Dermatomyositis Flashcards
1
Q
Dermatomyositis is an inflammatory condition that causes what?
A
Symmetrical and proximal muscle weakness and characteristic skin lesions
2
Q
It may be idiopathic or may be associated with CT disorders or a malignancy - name 1 of these malignancies
A
- Ovarian
- Lung
- Breast
3
Q
Polymyositis is a variant of dermatomyositis - how is it different?
A
Skin features are less prominent
4
Q
Name 2 skin features
A
- Gottron’s papules (roughened red papules over extensor surfaces of fingers
- Macular rash over back and shoulder
- Photosensitivity
- Dry and scaly hands
- Nail fold capillary dilation
- Heliotrope rash (reddish purple rash) over periorbital region
5
Q
Name 2 other features (apart from skin features)
A
- Raynaud’s phenomenon
- Proximal muscle weakness and tenderness
- Respiratory muscle weakness
- ILD
- Dysphagia and dysphonia
6
Q
What antibody is positive in 80% of patients?
A
ANA
7
Q
Name another antibody that may be positive
A
Antibodies to aminoacyl tRNA synthetases i.e.
- Anti Jo1
- Anti SRP
- Anti Mi 2
