

mouth
genital area

97

bug causing chicken pox

varicella zoster (varicelle)

98

quid of shingles

reactivation of varicella zoster

99

pruritic circumferantial rash over wrist

allergic contact dermatidis

100

most commonly involved substance in contact dermatidis(2)

poison ivy
nickel jewelry

101

type of hypersensitivity in allergic contact dermatidis

type 4

102

cells inplicated type 4 hypersensitivity

lymphocyte T

103

rx allergic contact dermatidis(3)

calamine
antihistamines
topical steroids

104

use of oral steroid in contact dermatidis

in sever case

105

quid of stevens jhonson syndrome

erythema multiform major

106

clue for stevens jhonson syndrome(2)

Mucocutaneous lesion
plus
target shaped lesions

107

quid mucocutaneous lesion in steven jhonson syndrome(3)

conjonctivitis
pa ka pipi
paka vale

108

quid of erythema multiform minor(4)

rash occuring after herpes infection
target lesions are present
mucosal invlovement
no systemic symptom

109

patient after working in woods develops vesicules on forearms vesicule full with coagulase negative organism dx

contact dermatidis

110

substance found in wood causing contact dermatidis(2)

sumac
woody shrug

111

why you foun coagulase negative bacteria in vesicle fluid in contact dermatidis

secondary infection by S epidermidis

112

definition of ichtyosis(2)

dry skin and scaly worst during winter season
dry skin with horny plates on the extensor surfaces of limbs

113

clue for senile purpura

ecchymosis in older patient with nothing else

114

cause of senile purpura(2)

perivascular connective tissue atrophy
loss of elastic fiber

115

other name of senile purpura

solar or actinic purpura

116

rx of senile purpura

no rx needed

117

clinic of senile purpura(2)

brown discoloration
dark purple of skin

118

disease associated with vitiligo(6)

pernicious anemia
thyroid disease
diabete type 1
primary adrenal insufficiency
hypopituitarism
alopecie areata

119

thyroid disease associated with vitiligo(2)

graves
autoimmune thyroiditis

120

quid of chalazion

obstruction of mebomian gland

121

CAT in case of reccurent chalazion

meibomian gland carcinoma
also called sebaceous carcinoma

122

best test in case of reccurent chalazion

histopatho

123

Dx differential of chalazion

BCC of the eyelid

124

the most common tumor of the eyelid

BCC

125

most common tumor in mankind

BCC

126

pathology of vitiligo

autoimmune destruction of melanocytes

127

if you see changing mole what to think

eliminer melanoma

128

most commonly drug involved in SJ syndrome(3)

sulfonamide
NSAIDS
Phenytoin

129

drug causing toxic epidermal necrolysis(2) TEN

same as SJ syndrome
barbiturate

130

Between TEN and SJS difference

up to 10 % of the body involved=SJS
more than 30%=TEN

131

nickolsky sign

patches of skin slide off with slightest pressure

132

after marrow transplantation patient develops diarrhea and pruritic maculopapular rash Dx

graft versus host disease

133

physiopatho of graft versus host disease

recognition of host major and minor HLA antigens by donor T cells and activation of T cells and cell mediated immune response

134

target of graft versus host disease(3)

foie
intestin
peau

135

waxy loose scaleswith erythema of scalp ,central face umbilicus interscapular area body fold presternal region
dandruft in hair

dermatidis seborrheic

136

disease associated with seborrheic dermatidis(2)

HIV
Parkinsonism

137

immunologic condition associated with M contagiosum

cellular immuno deficiency
chemo
corticosteroid use

138

patient with slightly elevated lesion ,brown colored measuring > 7mm,with irregular border Dx

Melanoma

139

study of Melanoma

excisionnal biopsy with narrow margin

140

study for melanoma with less than 1 mm depth

excision on 1 cm tumor free margin

141

study for melanoma with more than 1 mm depth

look for a lymph node sentinel study

142

vulgaris pemphigus(2)

flaccid bullae
slightly rubbing of the involved skin causes easy separation of the epidermis=nickolsky sign

143

immunofluorecence finding in pemphigus vulgaris

IGG deposits intercellular in the epidermidis

144

target of antibody in Pemphigus vulgaris

desmoglein

145

Rx of Pemphigus vulgaris

steroids
or azathioprine plus prednisone plus metotrexate

146

flaccid blister

P vulgaris

147

tense blister

P Bullous

148

bug causing acne

propionibacterium acne

149

clue for porphyria cutanea tarda(2)

painless blister of hand
hyperpigmentation hypertrichosis

150

rcause of PCT

deficiency in uroporphyrinogen decarboxylase

151

role of uroporphyrinogen decarboxylase

heme synthesis

152

trigger of PCT

alcohol
estrogen

153

rx of PCT(3)

hydroxychloroquine
or
phlebotomy
interferon @ to rx Hep C

154

Clue fro Necrotizing fasciitis

patient after trauma in leg develops pain and fever

155

rx of scabies

5% permertrin cream

156

general measure for scabies

bedding and clothing should be cleaned or set aside for 2 weeks

157

quif edema producing factor in angioedema(2)

c2B
bradikynin

158

rx of tinea versicolor

selnuim sulfide
ketoconazole shampoo

159

physiopatho of SJS

immune complex mediated

160

quid of stye or Hordeolum(orgelet)

acute infection of eyelids glands

161

zone bastion du psoriasis(5)

scalp
oreille
coude
genou
organes genitaux