Dermatology - Skin and systemic diseases Flashcards Preview

Year 4 - SPM > Dermatology - Skin and systemic diseases > Flashcards

Flashcards in Dermatology - Skin and systemic diseases Deck (15):
1

What is erythema nodosum and what conditions are associated with it?

These are painful blue/red lesions on the anterior shins.
They are associated with the "3's":
- sarcoid
- strep infections
- sulfonamides

They may also occur in TB, OCP, IBD and Behcets

2

What is erythema multiforme?

This is a symmetrical target lesion on the palms, soles and limbs.
Possibly mediated by IgM deposition.
Usually secondary to infection: HSV (70%), mycoplasma

3

What drugs are associated with erythema multiforme?

"SNAPP"
Sulfonamides
Nevirapine, NSAIDS
Allopurinol
Penicillin
carmabazePine

4

What causes Stevens-Johnson syndrome and TEN?

These are severe variants of EM.
Nearly always drug induced.
PC: fever, mucosal and skin ulceration and necrosis.

5

What is pyoderma gengrenosum?

Wide deep ulceration with violaceous border
Purulent surface
Undermined edge
Commonly occurs on the legs
Heals with cribriform (pitted) scars

Associated with IBD, AIH, Wegener's, RA, Leukaemia
Treatment is with high dose systemic steroids

6

What is Livedo reticularis?

These are persistent, mottled blue/red lesions that don't blanch
Commonly found on the legs
Triggered by cold
Causes:
- idiopathic
- vasculitis: RA, SLE, PAN
- obstruction: anti-phos, cryoglobulinaemia
- Sneddon's syndrome: LR + CVAs

7

What rash is associated with rheumatic fever?

Erythema marginatum (circular shaped erythematous rash that resembles the mitral annulus)

8

What is the skin manifestation of Lyme disease?

Erythema chronicum migrans

9

What are the skin manifestations of Crohn's disease?

Perianal ulcers and fistulae
EN
Pyoderma gangrenosum

10

What rash is associated with dermatomyositis? What other features can be present?

Heliotrope rash on eyelids
Shawl sign (macular rash)
Gottron's papules
Mechanic hands
Nailfold erythema, telangiectasia

11

What are the skin manifestations of diabetes mellitus?

Ulcers
Candida
Kyrle disease
Acanthosis nigricans
Necrobiosis lipoidica (shins)
Granuloma annulare (hands, feet)

12

What rash is associated with coeliac disease?

Dermatitis herpetiformis (elbows)

13

Graves disease is associated with this characteristic rash...

Pre-tibial myxoedema

14

What are the skin manifestations of rheumatoid arthritis?

Rheumatoid nodules
Vasculitis (palpable purpura)

15

What are the features of CREST syndrome?

Calcinosis
Reynauds phenomenon
oEsophageal dysmotility
Sclerodactyly
Telangiectasia

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